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{{Acute pancreatitis}}
{{Acute pancreatitis}}
{{CMG}}; {{AE}} {{RT}}
{{CMG}}; {{AE}} {{RT}}


==Overview==
==Overview==
Although [[ultrasound imaging]] and [[CT scanning]] of the [[abdomen]] can be used to confirm the diagnosis of pancreatitis, neither is usually necessary as a primary diagnostic modality<ref name="pmid12792243">{{cite journal |author=Fleszler F, Friedenberg F, Krevsky B, Friedel D, Braitman L |title=Abdominal computed tomography prolongs length of stay and is frequently unnecessary in the evaluation of acute pancreatitis |journal=Am J Med Sci |volume=325 |issue=5 |pages=251-5 |year=2003 |id=PMID 12792243}}</ref>
. In addition, CT contrast may exacerbate pancreatitis,<ref name="pmid8678000">{{cite journal |author=McMenamin D, Gates L |title=A retrospective analysis of the effect of contrast-enhanced CT on the outcome of acute pancreatitis |journal=Am J Gastroenterol |volume=91|issue=7 |pages=1384-7 |year=1996 |id=PMID 8678000}}</ref> although this is disputed.<ref name="pmid10722029">{{cite journal|author=Hwang T, Chang K, Ho Y |title=Contrast-enhanced dynamic computed tomography does not aggravate the clinical severity of patients with severe acute pancreatitis: reevaluation of the effect of intravenous contrast medium on the severity of acute pancreatitis|journal=Arch Surg |volume=135 |issue=3 |pages=287-90 |year=2000 |id=PMID 10722029}}</ref><ref name="acutepancreatitis">{{cite journal
| last      = Forsmark
| first      = Chris E.
| last2      = Vege
| first2    = Santhi Swaroop
| last3      = Wilcox
| first3    = Mel
| date      = November 17,2016
| title      = Acute Pancreatitis
| url        = http://www.nejm.org/doi/full/10.1056/NEJMra1505202
| journal    = The New England Journal of Medicine
| volume    =
| issue      =
| pages      = 1972 - 1981
| doi        = 10.1056/NEJMra1505202
| pmc        =
| pmid      =
| access-date = November 25,2016
| name-list-format = vanc
}}</ref>


 
==CT==
 
==Computed tomography==
 
Regarding the need for [[computed tomography]], practice guidelines state:
Regarding the need for [[computed tomography]], practice guidelines state:
: 2006: "Many patients with acute pancreatitis do not require a [[CT scan]] at admission or at any time during the [[hospitalization]]. For example, a [[CT scan]] is usually not essential in patients with recurrent mild pancreatitis caused by alcohol. A reasonable indication for a [[CT scan]] at admission (but not necessarily a [[CT]] with IV contrast) is to distinguish acute pancreatitis from another serious intra-abdominal condition, such as a [[perforated ulcer]]." <ref name="pmid17032204">{{cite journal |author=Banks P, Freeman M |title=Practice guidelines in acute pancreatitis |journal=Am J Gastroenterol |volume=101 |issue=10 |pages=2379-400 |year=2006 |id=PMID 17032204 | doi=10.1111/j.1572-0241.2006.00856.x}}</ref><ref name="acutepancreatitis">{{cite journal
| last      = Forsmark
| first      = Chris E.
| last2      = Vege
| first2    = Santhi Swaroop
| last3      = Wilcox
| first3    = Mel
| date      = November 17,2016
| title      = Acute Pancreatitis
| url        = http://www.nejm.org/doi/full/10.1056/NEJMra1505202
| journal    = The New England Journal of Medicine
| volume    =
| issue      =
| pages      = 1972 - 1981
| doi        = 10.1056/NEJMra1505202
| pmc        =
| pmid      =
| access-date = November 25,2016
| name-list-format = vanc
}}</ref>


