Amoxicillin: Difference between revisions
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'''Amoxicillin''' ([[International Nonproprietary Name|INN]]), formerly '''amoxycillin''' ([[British Approved Name|BAN]]), and abbreviated '''amox''', is a moderate-spectrum, bacteriolytic, [[beta-lactam antibiotic|β-lactam]] [[antibiotic]] used to treat [[bacterial]] [[infection]]s caused by susceptible [[microorganism]]s. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is one of the most common [[antibiotic]]s prescribed for children. The drug first became available in [[Timeline of antibiotics|1972]]. | '''Amoxicillin''' ([[International Nonproprietary Name|INN]]), formerly '''amoxycillin''' ([[British Approved Name|BAN]]), and abbreviated '''amox''', is a moderate-spectrum, bacteriolytic, [[beta-lactam antibiotic|β-lactam]] [[antibiotic]] used to treat [[bacterial]] [[infection]]s caused by susceptible [[microorganism]]s. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is one of the most common [[antibiotic]]s prescribed for children. The drug first became available in [[Timeline of antibiotics|1972]]. | ||
Amoxicillin is susceptible to degradation by [[beta-lactamase|β-lactamase]]-producing bacteria, which are resistant to a broad spectrum of β-lactam antibiotics, such as penicillin. For this reason, it is often combined with [[clavulanic acid]], a β-lactamase inhibitor. This increases effectiveness by reducing its susceptibility to β-lactamase resistance.<ref>{{cite web|title=Amoxicillin Susceptibility and Resistance Data|url=http://www.toku-e.com/Assets/MIC/AmoxicillinClavulanate%20augmentin.pdf|accessdate | Amoxicillin is susceptible to degradation by [[beta-lactamase|β-lactamase]]-producing bacteria, which are resistant to a broad spectrum of β-lactam antibiotics, such as penicillin. For this reason, it is often combined with [[clavulanic acid]], a β-lactamase inhibitor. This increases effectiveness by reducing its susceptibility to β-lactamase resistance.<ref>{{cite web|title=Amoxicillin Susceptibility and Resistance Data|url=http://www.toku-e.com/Assets/MIC/AmoxicillinClavulanate%20augmentin.pdf|accessdate}}</ref> | ||
==Category== | ==Category== | ||
Revision as of 02:24, 22 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Amoxicillin (INN), formerly amoxycillin (BAN), and abbreviated amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is one of the most common antibiotics prescribed for children. The drug first became available in 1972.
Amoxicillin is susceptible to degradation by β-lactamase-producing bacteria, which are resistant to a broad spectrum of β-lactam antibiotics, such as penicillin. For this reason, it is often combined with clavulanic acid, a β-lactamase inhibitor. This increases effectiveness by reducing its susceptibility to β-lactamase resistance.[1]
Category
US Brand Names
MOXATAG®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Dosage and Administration | How Supplied
Mechanism of Action
Amoxicillin is similar to ampicillin in its bactericidal action against susceptible organisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell wall mucopeptide.
References
- ↑ "Amoxicillin Susceptibility and Resistance Data" (PDF). Text "accessdate" ignored (help)