Butalbital

Butalbital

File:Butalbital.png
Clinical data
Pregnancy category	US: D (Evidence of risk)
Routes of administration	oral
Legal status
Legal status	US: Schedule III
Pharmacokinetic data
Bioavailability	well absorbed
Metabolism	hepatic
Elimination half-life	35 hours
Excretion	?
Identifiers
IUPAC name 5-(2-methylpropyl)-5-(2-propenyl)- 2,4,6(1H,3H,5H)-pyrimidinetrione
CAS Number	77-26-9
PubChem CID	2481
DrugBank	APRD00266
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C11H16N2O3
Molar mass	224.256

Butalbital, 5-allyl-5-isobutylbarbituric acid, is a barbiturate with an intermediate duration of action. It has the same chemical formula as talbutal but a different structure. Butalbital is often combined with other medications, such as acetaminophen or aspirin, and is commonly prescribed for the treatment of pain and headache. The various formulations combined with codeine are FDA approved for the treatment of tension headaches.

Combinations include:

• butalbital and acetaminophen (trade names: Axocet, Bucet, Bupap, Cephadyn, Dolgic, Phrenilin, Phrenilin Forte, Sedapap)
• butalbital, acetaminophen, and caffeine (trade names: Fioricet, Esgic, Esgic-Plus)
• butalbital and aspirin (trade name: Axotal)
• butalbital, aspirin, and caffeine (trade names Fiorinal, Fiormor, Fiortal, Fortabs, Laniroif)
• butalbital, acetaminophen, caffeine, and codeine phosphate (Fioricet #3 with Codeine)
• butalbital, aspirin, caffeine, and codeine phosphate (trade name: Fiorinal #3 with Codeine)

File:Fioricet.jpg

Fioricet (50/40/325)

Side effects

Side effects for any drug are difficult to predict, but commonly reported side effects for butalbital include:

• Dizziness
• Drowsiness
• Intoxicated feeling
• Light-headedness
• Nausea
• Sedation
• Addiction
• Severe impairment of judgement

There are other potential side effects, this list should not be considered all-inclusive.

Pill Images

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Dangers and Risks

Butalbital is a physically and psychologically addictive barbiturate. Butalbital should not be mixed with alcohol due to increased risk of intoxication.

There are other potential risks; this list should not be considered all-inclusive.

External links

"Butalbital". On-line Medical Dictionary.

"Butalbital and Acetaminophen (Systemic)". MedicinePlus Drug Information.

"Controlled Substances in Schedule III". Drug Enforcement Administration. 2007. Retrieved 2007-01-13.

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