Alcoholic hepatitis history and symptoms: Difference between revisions

Jump to navigation Jump to search
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Alcoholic hepatitis}}
{{Alcoholic hepatitis}}
{{CMG}}; '''Assosciate Editor(s)-In-Chief:''' [[User: Prashanthsaddala|Prashanth Saddala M.B.B.S]]
{{CMG}}; {{AE}} {{S.M}}
==Overview==
[[Alcoholic Hepatitis]] is suspected to occur in [[patients]] with excessive [[drinking]] over the [[decades]].[[Symptoms]] of [[Alcoholic hepatitis]] can vary from [[mild]]  to [[severe]].The symptoms include [[nausea]],[[malaise]], low-grade [[fever]], [[abdominal Pain]], yellow discoloration of [[skin]] increased [[abdominal]] girth due to [[ascites]], [[gastrointestinal]] [[bleeding]] due to variceal [[hemorrhage]], [[lack of appetite]], [[confusion]], and [[lethargy]].


==History==
==History==
Denial is an important component of alcoholism, so appropriate questioning and honest responses are necessary to ascertain the appropriate history. ''CAGE'' questioning (''C''ut down, ''A''nnoyed, ''G''uilty, ''E''ye opener) has been shown to be useful in predicting significant alcoholism.
*[[Alcoholic Hepatitis]] occurs in [[patients]] with excessive [[drinking]] over the [[decades]]
* [[Alcoholic Hepatitis]] can also occur after short period of [[drinking]] 100 g [[alcohol]] daily.
* Heavy [[drinking]] is considered as [[drinking]] ≥15 drinks/week in [[men]] and ≥8 drinks/week in [[women]].
* [[Binge drinking]] is defined as consumption of ≥5 [[drinks]] in [[men]] and ≥ four [[drinks]] in [[women]] in 2 hours.
*According to National Institute on Alcohol Abuse and Alcoholism (NIAAA) states that consumption of > 3 drinks (approximately 40 g) per day in [[women]] and 4 drinks (approximately 60 g) per day in [[men]] is considered as threshold for [[Alcoholic Hepatitis]]<ref name="pmid27373612">{{cite journal| author=Dugum MF, McCullough AJ| title=Acute Alcoholic Hepatitis, the Clinical Aspects. | journal=Clin Liver Dis | year= 2016 | volume= 20 | issue= 3 | pages= 499-508 | pmid=27373612 | doi=10.1016/j.cld.2016.02.008 | pmc=6130321 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27373612  }} </ref>
 
==Symptoms==
==Symptoms==
Alcoholic hepatitis is characterized by a variable constellation of symptoms, which may include feeling unwell, enlargement of the liver, development of fluid in the abdomen [[ascites]], and modest elevation of liver blood tests.  Alcoholic hepatitis can vary from mild with only liver test elevation to severe liver inflammation with development of jaundice, prolonged [[prothrombin time]], and liver failure. Severe cases are characterized by either [[obtundation]] (dulled consciousness) or the combination of elevated [[bilirubin]] levels and prolonged prothrombin time; the mortality rate in both categories is 50% within 30 days of onset.
* [[Symptoms]] of [[Alcoholic hepatitis]] can vary from [[mild]]  to [[severe]]. The [[symptoms]] include:<ref> {{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK470217/ |title=Alcoholic Hepatitis - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref>
 
** [[Nausea]]
* [[Abdominal Pain|Abdominal pain]]--occurs in some, but should raise the suspicion for other processes, like [[Pancreatitis|pancreatitis]] or [[spontaneous bacterial peritonitis]] (SBP)
** [[Malaise]]
* Alcohol withdrawal
** Low-grade [[fever]]
* [[Ddx:Anorexia|Anorexia]]
** [[Abdominal Pain]]
* [[Ascites]]- Transient portal venous obstruction, in addition to fixed fibrosis, likely contributes, and so ascites may improve as hepatitis recovers
** Yellow discoloration of [[skin]]
* Bleeding
** Increased [[abdominal]] girth due to [[Ascites]]
* [[Encephalopathy]]
** [[Gastrointestinal]] [[bleeding]] due to variceal [[hemorrhage]]
* [[Ddx:Fever|Fever]]--if signficant, other sources should be ruled out
** [[Lack of appetite]]
* [[Ddx:Jaundice|Jaundice]]
** [[Confusion]]
* Many acute presentations occur in patients with some degree of chronic injury
** [[Lethargy]]
* [[Ddx:Nausea and Vomiting|Nausea and vomiting]]
* [[Ddx:Weight Loss|Weight loss]]


==References==
==References==

Latest revision as of 22:01, 2 August 2021

Alcoholic hepatitis Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Alcoholic hepatitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Alcoholic hepatitis history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Alcoholic hepatitis history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Alcoholic hepatitis history and symptoms

CDC on Alcoholic hepatitis history and symptoms

Alcoholic hepatitis history and symptoms in the news

Blogs on Alcoholic hepatitis history and symptoms

Directions to Hospitals Treating Alcoholic hepatitis

Risk calculators and risk factors for Alcoholic hepatitis history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Overview

Alcoholic Hepatitis is suspected to occur in patients with excessive drinking over the decades.Symptoms of Alcoholic hepatitis can vary from mild to severe.The symptoms include nausea,malaise, low-grade fever, abdominal Pain, yellow discoloration of skin increased abdominal girth due to ascites, gastrointestinal bleeding due to variceal hemorrhage, lack of appetite, confusion, and lethargy.

History

Symptoms

References

  1. Dugum MF, McCullough AJ (2016). "Acute Alcoholic Hepatitis, the Clinical Aspects". Clin Liver Dis. 20 (3): 499–508. doi:10.1016/j.cld.2016.02.008. PMC 6130321. PMID 27373612.
  2. "Alcoholic Hepatitis - StatPearls - NCBI Bookshelf".

Template:WikiDoc Sources