Chorioamnionitis primary prevention
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Overview
Primary preventative measures to avoid the development of chorioamnionitis include induction of labor and administration of prophylactic antimicrobial therapy.
Primary Prevention
Induction of Labor
- Induction of labor and delivery for preterm premature rupture of membranes (PPROM) after 34 weeks’ gestation is recommended.
Prophylactic Therapy
- 1. Prophylactic Antimicrobial Regimen [1]
- Preferred regimen: (Erythromycin OR Azithromycin) AND Ampicillin for 7–10 days IV for 2 days followed by oral routes.
- 2. Antipyretic Therapy
References
- ↑ Fishman SG, Gelber SE (2012). "Evidence for the clinical management of chorioamnionitis". Semin Fetal Neonatal Med. 17 (1): 46–50. doi:10.1016/j.siny.2011.09.002. PMID 21962477.