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Latest revision as of 17:19, 18 September 2017

Cat scratch fever Microchapters

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Overview

Historical Perspective

Pathophysiology

Differentiating Cat scratch fever from other Diseases

Epidemiology and Demographics

Risk Factors

Natural history, Complications and Prognosis

Diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

The majority of cases of cat scratch disease are self limited. Antimicrobial therapy is administered in select cases and the drug of choice is Azithromycin.

Medical Therapy

Most healthy people will clear the infection without treatment, and antimicrobial therapy is not recommended for immunocompetent patients with mild to moderate Bartonella henselae disease due to the risk of side-effects from antibiotics. Azithromycin, Ciprofloxacin, Doxycycline, and multiple other antibiotics have been used but with unclear benefit.[1]

  • Cat scratch disease[2]
  • Cat scratch disease in patients > 45 kg
  • Preferred regimen: Azithromycin 500 mg PO on day 1 AND 250 mg PO for additional 4 days
  • Cat scratch disease in patients < 45 kg
  • Preferred regimen: Azithromycin 10 mg/kg PO on day 1 AND 5 mg/kg PO for 4 more days

References

  1. Rolain, J.M. (2004). "Recommendations for Treatment of Human Infections Caused by Bartonella Species". Antimicrobial Agents and chemotherapy. 48 (6): 1921–1933. doi:10.1128/AAC.48.6.1921-1933.2004. PMC 415619. PMID 15155180. Unknown parameter |month= ignored (help)
  2. Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL; et al. (2014). "Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America". Clin Infect Dis. 59 (2): 147–59. doi:10.1093/cid/ciu296. PMID 24947530.

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