Doxycycline calcium indications and usage: Difference between revisions
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Doxycycline is indicated for the treatment of the following infections: | Doxycycline is indicated for the treatment of the following infections: | ||
*Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick | *Rocky Mountain spotted fever, [[typhus fever]] and the typhus group, Q fever, rickettsialpox, and [[tick fever]]s caused by Rickettsiae. | ||
*Respiratory tract infections caused by Mycoplasma pneumoniae. | *Respiratory tract infections caused by [[Mycoplasma pneumoniae]]. | ||
*Lymphogranuloma venereum caused by Chlamydia trachomatis. | *[[Lymphogranuloma venereum]] caused by [[Chlamydia trachomatis]]. | ||
*Psittacosis (ornithosis) caused by Chlamydophila psittaci. | *[[Psittacosis]] (ornithosis) caused by [[Chlamydophila psittaci]]. | ||
*Trachoma caused by Chlamydia trachomatis, although the infectious agent is not always eliminated, as judged by immunofluorescence. | *[[Trachoma]] caused by [[Chlamydia trachomatis]], although the infectious agent is not always eliminated, as judged by immunofluorescence. | ||
*Inclusion conjunctivitis caused by Chlamydia trachomatis. | *Inclusion conjunctivitis caused by [[Chlamydia trachomatis]]. | ||
*Uncomplicated urethral, endocervical, or rectal infections in adults caused by Chlamydia trachomatis. | *Uncomplicated urethral, endocervical, or rectal infections in adults caused by [[Chlamydia trachomatis]]. | ||
*Nongonococcal urethritis caused by Ureaplasma urealyticum. | *Nongonococcal urethritis caused by Ureaplasma urealyticum. | ||
*Relapsing fever due to Borrelia recurrentis. | *[[Relapsing fever]] due to [[Borrelia recurrentis]]. | ||
Doxycycline is also indicated for the treatment of infections caused by the following gram-negative microorganisms: | Doxycycline is also indicated for the treatment of infections caused by the following gram-negative microorganisms: | ||
*Chancroid caused by Haemophilus ducreyi. | *[[Chancroid]] caused by [[Haemophilus ducreyi]]. | ||
*Plague due to Yersinia pestis. | *[[Plague]] due to [[Yersinia pestis]]. | ||
*Tularemia due to Francisella tularensis. | *[[Tularemia]] due to [[Francisella tularensis]]. | ||
*Cholera caused by Vibrio cholerae. | *[[Cholera]] caused by [[Vibrio cholerae]]. | ||
*Campylobacter fetus infections caused by Campylobacter fetus (formerly Vibrio fetus). | *[[Campylobacter]] fetus infections caused by Campylobacter fetus (formerly Vibrio fetus). | ||
*Brucellosis due to Brucella species (in conjunction with streptomycin). | *[[Brucellosis]] due to Brucella species (in conjunction with streptomycin). | ||
*Bartonellosis due to Bartonella bacilliformis. | *[[Bartonellosis]] due to Bartonella bacilliformis. | ||
*Granuloma inguinale caused by Calymmatobacterium granulomatis. | *[[Granuloma inguinale]] caused by [[Calymmatobacterium granulomatis]]. | ||
Because many strains of the following groups of microorganisms have been shown to be resistant to doxycycline, culture and susceptibility testing are recommended. | Because many strains of the following groups of microorganisms have been shown to be resistant to doxycycline, culture and susceptibility testing are recommended. | ||
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Doxycycline is indicated for treatment of infections caused by the following gram-negative bacteria, when bacteriologic testing indicates appropriate susceptibility to the drug: | Doxycycline is indicated for treatment of infections caused by the following gram-negative bacteria, when bacteriologic testing indicates appropriate susceptibility to the drug: | ||
*Escherichia coli. | *[[Escherichia coli]]. | ||
*Enterobacter aerogenes (formerly Aerobacter aerogenes). | *[[Enterobacter aerogenes]] (formerly Aerobacter aerogenes). | ||
*Shigella species. | *[[Shigella species]]. | ||
*Acinetobacter species. | *[[Acinetobacter species]]. | ||
*Respiratory tract infections caused by Haemophilus influenzae. | *Respiratory tract infections caused by [[Haemophilus influenzae]]. | ||
*Respiratory tract and urinary tract infections caused by Klebsiella species. | *Respiratory tract and urinary tract infections caused by [[Klebsiella species]]. | ||
Doxycycline is indicated for treatment of infections caused by the following gram-positive microorganisms when bacteriologic testing indicates appropriate susceptibility to the drug: | Doxycycline is indicated for treatment of infections caused by the following gram-positive microorganisms when bacteriologic testing indicates appropriate susceptibility to the drug: | ||
*Upper respiratory infections caused by Streptococcus pneumoniae (formerly Diplococcus pneumoniae). | *Upper respiratory infections caused by [[Streptococcus pneumoniae]] (formerly Diplococcus pneumoniae). | ||
*Anthrax due to Bacillus anthracis, including inhalational anthrax (post-exposure): to reduce the incidence or progression of disease following exposure to aerosolized Bacillus anthracis. | *[[Anthrax]] due to [[Bacillus anthracis]], including inhalational anthrax (post-exposure): to reduce the incidence or progression of disease following exposure to aerosolized Bacillus anthracis. | ||
When penicillin is contraindicated, doxycycline is an alternative drug in the treatment of the following infections: | When penicillin is contraindicated, doxycycline is an alternative drug in the treatment of the following infections: | ||
*Uncomplicated gonorrhea caused by Neisseria gonorrhoeae. | *Uncomplicated [[gonorrhea]] caused by [[Neisseria gonorrhoeae]]. | ||
