Amnesia historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zehra Malik, M.B.B.S[2]

Historical Perspective

  • Richard Semon in 1904 described that experiences cause some changes in the neurons and these changes are referred to as engram and they form memory of the particular experience in those neurons. Reactivation of these neurons occur when patient tries to recall those memories.[1]
  • In 1763, Sauvages recognized amnesia as a medical disorder.[2]
  • In early 19th century clinical description of amnesia was identified.[2]
  • Caroline Miles and Henri & Henri first described infantile amnesia in 1893 and 1895,respectively. It was further explained by Sigmund Freud in 1953.[3]
  • Alzheimer's disease was first described in 1906 by Alois Alzheimer, a psychiatrist and a pathologist of German origin.

References

  1. Semon R. (1904). Die mneme [The mneme]. Edited by W. Engelmann. Leipzig
  2. 2.0 2.1 Langer KG (2019). "Early History of Amnesia". Front Neurol Neurosci. 44: 64–74. doi:10.1159/000494953. PMID 31220849.
  3. Alberini CM, Travaglia A (2017). "Infantile Amnesia: A Critical Period of Learning to Learn and Remember". J Neurosci. 37 (24): 5783–5795. doi:10.1523/JNEUROSCI.0324-17.2017. PMC 5473198. PMID 28615475.

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