CMV pneumonitis natural history

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

CMV pneumonitis Microchapters
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Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating CMV pneumonitis from other Diseases
Epidemiology and Demographics
Risk Factors
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Natural History, Complications and Prognosis
Diagnosis
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History and Symptoms
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Complications

Complications of CMV infection in people with AIDS include:

• CMV pneumonia.
• Esophageal disease.
• Intestinal disease.
• Infectious, mononucleosis-like illness (CMV mononucleosis).
• Inflammation of the retina (CMV retinitis).

Complications of CMV pneumonia include:

• Kidney impairment (from drugs used to treat the condition).
• Low white blood cell count (from drugs used to treat the condition).
• Overwhelming infection that doesn't respond to treatment.
• Return of infections.

Prognosis

Prognosis is poor. Particularly in significantly immunocompromised hosts, mortality from significant CMV pneumonitis may be greater than 50%.