Wolff-Parkinson-White syndrome epidemiology and demographics: Difference between revisions

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* Prevalence increases in first degree relatives in which it can get as high as 5-6 per 1000 people.<ref name="pmid22579340">{{cite journal| author=Pediatric and Congenital Electrophysiology Society (PACES). Heart Rhythm Society (HRS). American College of Cardiology Foundation (ACCF). American Heart Association (AHA). American Academy of Pediatrics (AAP). Canadian Heart Rhythm Society (CHRS) et al.| title=PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology Foundation (ACCF), the American Heart Association (AHA), the American Academy of Pediatrics (AAP), and the Canadian Heart Rhythm Society (CHRS). | journal=Heart Rhythm | year= 2012 | volume= 9 | issue= 6 | pages= 1006-24 | pmid=22579340 | doi=10.1016/j.hrthm.2012.03.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22579340  }} </ref>  
* Prevalence increases in first degree relatives in which it can get as high as 5-6 per 1000 people.<ref name="pmid22579340">{{cite journal| author=Pediatric and Congenital Electrophysiology Society (PACES). Heart Rhythm Society (HRS). American College of Cardiology Foundation (ACCF). American Heart Association (AHA). American Academy of Pediatrics (AAP). Canadian Heart Rhythm Society (CHRS) et al.| title=PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology Foundation (ACCF), the American Heart Association (AHA), the American Academy of Pediatrics (AAP), and the Canadian Heart Rhythm Society (CHRS). | journal=Heart Rhythm | year= 2012 | volume= 9 | issue= 6 | pages= 1006-24 | pmid=22579340 | doi=10.1016/j.hrthm.2012.03.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22579340  }} </ref>  
* The incidence of tachyarrythmias is not well established in patients who present WPW pattern. It has been reported that the incidence of tachyarritmias is approximatley 1% per year in patients with WPW pattern.<ref name="Fitzsimmons-2001">{{Cite journal  | last1 = Fitzsimmons | first1 = PJ. | last2 = McWhirter | first2 = PD. | last3 = Peterson | first3 = DW. | last4 = Kruyer | first4 = WB. | title = The natural history of Wolff-Parkinson-White syndrome in 228 military aviators: a long-term follow-up of 22 years. | journal = Am Heart J | volume = 142 | issue = 3 | pages = 530-6 | month = Sep | year = 2001 | doi = 10.1067/mhj.2001.117779 | PMID = 11526369 }}</ref>
* The incidence of tachyarrythmias is not well established in patients who present WPW pattern. It has been reported that the incidence of tachyarritmias is approximatley 1% per year in patients with WPW pattern.<ref name="Fitzsimmons-2001">{{Cite journal  | last1 = Fitzsimmons | first1 = PJ. | last2 = McWhirter | first2 = PD. | last3 = Peterson | first3 = DW. | last4 = Kruyer | first4 = WB. | title = The natural history of Wolff-Parkinson-White syndrome in 228 military aviators: a long-term follow-up of 22 years. | journal = Am Heart J | volume = 142 | issue = 3 | pages = 530-6 | month = Sep | year = 2001 | doi = 10.1067/mhj.2001.117779 | PMID = 11526369 }}</ref>
* The incidence of sudden cardiac death in patients with Wolff-Parkinson-White pattern is not high. A metaanalysis involving twenty studies estimated that the sudden cardiac death in patients with  asymptomatic preexcitations was around 1.3 per 1000 patient-years.