Chorioamnionitis future or investigational therapies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]

Overview

Future or investigational therapies for clinical chorioamnionitis include administration of vaginal antiseptic solutions and antenatal N-acetylcysteine (NAC).

Future or Investigational Therapies

Future or investigational therapies for clinical chorioamnionitis include:[1]

  • Use of antiseptic solutions for vaginal cleansing before the procedure of cesarean section
    • It might decrease the risk of poor infectious outcomes caused by clinical chorioamnionitis during the postoperative period.
  • Administration of N‑acetylcysteine (NAC) in patients with clinical chorioamnionitis during the antenatal period
    • It might decrease the morbidity and mortality in neonates exposed to clinical chorioamnionitis.

References

  1. Conde-Agudelo A, Romero R, Jung EJ, Garcia Sánchez ÁJ (December 2020). "Management of clinical chorioamnionitis: an evidence-based approach". Am J Obstet Gynecol. 223 (6): 848–869. doi:10.1016/j.ajog.2020.09.044. PMID 33007269 Check |pmid= value (help).

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