Cholangiocarcinoma history and symptoms: Difference between revisions

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{{Cholangiocarcinoma}}
{{Cholangiocarcinoma}}
{{CMG}};{{AE}} {{PSK}}
{{CMG}};{{AE}} {{F.K}} {{PSK}}
==Overview==
==Overview==
The common symptoms of cholangiocarcinoma include [[jaundice]], [[pruritis]], [[abdominal pain]], [[weight loss]], [[fatigue]], and [[loss of appetite]].
The common symptoms of cholangiocarcinoma include [[jaundice]], [[pruritis]], [[abdominal pain]], [[weight loss]].


==Symptoms==
==History and Symptoms==
The most common symptom of cholangiocarcinoma is [[jaundice]] (yellowing of the eyes and skin), which occurs when bile ducts are blocked by the tumor. To some extent, the symptoms depend upon the location of the tumor. Patients with cholangiocarcinoma in the extrahepatic bile ducts (outside the liver) are more likely to have jaundice, while those with tumors of the [[bile ducts]] within the liver often have pain without jaundice.<ref name="nakeeb">{{cite journal |author=Nakeeb A, Pitt H, Sohn T, Coleman J, Abrams R, Piantadosi S, Hruban R, Lillemoe K, Yeo C, Cameron J |title=Cholangiocarcinoma. A spectrum of intrahepatic, perihilar, and distal tumors |journal=Ann Surg |volume=224 |issue=4 |pages=463–73; discussion 473-5 |year=1996 |id=PMID 8857851}}</ref> Other common symptoms include, in order of frequency:<ref>{{cite journal |author=Nagorney D, Donohue J, Farnell M, Schleck C, Ilstrup D |title=Outcomes after curative resetions of cholangiocarcinoma |journal=Arch Surg |volume=128 |issue=8 |pages=871–7; discussion 877-9 |year=1993 |id=PMID 8393652}}</ref>  
===Common Symptoms===
*[[pruritis|Generalized itching]] (66%)
Common symptoms of cholangiocarcinoma include:<ref name="pmid21460876">{{cite journal |vauthors=Patel T |title=Cholangiocarcinoma--controversies and challenges |journal=Nat Rev Gastroenterol Hepatol |volume=8 |issue=4 |pages=189–200 |year=2011 |pmid=21460876 |pmc=3888819 |doi=10.1038/nrgastro.2011.20 |url=}}</ref><ref name="pmid17457168">{{cite journal |vauthors=DeOliveira ML, Cunningham SC, Cameron JL, Kamangar F, Winter JM, Lillemoe KD, Choti MA, Yeo CJ, Schulick RD |title=Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution |journal=Ann. Surg. |volume=245 |issue=5 |pages=755–62 |year=2007 |pmid=17457168 |pmc=1877058 |doi=10.1097/01.sla.0000251366.62632.d3 |url=}}</ref>
*[[Abdominal pain]] (30% to 50%)
*[[Jaundice]]
*[[Weight loss]] (30% to 50%)
*[[Pruritis]]
*[[Fever]] (up to 20%)
*[[Abdominal pain]]  
*[[Fever]]  
*[[Fatigue]]
*[[Fatigue]]
===Less Common Symptoms===
Less common symptoms of cholangiocarcinoma include:<ref name="pmid17457168">{{cite journal |vauthors=DeOliveira ML, Cunningham SC, Cameron JL, Kamangar F, Winter JM, Lillemoe KD, Choti MA, Yeo CJ, Schulick RD |title=Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution |journal=Ann. Surg. |volume=245 |issue=5 |pages=755–62 |year=2007 |pmid=17457168 |pmc=1877058 |doi=10.1097/01.sla.0000251366.62632.d3 |url=}}</ref>
*[[Weight loss]]
*[[Loss of appetite]]
*[[Loss of appetite]]
<gallery>
*Clay-colored stools
PHIL 2860 lores.jpg|Yellowing of the skin and eyes (jaundice)
*Dark urine
</gallery>


==References==
==References==

Latest revision as of 19:40, 6 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Farima Kahe M.D. [2] Suveenkrishna Pothuru, M.B,B.S. [3]

Overview

The common symptoms of cholangiocarcinoma include jaundice, pruritis, abdominal pain, weight loss.

History and Symptoms

Common Symptoms

Common symptoms of cholangiocarcinoma include:[1][2]

Less Common Symptoms

Less common symptoms of cholangiocarcinoma include:[2]

References

  1. Patel T (2011). "Cholangiocarcinoma--controversies and challenges". Nat Rev Gastroenterol Hepatol. 8 (4): 189–200. doi:10.1038/nrgastro.2011.20. PMC 3888819. PMID 21460876.
  2. 2.0 2.1 DeOliveira ML, Cunningham SC, Cameron JL, Kamangar F, Winter JM, Lillemoe KD, Choti MA, Yeo CJ, Schulick RD (2007). "Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution". Ann. Surg. 245 (5): 755–62. doi:10.1097/01.sla.0000251366.62632.d3. PMC 1877058. PMID 17457168.

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