CMV pneumonitis

CMV pneumonitis

CMV pneumonitis Microchapters
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Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating CMV pneumonitis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
CMV pneumonitis On the Web
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American Roentgen Ray Society Images of CMV pneumonitis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on CMV pneumonitis
CDC on CMV pneumonitis
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Blogs on CMV pneumonitis
Directions to Hospitals Treating CMV pneumonitis
Risk calculators and risk factors for CMV pneumonitis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Diagnosis

History and Symptoms | Physical Examination | Staging | Laboratory tests | Electrocardiogram | X Rays | CT | MRI Echocardiography or Ultrasound | Other images | Alternative diagnostics

Treatment

Medical therapy | Surgical options | Primary prevention | Secondary prevention | Financial costs | Future therapies

Treatment

Pharmacotherapy

• Treatment is most commonly with ganciclovir 5 mg/kg q12h, though results are disappointing. BMT patients characteristically respond, but clinical response is quite variable in AIDS patients, inconsistently showing a significant benefit in different studies.

Transplantation

• Prophylaxis is now being used at some transplant centers. Options include CMV hyperimmune globulin or antiviral treatment such as ganciclovir.

Future or Investigational Therapies

• Trials of ganciclovir with CMV IgG have not shown a consistent benefit in all studies.
• Foscarnet is an alternative agent but data on its efficacy is lacking

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