Autoimmune hemolytic anemia differential diagnosis: Difference between revisions
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|Microangiopathic hemolytic anemia | |Microangiopathic hemolytic anemia | ||
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* [[Thrombotic thrombocytopenia purpura]] | |||
* [[Hemolytic uremic syndrome]] | |||
* [[Disseminated intravascular coagulation]] | |||
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* [[ | |||
* [[ | |||
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* | * Formation of small vessel microthombi | ||
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* [[Schistocytes]] on peripheral blood smear | * [[Schistocytes]] on peripheral blood smear | ||
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* Treatment of the underlying cause | * Treatment of the underlying cause | ||
* Plasmapheresis if [[thrombotic thrombocytopenia purpura]] | * Plasmapheresis if [[thrombotic thrombocytopenia purpura]] is the underlying cause | ||
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* Can be life-threatening pending the underlying cause | * Can be life-threatening pending the underlying cause |
Revision as of 18:58, 12 April 2018
Autoimmune hemolytic anemia Microchapters |
Differentiating Autoimmune hemolytic anemia from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S; Shyam Patel [2]
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Overview
Differentiating Autoimmune hemolytic anemia from other Diseases
Diagnosis is made by first ruling out other causes of hemolytic anemia, such as G6PD, thalassemia, sickle-cell disease, etc.
Characteristic | Causes | Pathophysiology | Laboratory abnormalities | Physical examination | Therapy | Other associations |
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Autoimmune hemolytic anemia |
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Microangiopathic hemolytic anemia |
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Paroxysmal cold hemoglobinuria |
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Paroxysmal nocturnal hemoglobinuria |
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Hereditary spherocytosis[3] |
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Pernicious anemia[4] |
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Chronic lymphocytic leukemia[5] |
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References
- ↑ 1.0 1.1 1.2 Berentsen S, Sundic T (2015). "Red blood cell destruction in autoimmune hemolytic anemia: role of complement and potential new targets for therapy". Biomed Res Int. 2015: 363278. doi:10.1155/2015/363278. PMC 4326213. PMID 25705656.
- ↑ 2.0 2.1 2.2 2.3 Akpoguma AO, Carlisle TL, Lentz SR (2015). "Case report: paroxysmal cold hemoglobinuria presenting during pregnancy". BMC Hematol. 15: 3. doi:10.1186/s12878-015-0023-7. PMC 4334594. PMID 25699184.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Gallagher PG (2013). "Abnormalities of the erythrocyte membrane". Pediatr Clin North Am. 60 (6): 1349–62. doi:10.1016/j.pcl.2013.09.001. PMC 4155395. PMID 24237975.
- ↑ 4.0 4.1 4.2 4.3 4.4 Chan CQ, Low LL, Lee KH (2016). "Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia". Front Med (Lausanne). 3: 38. doi:10.3389/fmed.2016.00038. PMC 4993789. PMID 27602354.
- ↑ Kipps TJ, Stevenson FK, Wu CJ, Croce CM, Packham G, Wierda WG; et al. (2017). "Chronic lymphocytic leukaemia". Nat Rev Dis Primers. 3: 16096. doi:10.1038/nrdp.2016.96. PMC 5336551. PMID 28102226.