Aortic coarctation epidemiology and demographics: Difference between revisions

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{{Aortic Coarctation}}
{{Aortic Coarctation}}
{{CMG}}
{{CMG}}; '''Associate Editor(s)-In-Chief:''' {{CZ}}, [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]][mailto:psingh13579@gmail.com]
 
'''Associate Editor-in-Chief:''' {{CZ}}
 
==Overview==
==Overview==
Coarctation occurs in about 7% of patients with congenital heart defects.  It is more common in males than females with a ratio of 2:1. Up to 25% of patients with [[Turner syndrome]] have coarctation of the aorta.
Coarctation of the aorta is a common congenital malformation. It occurs in about 7% of patients with [[congenital heart defect]]s.  It is more common in males than females with a ratio of 2:1. Up to 25% of patients with [[Turner syndrome]] have coarctation of the aorta. It is 7 times more common among caucasians than asians.


==Epidemiology and demographics==
==Epidemiology and Demographics==
* [[Aortic coarctation]] is a common congenital heart defect. While statistics vary across research, aortic coarctation occurs in approximately 6-10% of all congenital heart disease cases. In live births, aortic coarctation accounts for approximately 5-7% of congenital heart disease in severely ill infants.
===Age===
* The diagnosis is often missed in first year of life.
* Generally, patients with coarctation of the aorta present early in life with [[congestive heart failure]] or later in life with [[hypertension]].
===Gender===
* It is 2 times more common in males than females.


* The mortality rate of aortic coarctation hinges primarily on the age of surgical intervention to repair the defect. Left untreated, less than 20% of untreated patients reach the age of 50. However, with surgical repair, mortality rates are far less severe. If repaired by the age of 14, the mortality rate for 20 years out post-surgery is 9% (a 91% survival rate). If repaired later than 14, the mortality rate is 11% (a 79% survival rate).
===Race===
* Coarctation is 7 times more common among Caucasians than Asians.
* The [[incidence]] is lower in Native Americans than Caucasians.
===United States of America===
* [[Aortic coarctation]] is a common heart defect.
* It forms approximately 6-10% of all [[congenital heart disease]] cases.
* In live births, it accounts for approximately 5-7% of [[congenital heart disease]] in severely ill [[infants]].


* In expectant mothers with a coarctation of the aorta, the maternal mortality rate ranges between 3-8%. Even with repair, there is a risk of developing complications during pregnancy.
===International===
===Race===
* The prevalence is lower in Asian countries compared to American and European countries.
* Demographically, aortic coarctation has a certain link to specific races.
* Aortic coarctation is more common in Caucasians, with approximately 7 times more cases in Caucasians versus Asian.
* The incidence has also been noted, in some populations, to be lower in Native American races than Caucasians.
===Gender===
* It is more common in males than females with a ratio of 2:1 and a prevalence of 2-5 times occurring more frequently in males than females.
===Genetics===
* Aortic coarctation, like many congenital heart diseases, is more common in patients with other genetic conditions.
* As many as 10-25% of patients with [[Turner syndrome]] have an accompanying coarctation of the aorta.
* Other accompanying conditions, that increase the likelihood of a coarctation of the aorta, include:
** [[Ventricular septal defect]]
** [[Patent ductus arteriosus]]
** Mitral valve stenosis
** [[Aortic valve stenosis]]
** [[Bicuspid aortic valve]] - associated to 30-40% of all cases


==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[CME Category::Cardiology]]


[[Category:Cardiology]]
[[Category:Cardiology]]

Latest revision as of 22:16, 14 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Priyamvada Singh, M.B.B.S.[3]

Overview

Coarctation of the aorta is a common congenital malformation. It occurs in about 7% of patients with congenital heart defects. It is more common in males than females with a ratio of 2:1. Up to 25% of patients with Turner syndrome have coarctation of the aorta. It is 7 times more common among caucasians than asians.

Epidemiology and Demographics

Age

  • The diagnosis is often missed in first year of life.
  • Generally, patients with coarctation of the aorta present early in life with congestive heart failure or later in life with hypertension.

Gender

  • It is 2 times more common in males than females.

Race

  • Coarctation is 7 times more common among Caucasians than Asians.
  • The incidence is lower in Native Americans than Caucasians.

United States of America

International

  • The prevalence is lower in Asian countries compared to American and European countries.

References

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