Third degree AV block laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory studies are warranted to diagnose etiologies of secondary heart block such as infections (either bacterial or viral), drug toxicity, and electrolyte abnormalities, and to screen for coincident problems that might either cause or exacerbate a previously presented compensated heart block. | Laboratory studies are warranted to diagnose etiologies of secondary heart block such as infections (either bacterial or viral), [[drug toxicity]], and electrolyte abnormalities, and to screen for coincident problems that might either cause or exacerbate a previously presented compensated heart block. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
There are plenty of diagnostic laboratory findings associated with third degree AV block. Laboratory studies are warranted to diagnose etiologies of secondary heart block such as infections (either bacterial or viral), drug toxicity, and electrolyte abnormalities, and to screen for coincident problems that might either cause or exacerbate a previously presented compensated heart block. | There are plenty of diagnostic laboratory findings associated with [[third degree AV block]]. Laboratory studies are warranted to diagnose etiologies of secondary heart block such as infections (either bacterial or viral), [[drug toxicity]], and electrolyte abnormalities, and to screen for coincident problems that might either cause or exacerbate a previously presented compensated heart block. | ||
Primary lab work up of patients with third degree AV block might include but not limitted to the followings: | Primary lab work up of patients with [[third degree AV block]] might include but not limitted to the followings: | ||
*[[Complete blood count]] - may reveal [[anemia]] (low RBC count), [[infection]] ([[leukocytosis]] is seen in [[myocarditis]], [[acute rheumatic fever]] and viral infections) | *[[Complete blood count]] - may reveal [[anemia]] (low RBC count), [[infection]] ([[leukocytosis]] is seen in [[myocarditis]], [[acute rheumatic fever]] and viral infections) | ||
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* Myocarditis related studies - HIV serologies, Lyme serology, Chagas serology, enterovirus PCR, adenovirus [[PCR]] | * Myocarditis related studies - HIV serologies, Lyme serology, Chagas serology, enterovirus PCR, adenovirus [[PCR]] | ||
* Peripheral blood smears can aid in the diagnosis of hematological disorders like [[thalassemia major]], [[Hodgkins lymphoma]] etc., | * Peripheral blood smears can aid in the diagnosis of hematological disorders like [[thalassemia major]], [[Hodgkins lymphoma]] etc., | ||
*In patients with concerning history, toxicological studies for digoxin-like compounds such as: | *In patients with concerning history, toxicological studies for [[digoxin]]-like compounds such as: | ||
:*lily of the valley | :*lily of the valley | ||
:*Oleander | :*Oleander | ||
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:*Bufonidae toads | :*Bufonidae toads | ||
* Cardiac enzyme levels: if history or ECG findings are suggestive of active coronary artery disease. | * Cardiac enzyme levels: if history or [[ECG]] findings are suggestive of active coronary artery disease. | ||
==References== | ==References== | ||
Revision as of 14:19, 20 June 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2] Raviteja Guddeti, M.B.B.S. [3]
Overview
Laboratory studies are warranted to diagnose etiologies of secondary heart block such as infections (either bacterial or viral), drug toxicity, and electrolyte abnormalities, and to screen for coincident problems that might either cause or exacerbate a previously presented compensated heart block.
Laboratory Findings
There are plenty of diagnostic laboratory findings associated with third degree AV block. Laboratory studies are warranted to diagnose etiologies of secondary heart block such as infections (either bacterial or viral), drug toxicity, and electrolyte abnormalities, and to screen for coincident problems that might either cause or exacerbate a previously presented compensated heart block.
Primary lab work up of patients with third degree AV block might include but not limitted to the followings:
- Complete blood count - may reveal anemia (low RBC count), infection (leukocytosis is seen in myocarditis, acute rheumatic fever and viral infections)
- Differential count
- Serum electrolytes: Particularely hyperkalemia and magnesium spescially in selected patients such as those with renal insufficiency
- PT and aPTT may be ordered routinely
- Blood Digoxin levels should be measured in case of digoxin overdose
- Myocarditis related studies - HIV serologies, Lyme serology, Chagas serology, enterovirus PCR, adenovirus PCR
- Peripheral blood smears can aid in the diagnosis of hematological disorders like thalassemia major, Hodgkins lymphoma etc.,
- In patients with concerning history, toxicological studies for digoxin-like compounds such as:
- lily of the valley
- Oleander
- Foxglove
- Bufonidae toads
- Cardiac enzyme levels: if history or ECG findings are suggestive of active coronary artery disease.