CDH3 (gene): Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Cadherin-3''', also known as '''P-Cadherin''', is a [[protein]] that in humans is encoded by the ''CDH3'' [[gene]].<ref name="pmid1427864">{{cite journal | vauthors = Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A | title = The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species | journal = Genomics | volume = 14 | issue = 2 | pages = 488–90 | date = Oct 1992 | pmid = 1427864 | pmc =  | doi = 10.1016/S0888-7543(05)80247-2 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CDH3 cadherin 3, type 1, P-cadherin (placental)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1001| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Cadherin 3, type 1, P-cadherin (placental)
| HGNCid = 1762
| Symbol = CDH3
| AltSymbols =; CDHP; HJMD; PCAD
| OMIM = 114021
| ECnumber = 
| Homologene = 20425
| MGIid = 88356
| GeneAtlas_image1 = PBB_GE_CDH3_203256_at_tn.png
| Function = {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007155 |text = cell adhesion}} {{GNF_GO|id=GO:0007156 |text = homophilic cell adhesion}} {{GNF_GO|id=GO:0007601 |text = visual perception}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 1001
    | Hs_Ensembl = ENSG00000062038
    | Hs_RefseqProtein = NP_001784
    | Hs_RefseqmRNA = NM_001793
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 67236240
    | Hs_GenLoc_end = 67290440
    | Hs_Uniprot = P22223
    | Mm_EntrezGene = 12560
    | Mm_Ensembl = ENSMUSG00000061048
    | Mm_RefseqmRNA = XM_001000165
    | Mm_RefseqProtein = XP_001000165
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 8
    | Mm_GenLoc_start = 109400042
    | Mm_GenLoc_end = 109446037
    | Mm_Uniprot = Q80VY6
  }}
}}
'''Cadherin 3, type 1, P-cadherin (placental)''', also known as '''CDH3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CDH3 cadherin 3, type 1, P-cadherin (placental)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1001| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene is a classical [[cadherin]] from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved [[Cadherin cytoplasmic region|cytoplasmic tail]]. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas.
{{PBB_Summary
| section_title =
| summary_text = This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.<ref name="entrez">{{cite web | title = Entrez Gene: CDH3 cadherin 3, type 1, P-cadherin (placental)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1001| accessdate = }}</ref>
}}


==References==
== Clinical significance ==
{{reflist|2}}
 
==Further reading==
Mutations in this gene have been associated with congenital [[hypotrichosis with juvenile macular dystrophy]].<ref name="entrez"/>
{{refbegin | 2}}
 
