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'''Papillary fibroelastoma'''
'''Papillary fibroelastoma'''
:*[[primary tumors of the heart|Primary tumor of the heart]] that typically involves one of the valves of the [[heart]]
:*[[primary tumors of the heart|Primary tumor of the heart]] that typically involves one of the valves of the [[heart]]
:*Represent 10% of all primary tumors of the heart  
:*Papillary fibroelastoma is generally considered benign, and represents 10% of all primary tumors of the heart  
:*Papillary fibroelastoma are the third most common type of primary tumor of the heart, behind [[myxoma|cardiac myxomas]] and cardiac fibromas.<ref name="Matsumoto-2007">{{cite journal | author=Matsumoto N, Sato Y, Kusama J, Matsuo S, Kinukawa N, Kunimasa T, Ichiyama I, Takahashi H, Kimura S, Orime Y, Saito S. | title=Multiple papillary fibroelastomas of the aortic valve: case report. | journal=Int J Cardiol | year=2007 | volume=122 | issue=1 | pages=e1-3 | id=PMID 17196273}}</ref>
:*Papillary fibroelastoma are the third most common type of primary tumor of the heart, behind [[myxoma|cardiac myxomas]] and cardiac fibromas.<ref name="Matsumoto-2007">{{cite journal | author=Matsumoto N, Sato Y, Kusama J, Matsuo S, Kinukawa N, Kunimasa T, Ichiyama I, Takahashi H, Kimura S, Orime Y, Saito S. | title=Multiple papillary fibroelastomas of the aortic valve: case report. | journal=Int J Cardiol | year=2007 | volume=122 | issue=1 | pages=e1-3 | id=PMID 17196273}}</ref>
:*The pathogenesis of papillary fibroelastoma is characterised by the mechanical effects of the tumor and the transient occlusion of the [[left coronary artery|left main coronary artery]] (by the tumor), while a heart attack or sudden cardiac death may be due to embolisation of a portion of the tumor into a coronary artery.<ref name="Takada-2000">{{cite journal | author=Takada A, Saito K, Ro A, Tokudome S, Murai T. | title= Papillary fibroelastoma of the aortic valve: a sudden death case of coronary embolism with myocardial infarction.| journal=Forensic Sci Int | year=2000 | volume=113 | issue=1-3 | pages=209-14 | id=PMID 10978627}}</ref>


===Gross Pathology===
===Gross Pathology===

Revision as of 14:09, 2 May 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Varun Kumar, M.B.B.S.

Overview

Pathophysiology

Papillary fibroelastoma

  • Primary tumor of the heart that typically involves one of the valves of the heart
  • Papillary fibroelastoma is generally considered benign, and represents 10% of all primary tumors of the heart
  • Papillary fibroelastoma are the third most common type of primary tumor of the heart, behind cardiac myxomas and cardiac fibromas.[1]
  • The pathogenesis of papillary fibroelastoma is characterised by the mechanical effects of the tumor and the transient occlusion of the left main coronary artery (by the tumor), while a heart attack or sudden cardiac death may be due to embolisation of a portion of the tumor into a coronary artery.[2]

Gross Pathology

Image shown below is courtesy of Professor Peter Anderson DVM PhD and published with permission. © PEIR, University of Alabama at Birmingham, Department of Pathology




References

  1. Matsumoto N, Sato Y, Kusama J, Matsuo S, Kinukawa N, Kunimasa T, Ichiyama I, Takahashi H, Kimura S, Orime Y, Saito S. (2007). "Multiple papillary fibroelastomas of the aortic valve: case report". Int J Cardiol. 122 (1): e1–3. PMID 17196273.
  2. Takada A, Saito K, Ro A, Tokudome S, Murai T. (2000). "Papillary fibroelastoma of the aortic valve: a sudden death case of coronary embolism with myocardial infarction". Forensic Sci Int. 113 (1–3): 209–14. PMID 10978627.

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