Cholangiocarcinoma risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2], Suveenkrishna Pothuru, M.B,B.S. [3]
Overview
Common risk factors in the development of cholangiocarcinoma include primary sclerosing cholangitis, fibropolycystic liver disease such as choledochal cysts, hepatolithiasis and recurrent pyogenic cholangitis.
Risk Factors
- Common risk factors in the development of cholangiocarcinoma include primary sclerosing cholangitis, fibropolycystic liver disease such as choledochal cysts, hepatolithiasis and recurrent pyogenic cholangitis.
Common Risk Factors
- Common risk factors in the development of cholangiocarcinoma include:[1][2][3][4][5]
- Primary sclerosing cholangitis
- Cirrhosis
- Viral infections
- Liver fluke infections
- Hepatolithiasis
- Choledochal cysts
- Infusion of certain chemical agents such as naphthenic acids
- Recurrent pyogenic cholangitis
- Opisthorchis viverrini
- Clonorchis sinensis
- Caroli's disease
- Inherited disorders
- Lynch syndrome
- Biliary papillomatosis
Less Common Risk Factors
- Less common risk factors in the development of cholangiocarcinoma include:[6]
- Thorotrast
- Diabetes
- Obesity
- Alcohol consumption
- Smoking
References
- ↑ Al-Bahrani R, Abuetabh Y, Zeitouni N, Sergi C (2013). "Cholangiocarcinoma: risk factors, environmental influences and oncogenesis". Ann. Clin. Lab. Sci. 43 (2): 195–210. PMID 23694797.
- ↑ Tyson GL, El-Serag HB (2011). "Risk factors for cholangiocarcinoma". Hepatology. 54 (1): 173–84. doi:10.1002/hep.24351. PMC 3125451. PMID 21488076.
- ↑ Ben-Menachem T (2007). "Risk factors for cholangiocarcinoma". Eur J Gastroenterol Hepatol. 19 (8): 615–7. doi:10.1097/MEG.0b013e328224b935. PMID 17625428.
- ↑ Gatto M, Alvaro D (2010). "Cholangiocarcinoma: risk factors and clinical presentation". Eur Rev Med Pharmacol Sci. 14 (4): 363–7. PMID 20496549.
- ↑ Acalovschi M (2004). "Cholangiocarcinoma: risk factors, diagnosis and management". Rom J Intern Med. 42 (1): 41–58. PMID 15529594.
- ↑ Razumilava N, Gores GJ (2013). "Classification, diagnosis, and management of cholangiocarcinoma". Clin. Gastroenterol. Hepatol. 11 (1): 13–21.e1, quiz e3–4. doi:10.1016/j.cgh.2012.09.009. PMC 3596004. PMID 22982100.