{{PBB_Further_reading
== Interactions ==
| citations =
 
*{{cite journal | author=Kaupmann K, Becker-Follmann J, Scherer G, ''et al.'' |title=The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species. |journal=Genomics |volume=14 |issue= 2 |pages= 488-90 |year= 1992 |pmid= 1427864 |doi= }}
CDH3 (gene) has been shown to [[Protein-protein interaction|interact]] with:
*{{cite journal | author=Herrenknecht K, Ozawa M, Eckerskorn C, ''et al.'' |title=The uvomorulin-anchorage protein alpha catenin is a vinculin homologue. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 20 |pages= 9156-60 |year= 1991 |pmid= 1924379 |doi=  }}
* [[Beta-catenin]],<ref name = pmid10910767/><ref name = pmid10381631>{{cite journal | vauthors = Schmeiser K, Grand RJ | title = The fate of E- and P-cadherin during the early stages of apoptosis | journal = Cell Death and Differentiation | volume = 6 | issue = 4 | pages = 377–86 | date = Apr 1999 | pmid = 10381631 | doi = 10.1038/sj.cdd.4400504 }}</ref>
*{{cite journal | author=Shimoyama Y, Hirohashi S, Hirano S, ''et al.'' |title=Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. |journal=Cancer Res. |volume=49 |issue= 8 |pages= 2128-33 |year= 1989 |pmid= 2702654 |doi= }}
* [[CDH1 (gene)|CDH1]],<ref name = pmid10910767>{{cite journal | vauthors = Klingelhöfer J, Troyanovsky RB, Laur OY, Troyanovsky S | title = Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions | journal = Journal of Cell Science | volume = 113 | issue = 16| pages = 2829–36 | date = Aug 2000 | pmid = 10910767 | doi =  }}</ref>
*{{cite journal  | author=Shimoyama Y, Yoshida T, Terada M, ''et al.'' |title=Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues. |journal=J. Cell Biol. |volume=109 |issue= 4 Pt 1 |pages= 1787-94 |year= 1989 |pmid= 2793940 |doi= }}
* [[Catenin (cadherin-associated protein), alpha 1]],<ref name = pmid10910767/><ref name = pmid10381631/>
*{{cite journal | author=Palacios J, Benito N, Pizarro A, ''et al.'' |title=Anomalous expression of P-cadherin in breast carcinoma. Correlation with E-cadherin expression and pathological features. |journal=Am. J. Pathol. |volume=146 |issue= 3 |pages= 605-12 |year= 1995 |pmid= 7534041 |doi=  }}
* [[Nephrin]]<ref name = pmid15331416>{{cite journal | vauthors = Lehtonen S, Lehtonen E, Kudlicka K, Holthöfer H, Farquhar MG | title = Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin | journal = The American Journal of Pathology | volume = 165 | issue = 3 | pages = 923–36 | date = Sep 2004 | pmid = 15331416 | pmc = 1618613 | doi = 10.1016/S0002-9440(10)63354-8 }}</ref>  and
*{{cite journal | author=van der Linden PJ, de Goeij AF, Dunselman GA, ''et al.'' |title=Expression of cadherins and integrins in human endometrium throughout the menstrual cycle. |journal=Fertil. Steril. |volume=63 |issue= 6 |pages= 1210-6 |year= 1995 |pmid= 7538474 |doi= }}
* [[Plakoglobin]].<ref name = pmid10910767/>
*{{cite journal | author=Tang A, Eller MS, Hara M, ''et al.'' |title=E-cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro. |journal=J. Cell. Sci. |volume=107 ( Pt 4) |issue= |pages= 983-92 |year= 1994 |pmid= 8056851 |doi=  }}
 
*{{cite journal | author=Tassin MT, Beziau A, Gubler MC, Boyer B |title=Spatiotemporal expression of molecules associated with junctional complexes during the in vivo maturation of renal podocytes. |journal=Int. J. Dev. Biol. |volume=38 |issue= 1 |pages= 45-54 |year= 1994 |pmid= 8074995 |doi=  }}
== See also ==
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
* [[EEM syndrome]]
*{{cite journal | author=Navarro P, Lozano E, Cano A |title=Expression of E- or P-cadherin is not sufficient to modify the morphology and the tumorigenic behavior of murine spindle carcinoma cells. Possible involvement of plakoglobin. |journal=J. Cell. Sci. |volume=105 ( Pt 4) |issue= |pages= 923-34 |year= 1993 |pmid= 8227214 |doi=  }}
 
*{{cite journal | author=Reynolds AB, Daniel JM, Mo YY, ''et al.'' |title=The novel catenin p120cas binds classical cadherins and induces an unusual morphological phenotype in NIH3T3 fibroblasts. |journal=Exp. Cell Res. |volume=225 |issue= 2 |pages= 328-37 |year= 1996 |pmid= 8660921 |doi= 10.1006/excr.1996.0183 }}
== References ==
*{{cite journal | author=Soler AP, Harner GD, Knudsen KA, ''et al.'' |title=Expression of P-cadherin identifies prostate-specific-antigen-negative cells in epithelial tissues of male sexual accessory organs and in prostatic carcinomas. Implications for prostate cancer biology. |journal=Am. J. Pathol. |volume=151 |issue= 2 |pages= 471-8 |year= 1997 |pmid= 9250159 |doi=  }}
{{reflist|33em}}
*{{cite journal | author=Wakita H, Furukawa F, Baba S, Takigawa M |title=Human squamous-cell-carcinoma cell line (DJM-1) cells synthesize P-cadherin molecules via an elevation of extracellular calcium: calcium regulates P-cadherin-gene expression at the translational level via protein tyrosine phosphorylation. |journal=Int. J. Cancer |volume=73 |issue= 3 |pages= 432-9 |year= 1997 |pmid= 9359492 |doi= }}
 
