Cryoglobulinemia medical therapy

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Cryoglobulinemia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Feham Tariq, MD [2]

Overview

Medical Therapy

The medical treatment of cryoglobulinemia depends on the underlying etiology, nature and progression of the disease. The main indication for therapy is to halt the progressive end organ damage affecting the kidneys, skin, gastrointestinal system, central nervous system and the extremities.

Medical Therapy

The main pharmacotherapy for each type of cryoglobulinemia is discussed below:

Assymptomatic cryoglobulinemia

  • This type of cryoglobulinemia requires no medical treatment.

Secondary cryoglobulinemia

This category includes type 1 and mixed cyroglobulinemia. The goal of treatment of this type is as follows:

    • Conservative management
    • Immunosuppressive agents
    • Plasmapheresis

Immunosuppressive agents

  • The main aim of immunosuppressive therapy in cryoglobulinemia is its employment for the patients having rapidly progressive, organ-threatening or like-threatening course of the disease regardless og the underlying cause.

Cryoglobulinemia associated with Hepatitis C virus

References


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