Heartburn causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]
Overview
Heartburn is commonly caused by gastroesophageal reflux disease (GERD) or adverse reactions to various food and drugs, causing esophagitis. Life threatening causes of heartburn are far less common and include acute coronary syndromes and esophageal cancer.
Overview
Heartburn is commonly caused by sources of acid reflux, including adverse reactions with various food and drugs.
Esophageal and gastrointestinal cancer are potentially life threatening causes of heartburn and require prompt diagnosis and management.
Causes
Life Threatening Causes
These causes present with chest pain that may present similarly to heartburn and also other clinical features that occur with heartburn:
Common Causes
- Gastroesophageal reflux disease (GERD)
- Esophagitis
- Motility disorders (e.g., gastroparesis)
- Peptic ulcer disorder
- Lifestyle:
- Medications:
- Alpha-adrenergic antagonists
- Anticholinergic agents
- [[Aspirin and other nonsteroidal anti-inflammatory drugs
- Beta2 -adrenergic drugs
- Barbiturates
- Benzodiazepines
- Bisphosphonates
- Calcium channel blockers
- Chemotherapy
- Dopamine
- Estrogen
- Iron
- Narcotic analgesics
- Nitrates
- Potassium
- Progesterone
- Prostaglandins
- Quinidine
- Tetracycline
- Theophylline
- Tricyclic antidepressants
- Zidovudine
- Dietary:
- Alcohol
- Caffeinated beverages
- Carbonated beverages
- Chocolate
- Citrus fruit or juices
- Fatty foods
- Garlic or onions
- Mint (peppermint, spearmint)
- Salt and salt substitutes
- Spicy foods
- Tomatoes/tomato juice
- Other:
- Genetics
- Pregnancy[1]
Less Common Causes
References
- ↑ "www.worldgastroenterology.org" (PDF).