<ref>{{Cite journal  | last1 = Obeyesekere | first1 = MN. | last2 = Leong-Sit | first2 = P. | last3 = Massel | first3 = D. | last4 = Manlucu | first4 = J. | last5 = Modi | first5 = S. | last6 = Krahn | first6 = AD. | last7 = Skanes | first7 = AC. | last8 = Yee | first8 = R. | last9 = Gula | first9 = LJ. | title = Risk of arrhythmia and sudden death in patients with asymptomatic preexcitation: a meta-analysis. | journal = Circulation | volume = 125 | issue = 19 | pages = 2308-15 | month = May | year = 2012 | doi = 10.1161/CIRCULATIONAHA.111.055350 | PMID = 22532593 }}</ref>  Neveertheleess, it has been estimated to be 4.5 per 1000 patients-years in one recent series.<ref name="pmid22579340">{{cite journal| author=Pediatric and Congenital Electrophysiology Society (PACES). Heart Rhythm Society (HRS). American College of Cardiology Foundation (ACCF). American Heart Association (AHA). American Academy of Pediatrics (AAP). Canadian Heart Rhythm Society (CHRS) et al.| title=PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology Foundation (ACCF), the American Heart Association (AHA), the American Academy of Pediatrics (AAP), and the Canadian Heart Rhythm Society (CHRS). | journal=Heart Rhythm | year= 2012 | volume= 9 | issue= 6 | pages= 1006-24 | pmid=22579340 | doi=10.1016/j.hrthm.2012.03.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22579340  }} </ref>
* The incidence of sudden cardiac death in patients with Wolff-Parkinson-White pattern is not high. A metaanalysis involving twenty studies estimated that the sudden cardiac death in patients with  asymptomatic preexcitations was around 1.3 per 1000 patient-years.<ref>{{Cite journal  | last1 = Obeyesekere | first1 = MN. | last2 = Leong-Sit | first2 = P. | last3 = Massel | first3 = D. | last4 = Manlucu | first4 = J. | last5 = Modi | first5 = S. | last6 = Krahn | first6 = AD. | last7 = Skanes | first7 = AC. | last8 = Yee | first8 = R. | last9 = Gula | first9 = LJ. | title = Risk of arrhythmia and sudden death in patients with asymptomatic preexcitation: a meta-analysis. | journal = Circulation | volume = 125 | issue = 19 | pages = 2308-15 | month = May | year = 2012 | doi = 10.1161/CIRCULATIONAHA.111.055350 | PMID = 22532593 }}</ref>  Neveertheleess, it has been estimated as high as 4.5 per 1000 patients-years in one recent series.<ref name="pmid22579340">{{cite journal| author=Pediatric and Congenital Electrophysiology Society (PACES). Heart Rhythm Society (HRS). American College of Cardiology Foundation (ACCF). American Heart Association (AHA). American Academy of Pediatrics (AAP). Canadian Heart Rhythm Society (CHRS) et al.| title=PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology Foundation (ACCF), the American Heart Association (AHA), the American Academy of Pediatrics (AAP), and the Canadian Heart Rhythm Society (CHRS). | journal=Heart Rhythm | year= 2012 | volume= 9 | issue= 6 | pages= 1006-24 | pmid=22579340 | doi=10.1016/j.hrthm.2012.03.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22579340  }} </ref>
* Incidence of WPW is higher in men than in women in a ratio of approximately 2:1.  Also, [[atrial fibrillation]] and [[ventricular fibrillation]] are more common in men than in women with WPW.<ref>{{Cite web  | last =  | first =  | title = http://www.cardiology.sk/casopis/606/pdf/04.pdf | url = http://www.cardiology.sk/casopis/606/pdf/04.pdf | publisher =  | date =  | accessdate = 11 April 2014 }}</ref>
* Incidence of WPW is higher in men than in women in a ratio of approximately 2:1.  Also, [[atrial fibrillation]] and [[ventricular fibrillation]] are more common in men than in women with WPW.<ref>{{Cite web  | last =  | first =  | title = http://www.cardiology.sk/casopis/606/pdf/04.pdf | url = http://www.cardiology.sk/casopis/606/pdf/04.pdf | publisher =  | date =  | accessdate = 11 April 2014 }}</ref>
* Incidence of Orthodromic AVRT is more common in women than in men.<ref>{{Cite web  | last =  | first =  | title = http://www.cardiology.sk/casopis/606/pdf/04.pdf | url = http://www.cardiology.sk/casopis/606/pdf/04.pdf | publisher =  | date =  | accessdate = 11 April 2014 }}</ref>
