Osteoarthritis pathophysiology

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Osteoarthritis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

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Pathophysiology

Osteoarthritis (OA) is a well-known degenerative joint disease influencing millions of peopleworldwide. Osteoarthritis count as a complex disease caused by changes in the tissue homeostasis of articular cartilages and subchondral bones. The cell/extra-cellular matrix (ECM) and their interactions play an important role in the pathophysiology of articular cartilage and then the occurrence of Osteoarthritis.

References