Sandbox anthrax01: Difference between revisions

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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Preferred Regimen
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Ciprofloxacin]]  400 mg IV q8h'''''<BR> OR <BR> ▸ '''''[[Levofloxacin]]  750 mg IV q24h'''''<BR> OR <BR> ▸ '''''[[Moxifloxacin]]  400 mg IV q24h'''''
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Meropenem]]  2 g IV q8h'''''<BR> OR <BR> ▸ '''''[[imipenem]]  1 g IV q6h'''''<BR> OR <BR> ▸ '''''[[Doripenem]]  500 mg IV q8h'''''
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Linezolid]]  600 mg IV q12h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]]  900 mg IV q8h'''''<BR> OR <BR> ▸ '''''[[Rifampin]]  600 mg IV q12h'''''<BR> OR <BR> ▸ '''''[[Chloramphenicol]] 1 g IV q6–8h'''''
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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Alternative Regimen (for Penicillin-Susceptible Strains)
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Ciprofloxacin]]  400 mg IV q8h'''''<BR> OR <BR> ▸ '''''[[Levofloxacin]]  750 mg IV q24h'''''<BR> OR <BR> ▸ '''''[[Moxifloxacin]]  400 mg IV q24h'''''
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Penicillin G]]  4 MU IV q4h'''''<BR> OR <BR> ▸ '''''[[Ampicillin]]  3 g IV q6h'''''
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Linezolid]]  600 mg IV q12h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]]  900 mg IV q8h'''''<BR> OR <BR> ▸ '''''[[Rifampin]]  600 mg IV q12h'''''<BR> OR <BR> ▸ '''''[[Chloramphenicol]] 1 g IV q6–8h'''''
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Revision as of 15:39, 17 July 2014


▸ Click on the following categories to expand treatment regimens.

Cutaneous Anthrax Without Systemic Involvement

  ▸  Adult Patients

  ▸  Pediatric Patients

  ▸  Pregnant Patients

Systemic Anthrax with Possible/Confirmed Meningitis

  ▸  Adult Patients

  ▸  Pediatric Patients

  ▸  Pregnant Patients

Systemic Anthrax Without Meningitis

  ▸  Adult Patients

  ▸  Pediatric Patients

  ▸  Pregnant Patients


Cutaneous Anthrax, Adult Patients
Preferred Regimen
Ciprofloxacin 500 mg PO q12h
OR
Levofloxacin 750 mg PO q24h
OR
Moxifloxacin 400 mg PO q24h
OR
Doxycycline 100 mg PO q12h
Alternative Regimen (for Penicillin-Susceptible Strains)
Clindamycin 600 mg PO q8h
OR
Penicillin VK 500 mg PO q6h
OR
Amoxicillin 1 g PO q8h
Cutaneous Anthrax, Pediatric Patients
Preferred Regimen
Ciprofloxacin 30 mg/kg/day PO q12h, max: 500 mg/dose
OR
Levofloxacin 16 mg/kg/day PO q12h, max: 250 mg/dose (<50 kg)
OR
Levofloxacin 500 mg PO q24h (≥50 kg)
OR
Doxycycline 4.4 mg/kg/day PO q12h, max: 100 mg/dose (<45 kg)
OR
Doxycycline 100 mg/dose PO q12h (≥45 kg)
Alternative Regimen (for Penicillin-Susceptible Strains)
Clindamycin 30 mg/kg/day PO q8h, max: 600 mg/dose
OR
Penicillin VK 50–75 mg/kg/day PO q6–8h
OR
Amoxicillin 75 mg/kg/day PO q8h, max: 1 g/dose
Cutaneous Anthrax, Pregnant Patients
Preferred Regimen
Ciprofloxacin 500 mg PO q12h


Systemic Anthrax with Meningitis, Adult Patients
Preferred Regimen
Ciprofloxacin 400 mg IV q8h
OR
Levofloxacin 750 mg IV q24h
OR
Moxifloxacin 400 mg IV q24h
PLUS
Meropenem 2 g IV q8h
OR
imipenem 1 g IV q6h
OR
Doripenem 500 mg IV q8h
PLUS
Linezolid 600 mg IV q12h
OR
Clindamycin 900 mg IV q8h
OR
Rifampin 600 mg IV q12h
OR
Chloramphenicol 1 g IV q6–8h
Alternative Regimen (for Penicillin-Susceptible Strains)
Ciprofloxacin 400 mg IV q8h
OR
Levofloxacin 750 mg IV q24h
OR
Moxifloxacin 400 mg IV q24h
PLUS
Penicillin G 4 MU IV q4h
OR
Ampicillin 3 g IV q6h
PLUS
Linezolid 600 mg IV q12h
OR
Clindamycin 900 mg IV q8h
OR
Rifampin 600 mg IV q12h
OR
Chloramphenicol 1 g IV q6–8h









References