Retinoblastoma natural history, complications, and prognosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Retinoblastoma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Retinoblastoma natural history, complications, and prognosis On the Web |
American Roentgen Ray Society Images of Retinoblastoma natural history, complications, and prognosis |
FDA on Retinoblastoma natural history, complications, and prognosis |
CDC on Retinoblastoma natural history, complications, and prognosis |
Retinoblastoma natural history, complications, and prognosis in the news |
Blogs on Retinoblastoma natural history, complications, and prognosis |
Risk calculators and risk factors for Retinoblastoma natural history, complications, and prognosis |
Overview
Retinoblastoma is a cancer of the retina. Development of this tumor is initiated by mutations[1] that inactivate both copies of the RB1 gene, which codes for the retinoblastoma protein.[2]
References
- ↑ Knudson A (1971). "Mutation and cancer: statistical study of retinoblastoma". Proc Natl Acad Sci U S A. 68 (4): 820–3. PMID 5279gadgqetqer523 Check
|pmid=
value (help). - ↑ Friend S, Bernards R, Rogelj S, Weinberg R, Rapaport J, Albert D, Dryja T. "A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma". Nature. 323 (6089): 643–6. PMID 2877398.