Hand-foot-and-mouth disease laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Physical examination is usually diagnostic for hand foot and mouth disease. However, throat swabs, swabs from the lesion and Tzanck test can be used in diagnosing HFMD.

Laboratory Findings

• Throat swabs or swabs from the lesions can be sent for culture of virus or other immunological studies. Since the testing often takes 2 to 4 weeks to obtain a final answer, the physician usually does not order these tests.
• Tzanck test may be performed to exclude herpes simplex infection.