Burkitt's lymphoma differential diagnosis

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Assistant Editor-in-Chief: Soumya Sachdeva

It ,sometimes , becomes very difficult for the pathologist to differentiate between burkitt's lymphoma and diffuse large B cell lymphoma.They can be differentiated only by the fact that there is a very high proliferative fraction seen in patients with burkitt's lymphoma(i.e.,essentially 100% of tumor cells are in cycle) caused by c-myc deregulation.  

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