Squamous cell carcinoma future and investigational treatment strategies
Squamous cell carcinoma of the skin Microchapters |
Differentiating Squamous cell carcinoma of the skin from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2],Raviteja Guddeti, M.B.B.S. [3]
Future and Investigational treatment strategies
In 2007, the Australian biopharmaceutical company, Clinuvels Pharmaceuticals Limited began clinical trials with a melanocyte-stimulating hormone called melanotan (known by the International Nonproprietary Name afamelanotide, formerly CUV1647)[1] to provide photoprotection for organ transplant patients against squamous cell carcinoma of the skin and actinic keratosis.[2][3]
Cetuximab is a monoclonal antibody which targets the epidermal growth factor receptor (EGFR), and has antitumor activity in patients with advanced squamous cell carcinoma of the skin as suggested by case reports.
The use of natural agents in the treatment of cancer is gaining popularity. For oral squamous cell carcinoma, use of curcumin microemulsions is under consideration. New modalities, such as the use of ultrasound mediated delivery of these microemulsions are also being investigated. [4]
References
- ↑ "World Health Organisation assigns CUV1647 generic name" (PDF). Clinuvel. 2008. Retrieved 2008-06-17.
- ↑ Clinuvel » Investors » FAQs
- ↑ PharmaAsia - Clinuvel’s Drug Begins Global Phase II Skin Cancer Trials
- ↑ Lenaz G, Fato R, Baracca A, Solaini G, Parenti Castelli G, Rabbi A (1988). "Dynamics of biological membranes". Ann. Ist. Super. Sanita. 24 (1): 9–21. PMID 3289448.
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