Hypopharyngeal cancer causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Causes
Factors that contribute to the development of hypopharyngeal cancer include:[1] Smoking: alterations may change a normal DNA sequence to an oncogene, a gene that causes cancer after exposure to a carcinogen Squamous cells, a type of cell that lines hollow organs like the throat, mouth, lungs, and outer layer of skin, are particularly vulnerable when exposed to cigarette smoke
Chewing tobacco The chewing tobacco is placed into the mouth, leaving it exposed toenzymes, like amylase, which partly digests the carcinogenic material. Saliva is swallowed, along with the cancer-promoting material, which passes through the hypopharynx on its way to the esophagus. Heavy alcohol use Heavy alcohol use is linked to Hypopharyngeal Cancer as well. Alcohol damages the lining of the hypopharynx, increasing the amount of chemicals that are allowed to seep into the underlying membranes. Heavy alcohol use is also associated with nutritional deficiencies Poor diet Plummer-Vinson syndrome A disease called Plummer-Vinson syndrome, a genetic disorder that causes a long-term iron deficiency, may also lead to Hypopharyngeal Cancer. Other factors like a deficiency in certain vitamins also appear to contribute to this type of cancer.
References
- ↑ Causes of hypopharyngeal cancer. Wikipedia. https://en.wikipedia.org/wiki/Hypopharyngeal_cancer#cite_note-National_Cancer_Institute._General_Information_About_Hypopharyngeal_Cancer-1