*Syphilis caused by Treponema pallidum. | *[[Syphilis]] caused by [[Treponema pallidum]]. | ||
*Yaws caused by Treponema pertenue. | *[[Yaws]] caused by [[Treponema pertenue]]. | ||
* | *[[Listeriosis]] due to [[Listeria monocytogenes]]. | ||
*Vincent's infection caused by Fusobacterium fusiforme. | *Vincent's infection caused by [[Fusobacterium fusiforme]]. | ||
*Actinomycosis caused by Actinomyces israelii. | *[[Actinomycosis]] caused by [[Actinomyces israelii]]. | ||
*Infections caused by Clostridium species. | *Infections caused by [[Clostridium species]]. | ||
In acute intestinal amebiasis, doxycycline may be a useful adjunct to amebicides. | In acute intestinal amebiasis, doxycycline may be a useful adjunct to amebicides. | ||
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'''Prophylaxis''' | '''Prophylaxis''' | ||
Doxycycline is indicated for the prophylaxis of malaria due to Plasmodium falciparum in short-term travelers (<4 months) to areas with chloroquine and/or pyrimethamine-sulfadoxine resistant strains. (See DOSAGE AND ADMINISTRATION section and Information for Patients subsection of the PRECAUTIONS section.) | Doxycycline is indicated for the prophylaxis of malaria due to Plasmodium falciparum in short-term travelers (<4 months) to areas with chloroquine and/or pyrimethamine-sulfadoxine resistant strains. (See DOSAGE AND ADMINISTRATION section and Information for Patients subsection of the PRECAUTIONS section.)<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = VIBRAMYCIN MONOHYDRATE (DOXYCYCLINE) POWDER, FOR SUSPENSION VIBRAMYCIN CALCIUM (DOXYCYCLINE CALCIUM) SYRUP VIBRAMYCIN HYCLATE (DOXYCYCLINE HYCLATE) CAPSULE VIBRA-TABS (DOXYCYCLINE HYCLATE) TABLET, FILM COATED [PFIZER LABORATORIES DIV PFIZER INC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d6f98d3c-5a20-4cbf-9a9c-abef10b9e465#nlm34089-3 | publisher = | date = | accessdate}}</ref> | ||
==References== | |||
{{Reflist}} | |||
{{FDA}} | |||
[[Category:Antibiotics]] | |||
[[Category:Wikinfect]] | |||
Latest revision as of 23:56, 8 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Indications and Usage
To reduce the development of drug-resistant bacteria and maintain effectiveness of Vibramycin and other antibacterial drugs, Vibramycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Treatment
Doxycycline is indicated for the treatment of the following infections:
- Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae.
- Respiratory tract infections caused by Mycoplasma pneumoniae.
- Lymphogranuloma venereum caused by Chlamydia trachomatis.
- Psittacosis (ornithosis) caused by Chlamydophila psittaci.
- Trachoma caused by Chlamydia trachomatis, although the infectious agent is not always eliminated, as judged by immunofluorescence.
- Inclusion conjunctivitis caused by Chlamydia trachomatis.
- Uncomplicated urethral, endocervical, or rectal infections in adults caused by Chlamydia trachomatis.
- Nongonococcal urethritis caused by Ureaplasma urealyticum.
- Relapsing fever due to Borrelia recurrentis.
Doxycycline is also indicated for the treatment of infections caused by the following gram-negative microorganisms:
- Chancroid caused by Haemophilus ducreyi.
- Plague due to Yersinia pestis.
- Tularemia due to Francisella tularensis.
- Cholera caused by Vibrio cholerae.
- Campylobacter fetus infections caused by Campylobacter fetus (formerly Vibrio fetus).
- Brucellosis due to Brucella species (in conjunction with streptomycin).
- Bartonellosis due to Bartonella bacilliformis.
- Granuloma inguinale caused by Calymmatobacterium granulomatis.
Because many strains of the following groups of microorganisms have been shown to be resistant to doxycycline, culture and susceptibility testing are recommended.
Doxycycline is indicated for treatment of infections caused by the following gram-negative bacteria, when bacteriologic testing indicates appropriate susceptibility to the drug:
- Escherichia coli.
- Enterobacter aerogenes (formerly Aerobacter aerogenes).
- Shigella species.
- Acinetobacter species.
- Respiratory tract infections caused by Haemophilus influenzae.
- Respiratory tract and urinary tract infections caused by Klebsiella species.
Doxycycline is indicated for treatment of infections caused by the following gram-positive microorganisms when bacteriologic testing indicates appropriate susceptibility to the drug:
- Upper respiratory infections caused by Streptococcus pneumoniae (formerly Diplococcus pneumoniae).
- Anthrax due to Bacillus anthracis, including inhalational anthrax (post-exposure): to reduce the incidence or progression of disease following exposure to aerosolized Bacillus anthracis.
When penicillin is contraindicated, doxycycline is an alternative drug in the treatment of the following infections:
- Uncomplicated gonorrhea caused by Neisseria gonorrhoeae.
- Syphilis caused by Treponema pallidum.
- Yaws caused by Treponema pertenue.
- Listeriosis due to Listeria monocytogenes.
- Vincent's infection caused by Fusobacterium fusiforme.
- Actinomycosis caused by Actinomyces israelii.
- Infections caused by Clostridium species.
In acute intestinal amebiasis, doxycycline may be a useful adjunct to amebicides.
In severe acne, doxycycline may be useful adjunctive therapy.
Prophylaxis
Doxycycline is indicated for the prophylaxis of malaria due to Plasmodium falciparum in short-term travelers (<4 months) to areas with chloroquine and/or pyrimethamine-sulfadoxine resistant strains. (See DOSAGE AND ADMINISTRATION section and Information for Patients subsection of the PRECAUTIONS section.)[1]
References
Adapted from the FDA Package Insert.