* Incidence of Orthodromic AVRT is more common in women than in men.<ref>{{Cite web  | last =  | first =  | title = http://www.cardiology.sk/casopis/606/pdf/04.pdf | url = http://www.cardiology.sk/casopis/606/pdf/04.pdf | publisher =  | date =  | accessdate = 11 April 2014 }}</ref>

Revision as of 18:19, 11 April 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Epidemiology and Demographics

  • Estimated prevalence of WPW syndrome is 1 - 3 per 1000 people in the entire world.[1]
  • Prevalence increases in first degree relatives in which it can get as high as 5-6 per 1000 people.[1]
  • The incidence of tachyarrythmias is not well established in patients who present WPW pattern. It has been reported that the incidence of tachyarritmias is approximatley 1% per year in patients with WPW pattern.[2]
  • The incidence of sudden cardiac death in patients with Wolff-Parkinson-White pattern is not high. A metaanalysis involving twenty studies estimated that the sudden cardiac death in patients with asymptomatic preexcitations was around 1.3 per 1000 patient-years.[3] Neveertheleess, it has been estimated as high as 4.5 per 1000 patients-years in one recent series.[1]
  • Incidence of WPW is higher in men than in women in a ratio of approximately 2:1. Also, atrial fibrillation and ventricular fibrillation are more common in men than in women with WPW.[4]
  • Incidence of Orthodromic AVRT is more common in women than in men.[5]
  • The presentation of symptoms in aptients without heart structural abnormalities has been found to be age dependant.[1]
  • The frequency of Supraventricular tachycardias (SVT) usually decrease during the first year in more than 90% of the patients.[1]
  • In 30% of the patients, tachycardias recur during childhood at a mean age of 7 to 8 years of age.[1]
  • When patients with WPW present persistent symptomatic tachycardias over 5 years of age, they usually continue presenting SVT episodes for more than a decade later in 75% of the cases.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Pediatric and Congenital Electrophysiology Society (PACES). Heart Rhythm Society (HRS). American College of Cardiology Foundation (ACCF). American Heart Association (AHA). American Academy of Pediatrics (AAP). Canadian Heart Rhythm Society (CHRS); et al. (2012). "PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology Foundation (ACCF), the American Heart Association (AHA), the American Academy of Pediatrics (AAP), and the Canadian Heart Rhythm Society (CHRS)". Heart Rhythm. 9 (6): 1006–24. doi:10.1016/j.hrthm.2012.03.050. PMID 22579340.
  2. Fitzsimmons, PJ.; McWhirter, PD.; Peterson, DW.; Kruyer, WB. (2001). "The natural history of Wolff-Parkinson-White syndrome in 228 military aviators: a long-term follow-up of 22 years". Am Heart J. 142 (3): 530–6. doi:10.1067/mhj.2001.117779. PMID 11526369. Unknown parameter |month= ignored (help)
  3. Obeyesekere, MN.; Leong-Sit, P.; Massel, D.; Manlucu, J.; Modi, S.; Krahn, AD.; Skanes, AC.; Yee, R.; Gula, LJ. (2012). "Risk of arrhythmia and sudden death in patients with asymptomatic preexcitation: a meta-analysis". Circulation. 125 (19): 2308–15. doi:10.1161/CIRCULATIONAHA.111.055350. PMID 22532593. Unknown parameter |month= ignored (help)
  4. "http://www.cardiology.sk/casopis/606/pdf/04.pdf" (PDF). Retrieved 11 April 2014. External link in |title= (help)
  5. "http://www.cardiology.sk/casopis/606/pdf/04.pdf" (PDF). Retrieved 11 April 2014. External link in |title= (help)

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