Coronary heart disease risk factors: Difference between revisions

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==Overview==
==Overview==


==Risk factors==
==Risk Equivalents in Primary Prevention==
'''The following are confirmed independent risk factors for the development of CAD, in order of decreasing importance:'''
You are essentially considered to have the equivalent of coronary heart disease if you have any of the following:
# [[Hypercholesterolemia]] (specifically, serum [[LDL]] concentrations)
*[[Aortic aneurysm]]
# [[tobacco smoking|Smoking]]
*[[Diabetes]]
# [[Hypertension]] (high systolic pressure seems to be most significant in this regard)
*[[Framingham Risk Score]] ([[FRS]]) of > 20%
# [[Hyperglycemia]] (due to diabetes mellitus or otherwise)
*[[Peripheral vascular disease]] ([[PVD]]) (defined as [[claudication]], an [[Ankle Brachial Index]] ([[ABI]]) of < 0.9)
# [[Type A personality |Type A Behavioural Patterns, TABP]]. Added in 1981 as an independant risk factor after a majority of research into the field discovered that TABP's were twice as likely to cause CHD than any other personality type.
*Symptomatic [[carotid artery disease]] (defined as prior [[stroke]] or [[TIA]])
# Hereditary differences in such diverse aspects as lipoprotein structure and that of their associated receptors, homocysteine processing/metabolism, etc.


'''Significant, but indirect risk factors include:'''
==CV Risk Factors in the Setting of Primary Prevention==
* Lack of exercise
* [[Cigarette smoking]]
* Stress
* Family history of premature [[coronary artery disease]] ([[CAD]])
* Diet rich in [[saturated fat]]s
* High [[LDL]] (defined as LDL > 130 mg /dl)
* Diet low in [[antioxidant]]s
* [[Hypertension]] ( defined as a BP ≥140/90 mm Hg or if the patient is on antihypertensive drugs)
* [[Obesity]]
* Low [[HDL]] (defined as HDL < 40 mg/dL males, < 50 mg/dL in females)
* Men over 60; Women over 65 [http://findarticles.com/p/articles/mi_m0857/is_n6_v13/ai_17942856]
* Older Age (men ≥45 years old; women ≥55 years old)


== Complete List of Cardiac Risk Factors ==
== Complete List of Cardiac Risk Factors ==


In alphabetical order. <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>
In alphabetical order: <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>


* ACE DD genotype
* [[ACE]] DD genotype
* Age
* Age
*:* Men > 45
*:* Men > 45
*:* Women > 45 (early [[menopause]])
*:* Women > 45 (early [[menopause]])
*:* Women > 55 (normal onset [[menopause]])
*:* Women > 55 (normal onset [[menopause]])
* [[Alcohol]]
* [[Chronic obstructive lung disease]] ([[COPD]])
* [[Chronic Renal Failure]]
* [[Chronic Renal Failure]]
* [[Cigarette smoking]]
* [[Cigarette smoking]]
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* [[Immunosuppressive posttransplant]]
* [[Immunosuppressive posttransplant]]
* Increased [[apolipoprotein B]]
* Increased [[apolipoprotein B]]
* Increased [[Ddx:C-Reactive Protein|C-reactive protein]]
* Increased [[C-reactive protein]]
* Increased [[Ddx:Fibrinogen|fibrinogen]]
* Increased [[Fibrinogen|fibrinogen]]
* [[Infection]]s
* [[Infection]]s
* [[Insulin resistance]] syndrome
* [[Insulin resistance]] syndrome
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* [[LDL cholesterol]] < 40 mg/dl
* [[LDL cholesterol]] < 40 mg/dl
* [[Low birth weight]]
* [[Low birth weight]]
* [[Metabolic syndrome]]
* [[Obesity]]
* [[Obesity]]
* [[Oral contraceptive]] use
* [[Oral contraceptive]] use
* [[Sedentary living]]
* [[Sedentary living]]
* [[Syndrome X]]
* [[Syndrome X]]
* <u>Type A personality</u>
* Type A personality


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 02:46, 1 October 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Risk Equivalents in Primary Prevention

You are essentially considered to have the equivalent of coronary heart disease if you have any of the following:

CV Risk Factors in the Setting of Primary Prevention

  • Cigarette smoking
  • Family history of premature coronary artery disease (CAD)
  • High LDL (defined as LDL > 130 mg /dl)
  • Hypertension ( defined as a BP ≥140/90 mm Hg or if the patient is on antihypertensive drugs)
  • Low HDL (defined as HDL < 40 mg/dL males, < 50 mg/dL in females)
  • Older Age (men ≥45 years old; women ≥55 years old)

Complete List of Cardiac Risk Factors

In alphabetical order: [1] [2]

References

  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X