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
== Further reading ==
*{{cite journal | author=Kremmidiotis G, Baker E, Crawford J, ''et al.'' |title=Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. |journal=Genomics |volume=49 |issue= 3 |pages= 467-71 |year= 1998 |pmid= 9615235 |doi= 10.1006/geno.1998.5281 }}
{{refbegin|33em}}
*{{cite journal | author=Jarrard DF, Paul R, van Bokhoven A, ''et al.'' |title=P-Cadherin is a basal cell-specific epithelial marker that is not expressed in prostate cancer. |journal=Clin. Cancer Res. |volume=3 |issue= 11 |pages= 2121-8 |year= 1999 |pmid= 9815605 |doi= }}
* {{cite journal | vauthors = Herrenknecht K, Ozawa M, Eckerskorn C, Lottspeich F, Lenter M, Kemler R | title = The uvomorulin-anchorage protein alpha catenin is a vinculin homologue | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 88 | issue = 20 | pages = 9156–60 | date = Oct 1991 | pmid = 1924379 | pmc = 52671 | doi = 10.1073/pnas.88.20.9156 }}
*{{cite journal | author=Schmeiser K, Grand RJ |title=The fate of E- and P-cadherin during the early stages of apoptosis. |journal=Cell Death Differ. |volume=6 |issue= 4 |pages= 377-86 |year= 1999 |pmid= 10381631 |doi= 10.1038/sj.cdd.4400504 }}
* {{cite journal | vauthors = Shimoyama Y, Hirohashi S, Hirano S, Noguchi M, Shimosato Y, Takeichi M, Abe O | title = Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas | journal = Cancer Research | volume = 49 | issue = 8 | pages = 2128–33 | date = Apr 1989 | pmid = 2702654 | doi =  }}
*{{cite journal | author=Rufas O, Fisch B, Ziv S, Shalgi R |title=Expression of cadherin adhesion molecules on human gametes. |journal=Mol. Hum. Reprod. |volume=6 |issue= 2 |pages= 163-9 |year= 2000 |pmid= 10655458 |doi=  }}
* {{cite journal | vauthors = Shimoyama Y, Yoshida T, Terada M, Shimosato Y, Abe O, Hirohashi S | title = Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues | journal = The Journal of Cell Biology | volume = 109 | issue = 4 Pt 1 | pages = 1787–94 | date = Oct 1989 | pmid = 2793940 | pmc = 2115800 | doi = 10.1083/jcb.109.4.1787 }}
*{{cite journal | author=Klingelhöfer J, Troyanovsky RB, Laur OY, Troyanovsky S |title=Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions. |journal=J. Cell. Sci. |volume=113 ( Pt 16) |issue= |pages= 2829-36 |year= 2000 |pmid= 10910767 |doi= }}
* {{cite journal | vauthors = Palacios J, Benito N, Pizarro A, Suárez A, Espada J, Cano A, Gamallo C | title = Anomalous expression of P-cadherin in breast carcinoma. Correlation with E-cadherin expression and pathological features | journal = The American Journal of Pathology | volume = 146 | issue = 3 | pages = 605–12 | date = Mar 1995 | pmid = 7534041 | pmc = 1869170 | doi =  }}
*{{cite journal | author=Han AC, Edelson MI, Peralta Soler A, ''et al.'' |title=Cadherin expression in glandular tumors of the cervix. |journal=Cancer |volume=89 |issue= 10 |pages= 2053-8 |year= 2000 |pmid= 11066045 |doi= }}
* {{cite journal | vauthors = van der Linden PJ, de Goeij AF, Dunselman GA, Erkens HW, Evers JL | title = Expression of cadherins and integrins in human endometrium throughout the menstrual cycle | journal = Fertility and Sterility | volume = 63 | issue = 6 | pages = 1210–6 | date = Jun 1995 | pmid = 7538474 | doi =  10.1016/s0015-0282(16)57599-2}}
}}
* {{cite journal | vauthors = Tang A, Eller MS, Hara M, Yaar M, Hirohashi S, Gilchrest BA | title = E-cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro | journal = Journal of Cell Science | volume = 107 | issue = 4 | pages = 983–92 | date = Apr 1994 | pmid = 8056851 | doi =  }}
* {{cite journal | vauthors = Tassin MT, Beziau A, Gubler MC, Boyer B | title = Spatiotemporal expression of molecules associated with junctional complexes during the in vivo maturation of renal podocytes | journal = The International Journal of Developmental Biology | volume = 38 | issue = 1 | pages = 45–54 | date = Mar 1994 | pmid = 8074995 | doi =  }}
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = Jan 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