: 2006: "Many patients with acute pancreatitis do not require a CT scan at admission or at any time during the hospitalization. For example, a CT scan is usually not essential in patients with recurrent mild pancreatitis caused by alcohol. A reasonable indication for a CT scan at admission (but not necessarily a CT with IV contrast) is to distinguish acute pancreatitis from another serious intra-abdominal condition, such as a perforated ulcer." <ref name="pmid17032204">{{cite journal |author=Banks P, Freeman M |title=Practice guidelines in acute pancreatitis |journal=Am J Gastroenterol |volume=101 |issue=10 |pages=2379-400 |year=2006 |id=PMID 17032204 | doi=10.1111/j.1572-0241.2006.00856.x}}</ref>
: 2005: "Patients with persisting organ failure, signs of [[sepsis]], or deterioration in clinical status 6–10 days after admission will require [[CT]] (recommendation grade B)."<ref name="pmid15831893">{{cite journal |author=UK Working Party on Acute Pancreatitis |title=UK guidelines for the management of acute pancreatitis |journal=Gut |volume=54 Suppl 3 |issue= |pages=iii1-9 |year=2005 |id=PMID 15831893 | doi=10.1136/gut.2004.057026 | url=http://gut.bmj.com/cgi/content/full/54/suppl_3/iii1}}</ref>
 
: 2005: "Patients with persisting organ failure, signs of sepsis, or deterioration in clinical status 6–10 days after admission will require CT (recommendation grade B)."<ref name="pmid15831893">{{cite journal |author=UK Working Party on Acute Pancreatitis |title=UK guidelines for the management of acute pancreatitis |journal=Gut |volume=54 Suppl 3 |issue= |pages=iii1-9 |year=2005 |id=PMID 15831893 | doi=10.1136/gut.2004.057026 | url=http://gut.bmj.com/cgi/content/full/54/suppl_3/iii1}}</ref>
 
CT abdomen should not be performed before the 1st 48 hours of onset of symptoms as early CT (<48 h) may result in equivocal or normal findings.
 
CT Findings can be classified into the following categories for easy recall :
*Intrapancreatic - diffuse or segmental enlargement, edema, gas bubbles, pancreatic pseudocysts and phlegmons/abscesses (which present 4 to 6 wks after initial onset)
*Peripancreatic / extrapancreatic - irregular pancreatic outline, obliterated peripancreatic fat, retroperitoneal edema, fluid in the lessar sac, fluid in the left anterior pararenal space
*Locoregional - Gerota's fascia sign (thickening of inflamed Gerota's fascia, which becomes visible), pancreatic ascites, pleural effusion (seen on basal cuts of the pleural cavity), adynamic ileus,
 
==='''Patient #1: Gallstone pancreatitis'''===
 
[http://www.radswiki.net Images courtesy of RadsWiki]
 
<gallery perRow="3">
Image:Gallstone-pancreatitis-001.jpg
Image:Gallstone-pancreatitis-002.jpg
Image:Gallstone-pancreatitis-003.jpg
Image:Gallstone-pancreatitis-004.jpg
Image:Gallstone-pancreatitis-005.jpg
Image:Gallstone-pancreatitis-006.jpg
</gallery>


==='''Patient #2: Necrotizing pancreatitis'''===
CT abdomen should not be performed before the 1st 48 hours of onset of symptoms as early [[CT]] (<48 h) may result in equivocal or normal findings.


[http://www.radswiki.net Images courtesy of RadsWiki]
CT findings can be classified into the following categories for easy recall :
 
*Intrapancreatic - diffuse or segmental enlargement, [[edema]], gas bubbles, [[Pancreatic pseudocyst|pancreatic pseudocysts]] and phlegmons/[[abscesses]] (which present 4 to 6 weeks after initial onset)
<gallery>
*Peripancreatic / extrapancreatic - irregular pancreatic outline, obliterated peripancreatic fat, [[retroperitoneal]] [[edema]], fluid in the lesser sac, fluid in the left [[anterior]] pararenal space
Image:Necrotizing pancreatitis 001.jpg
*Locoregional - [[Gerota's fascia]] sign (thickening of inflamed [[Gerota's fascia]], which becomes visible), pancreatic [[ascites]], [[pleural effusion]] (seen on basal cuts of the [[pleural cavity]]), [[adynamic ileus]],
Image:Necrotizing pancreatitis 002.jpg
===Balthazar Scoring===
Image:Necrotizing pancreatitis 003.jpg
Balthazar Scoring for the grading of acute pancreatitis:
</gallery>
* The [[Computed tomography|CT]] severity score is the sum of the CT Grade and Necrosis Grade Scores.
 
====Balthazar scoring====
Balthazar Scoring for the Grading of Acute Pancreatitis
 
The CT Severity Score is the sum of the CT Grade and Necrosis Grade Scores.
 
