Mitral stenosis general approach to mitral stenosis

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Mitral Stenosis Microchapters

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Overview

Pathophysiology

Causes

Differentiating Mitral Stenosis from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

Diagnosis

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History and Symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Mitral stenosis is a valvular disease characterized by a narrowing in the heart valve between the two left chambers of the heart (left atrium and left ventricle).

Pathophysiology

  • Commisural fusion is the hallmark anatomic finding in mitral stenosis.
  • The narrowing in the mitral valve causes build up of pressures in the left atrium, and eventually in the pulmonary bed.
  • The build up of pressures in the pulmonary bed leads to pulmonary hypertension which results in right heart failure.
  • The left ventricle is unaffected in pure mitral stenosis.

Causes

The cause of mitral stenosis is almost always rheumatic heart disease.

Differentiating Mitral stenosis from other Diseases

Mitral stenosis should be differentiated from:

Natural History and Complications

Natural History

Mitral stenosis is intermittently progressive and has a prolonged clinical course before becoming severe.

Complications

Complications occur in the late stages of mitral stenosis. They include:

Diagnosis

Symptoms

Symptoms of mitral stenosis occur late in the course of the disease as the disease progresses slowly over decades. Common symptoms include:

Physical Examination

  • A high pitched additional sound called opening snap may be heard after the A2 component of S2 and it signifies the forceful opening of the mitral valve.

References

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