* {{cite journal | vauthors = Navarro P, Lozano E, Cano A | title = Expression of E- or P-cadherin is not sufficient to modify the morphology and the tumorigenic behavior of murine spindle carcinoma cells. Possible involvement of plakoglobin | journal = Journal of Cell Science | volume = 105 | issue = 4 | pages = 923–34 | date = Aug 1993 | pmid = 8227214 | doi =  }}
* {{cite journal | vauthors = Reynolds AB, Daniel JM, Mo YY, Wu J, Zhang Z | title = The novel catenin p120cas binds classical cadherins and induces an unusual morphological phenotype in NIH3T3 fibroblasts | journal = Experimental Cell Research | volume = 225 | issue = 2 | pages = 328–37 | date = Jun 1996 | pmid = 8660921 | doi = 10.1006/excr.1996.0183 }}
* {{cite journal | vauthors = Soler AP, Harner GD, Knudsen KA, McBrearty FX, Grujic E, Salazar H, Han AC, Keshgegian AA | title = Expression of P-cadherin identifies prostate-specific-antigen-negative cells in epithelial tissues of male sexual accessory organs and in prostatic carcinomas. Implications for prostate cancer biology | journal = The American Journal of Pathology | volume = 151 | issue = 2 | pages = 471–8 | date = Aug 1997 | pmid = 9250159 | pmc = 1858007 | doi =  }}
* {{cite journal | vauthors = Wakita H, Furukawa F, Baba S, Takigawa M | title = Human squamous-cell-carcinoma cell line (DJM-1) cells synthesize P-cadherin molecules via an elevation of extracellular calcium: calcium regulates P-cadherin-gene expression at the translational level via protein tyrosine phosphorylation | journal = International Journal of Cancer | volume = 73 | issue = 3 | pages = 432–9 | date = Nov 1997 | pmid = 9359492 | doi = 10.1002/(SICI)1097-0215(19971104)73:3<432::AID-IJC19>3.0.CO;2-E }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = Oct 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
* {{cite journal | vauthors = Kremmidiotis G, Baker E, Crawford J, Eyre HJ, Nahmias J, Callen DF | title = Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity | journal = Genomics | volume = 49 | issue = 3 | pages = 467–71 | date = May 1998 | pmid = 9615235 | doi = 10.1006/geno.1998.5281 }}
* {{cite journal | vauthors = Jarrard DF, Paul R, van Bokhoven A, Nguyen SH, Bova GS, Wheelock MJ, Johnson KR, Schalken J, Bussemakers M, Isaacs WB | title = P-Cadherin is a basal cell-specific epithelial marker that is not expressed in prostate cancer | journal = Clinical Cancer Research | volume = 3 | issue = 11 | pages = 2121–8 | date = Nov 1997 | pmid = 9815605 | doi =  }}
* {{cite journal | vauthors = Schmeiser K, Grand RJ | title = The fate of E- and P-cadherin during the early stages of apoptosis | journal = Cell Death and Differentiation | volume = 6 | issue = 4 | pages = 377–86 | date = Apr 1999 | pmid = 10381631 | doi = 10.1038/sj.cdd.4400504 }}
* {{cite journal | vauthors = Rufas O, Fisch B, Ziv S, Shalgi R | title = Expression of cadherin adhesion molecules on human gametes | journal = Molecular Human Reproduction | volume = 6 | issue = 2 | pages = 163–9 | date = Feb 2000 | pmid = 10655458 | doi = 10.1093/molehr/6.2.163 }}
* {{cite journal | vauthors = Klingelhöfer J, Troyanovsky RB, Laur OY, Troyanovsky S | title = Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions | journal = Journal of Cell Science | volume = 113 | issue = 16 | pages = 2829–36 | date = Aug 2000 | pmid = 10910767 | doi =  }}
* {{cite journal | vauthors = Han AC, Edelson MI, Peralta Soler A, Knudsen KA, Lifschitz-Mercer B, Czernobilsky B, Rosenblum NG, Salazar H | title = Cadherin expression in glandular tumors of the cervix | journal = Cancer | volume = 89 | issue = 10 | pages = 2053–8 | date = Nov 2000 | pmid = 11066045 | doi = 10.1002/1097-0142(20001115)89:10<2053::AID-CNCR4>3.0.CO;2-C }}
* {{cite journal | vauthors = Bauer K, Gosau M, Reinders J, Oefner P, Reichert TE, Bauer R | title = Presenilin 1/γ-secretase modulates P-cadherin processing and influences cell adhesion in oral squamous cell carcinoma cell lines | journal = Carcinogenesis | volume = 34 | issue = 11 | pages = 2622–8 | date = Nov 2013 | pmid = 23740836 | doi = 10.1093/carcin/bgt211 }}
{{refend}}
{{refend}}