CT Grade Score


===== CT Grade Score: =====
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Necrosis score
===== Necrosis score: =====
 
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[[Image:Acute-pancreatitis-8.jpg|500 px|thumb|center|Case courtesy of Dr Rahmoun Fateh, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/18850">rID: 18850</a>]]
[[Image:Acute-pancreatitis.jpg|500 px|thumb|center|Case courtesy of <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/11163">rID: 11163</a>]]
[[Image:Acute-pancreatitis-14 (1).jpg|500 px|thumb|center|Case courtesy of David Puyó, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/22434">rID: 22434</a>]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Gastroenterology]]
[[Category:Surgery]]
[[Category:Emergency medicine]]
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{{WH}}
{{WH}}
{{WS}}

Latest revision as of 18:59, 21 December 2017

Acute pancreatitis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Although ultrasound imaging and CT scanning of the abdomen can be used to confirm the diagnosis of pancreatitis, neither is usually necessary as a primary diagnostic modality[1] . In addition, CT contrast may exacerbate pancreatitis,[2] although this is disputed.[3][4]

CT

Regarding the need for computed tomography, practice guidelines state:

2006: "Many patients with acute pancreatitis do not require a CT scan at admission or at any time during the hospitalization. For example, a CT scan is usually not essential in patients with recurrent mild pancreatitis caused by alcohol. A reasonable indication for a CT scan at admission (but not necessarily a CT with IV contrast) is to distinguish acute pancreatitis from another serious intra-abdominal condition, such as a perforated ulcer." [5][4]
2005: "Patients with persisting organ failure, signs of sepsis, or deterioration in clinical status 6–10 days after admission will require CT (recommendation grade B)."[6]

CT abdomen should not be performed before the 1st 48 hours of onset of symptoms as early CT (<48 h) may result in equivocal or normal findings.

CT findings can be classified into the following categories for easy recall :

Balthazar Scoring

Balthazar Scoring for the grading of acute pancreatitis:

  • The CT severity score is the sum of the CT Grade and Necrosis Grade Scores.
CT Grade Score:
CT Grade Appearance on CT CT Grade Points
Grade A Normal CT 0 points
Grade B Focal or diffuse enlargement of the pancreas 1 point
Grade C Pancreatic gland abnormalities and peripancreatic inflammation 2 points
Grade D Fluid collection in a single location 3 points
Grade E Two or more fluid collections and / or gas bubbles in or adjacent to pancreas 4 points
Necrosis score:
Necrosis Percentage Points
No necrosis 0 points
0 to 30% necrosis 2 points
30 to 50% necrosis 4 points
Over 50% necrosis 6 points
Case courtesy of Dr Rahmoun Fateh, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/18850">rID: 18850</a>
Case courtesy of <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/11163">rID: 11163</a>
Case courtesy of David Puyó, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/22434">rID: 22434</a>

References

  1. Fleszler F, Friedenberg F, Krevsky B, Friedel D, Braitman L (2003). "Abdominal computed tomography prolongs length of stay and is frequently unnecessary in the evaluation of acute pancreatitis". Am J Med Sci. 325 (5): 251–5. PMID 12792243.
  2. McMenamin D, Gates L (1996). "A retrospective analysis of the effect of contrast-enhanced CT on the outcome of acute pancreatitis". Am J Gastroenterol. 91 (7): 1384–7. PMID 8678000.
  3. Hwang T, Chang K, Ho Y (2000). "Contrast-enhanced dynamic computed tomography does not aggravate the clinical severity of patients with severe acute pancreatitis: reevaluation of the effect of intravenous contrast medium on the severity of acute pancreatitis". Arch Surg. 135 (3): 287–90. PMID 10722029.
  4. 4.0 4.1 Forsmark CE, Vege SS, Wilcox M (November 17,2016). "Acute Pancreatitis". The New England Journal of Medicine: 1972–1981. doi:10.1056/NEJMra1505202. Retrieved November 25,2016. Check date values in: |access-date=, |date= (help)
  5. Banks P, Freeman M (2006). "Practice guidelines in acute pancreatitis". Am J Gastroenterol. 101 (10): 2379–400. doi:10.1111/j.1572-0241.2006.00856.x. PMID 17032204.
  6. UK Working Party on Acute Pancreatitis (2005). "UK guidelines for the management of acute pancreatitis". Gut. 54 Suppl 3: iii1–9. doi:10.1136/gut.2004.057026. PMID 15831893.

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