Amoxicillin: Difference between revisions
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==Overview== | ==Overview== | ||
'''Amoxicillin''' ([[International Nonproprietary Name|INN]]), formerly '''amoxycillin''' ([[British Approved Name|BAN]]), and abbreviated '''amox''', is a moderate-spectrum, bacteriolytic, [[beta-lactam antibiotic|β-lactam]] [[antibiotic]] used to treat [[bacterial]] [[infection]]s caused by susceptible [[microorganism]]s. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is one of the most common [[antibiotic]]s prescribed for children. The drug first became available in [[Timeline of antibiotics|1972]]. | |||
Amoxicillin is susceptible to degradation by [[beta-lactamase|β-lactamase]]-producing bacteria, which are resistant to a broad spectrum of β-lactam antibiotics, such as [[penicillin]]. For this reason, it is often combined with [[clavulanic acid]], a β-lactamase inhibitor. This increases effectiveness by reducing its susceptibility to β-lactamase resistance.<ref>{{cite web|title=Amoxicillin Susceptibility and Resistance Data|url=http://www.toku-e.com/Assets/MIC/AmoxicillinClavulanate%20augmentin.pdf|accessdate=20 July 2013}}</ref> | |||
==Category== | ==Category== | ||
Revision as of 15:35, 27 December 2013
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Amoxicillin (INN), formerly amoxycillin (BAN), and abbreviated amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is one of the most common antibiotics prescribed for children. The drug first became available in 1972.
Amoxicillin is susceptible to degradation by β-lactamase-producing bacteria, which are resistant to a broad spectrum of β-lactam antibiotics, such as penicillin. For this reason, it is often combined with clavulanic acid, a β-lactamase inhibitor. This increases effectiveness by reducing its susceptibility to β-lactamase resistance.[1]
Category
US Brand Names
MOXATAG®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | Compatibility, Reconstitution, and Stability | Directions For Use | How Supplied | Labels and Packages
Mechanism of Action
References
- ↑ "Amoxicillin Susceptibility and Resistance Data" (PDF). Retrieved 20 July 2013.