{{protein-stub}}
== External links ==
{{WikiDoc Sources}}
* {{UCSC genome browser|CDH3}}
* {{UCSC gene details|CDH3}}
 
{{Cell adhesion molecules}}
 
 
{{gene-16-stub}}

Latest revision as of 21:55, 25 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Cadherin-3, also known as P-Cadherin, is a protein that in humans is encoded by the CDH3 gene.[1][2]

Function

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas.

Clinical significance

Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.[2]

Interactions

CDH3 (gene) has been shown to interact with:

See also

References

  1. ↑ Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (Oct 1992). "The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species". Genomics. 14 (2): 488–90. doi:10.1016/S0888-7543(05)80247-2. PMID 1427864.
  2. ↑ 2.0 2.1 "Entrez Gene: CDH3 cadherin 3, type 1, P-cadherin (placental)".
  3. ↑ 3.0 3.1 3.2 3.3 Klingelhöfer J, Troyanovsky RB, Laur OY, Troyanovsky S (Aug 2000). "Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions". Journal of Cell Science. 113 (16): 2829–36. PMID 10910767.
  4. ↑ 4.0 4.1 Schmeiser K, Grand RJ (Apr 1999). "The fate of E- and P-cadherin during the early stages of apoptosis". Cell Death and Differentiation. 6 (4): 377–86. doi:10.1038/sj.cdd.4400504. PMID 10381631.
  5. ↑ Lehtonen S, Lehtonen E, Kudlicka K, Holthöfer H, Farquhar MG (Sep 2004). "Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin". The American Journal of Pathology. 165 (3): 923–36. doi:10.1016/S0002-9440(10)63354-8. PMC 1618613. PMID 15331416.

Further reading

External links


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