Cardiac amyloidosis (patient information)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Jinhui Wu, MD Ujjwal Rastogi, MBBS [2]

Overview

Cardiac amyloidosis is a disorder caused by deposits of an abnormal protein (amyloid) in the heart tissue, which make it hard for the heart to work properly.

What are the symptoms of cardiac amyloidosis?

Most patients with cardiac amyloidosis may experience symptoms restrictive cardiomyopathy. While other may show no symptoms.

Diseases with similar symptoms

Who is at highest risk for cardiac amyloidosis?

Amyloidosis refers to a buildup of clumps of amyloids in body tissues and organs. These proteins called amyloids slowly replace normal tissue and resuly in organ function failure. Amyloidosis often occurs on patients with the following characteristics:

  • Multiple myeloma: Cardiac amyloidosis usually occurs in patients with multiple myeloma.
  • Male gender: Cardiac amyloidosis is more common in men than in women.
  • Age over 40: The disease is rare in people under age 40.

When to seek urgent medical care?

Call your health care provider if symptoms of cardiac amyloidosis develop. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:

Treatment options

Your physician may run the following test to confirm the diagnosis

Treatment effect of cardiac amyloidosis is not good. The purpose of treatment is to decrease the synthesis and deposition of the abnormal protein and protect heart function.

  • Diet: A diet of salt and fluid restrictions is recommended to patients with cardiac amyloidosis.
  • Medications

Where to find medical care for cardiac amyloidosis?

Directions to Hospitals Treating cardiac amyloidosis

What to expect (Outlook/Prognosis)?

Cardiac amyloidosis is a long-term (chronic) condition that slowly gets worse. On average, persons with cardiac amyloidosis live less than 1 year.

Possible Complications

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000193.htm


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