Gallstone disease other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Bile microscopy has been largely replaced by transabdominal ultrasound, however it may be helpful in evaluating obese patients. | Bile microscopy has been largely replaced by transabdominal [[ultrasound]], however it may be helpful in evaluating [[Obesity|obese]] patients. | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
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===Bile microscopy=== | ===Bile microscopy=== | ||
Patients whom exhibit symptoms of biliary colic where ultrasound fails to detect stones often turn to microscopic analysis of their bile as proof of microlithiasis. It has an overall sensitivity of 65 to 90 percent for identifying patients with gallstones.<ref name="pmid3943777">{{cite journal |vauthors=Delchier JC, Benfredj P, Preaux AM, Metreau JM, Dhumeaux D |title=The usefulness of microscopic bile examination in patients with suspected microlithiasis: a prospective evaluation |journal=Hepatology |volume=6 |issue=1 |pages=118–22 |year=1986 |pmid=3943777 |doi= |url=}}</ref><ref name="pmid3706246">{{cite journal |vauthors=Moskovitz M, Min TC, Gavaler JS |title=The microscopic examination of bile in patients with biliary pain and negative imaging tests |journal=Am. J. Gastroenterol. |volume=81 |issue=5 |pages=329–33 |year=1986 |pmid=3706246 |doi= |url=}}</ref> The test detects traces of cholesterol crystals or bilirubinate granules. A high number of patients whom had clear ultrasounds had positive results on microscopy, however, the high sensitivity of tranabdominal ultrasonography has made the need for microscopy rare. <ref name="pmid7366692">{{cite journal |vauthors=Sedaghat A, Grundy SM |title=Cholesterol crystals and the formation of cholesterol gallstones |journal=N. Engl. J. Med. |volume=302 |issue=23 |pages=1274–7 |year=1980 |pmid=7366692 |doi=10.1056/NEJM198006053022302 |url=}}</ref><ref name="pmid6884818">{{cite journal |vauthors=Gollish SH, Burnstein MJ, Ilson RG, Petrunka CN, Strasberg SM |title=Nucleation of cholesterol monohydrate crystals from hepatic and gall-bladder bile of patients with cholesterol gall stones |journal=Gut |volume=24 |issue=9 |pages=836–44 |year=1983 |pmid=6884818 |pmc=1420078 |doi= |url=}}</ref> | Patients whom exhibit symptoms of [[Gallstone disease history and symptoms|biliary colic]] where [[ultrasound]] fails to detect stones often turn to microscopic analysis of their bile as proof of microlithiasis. It has an overall sensitivity of 65 to 90 percent for identifying patients with gallstones.<ref name="pmid3943777">{{cite journal |vauthors=Delchier JC, Benfredj P, Preaux AM, Metreau JM, Dhumeaux D |title=The usefulness of microscopic bile examination in patients with suspected microlithiasis: a prospective evaluation |journal=Hepatology |volume=6 |issue=1 |pages=118–22 |year=1986 |pmid=3943777 |doi= |url=}}</ref><ref name="pmid3706246">{{cite journal |vauthors=Moskovitz M, Min TC, Gavaler JS |title=The microscopic examination of bile in patients with biliary pain and negative imaging tests |journal=Am. J. Gastroenterol. |volume=81 |issue=5 |pages=329–33 |year=1986 |pmid=3706246 |doi= |url=}}</ref> The test detects traces of [[cholesterol]] crystals or [[Bilirubin|bilirubinate]] granules. A high number of patients whom had clear ultrasounds had positive results on microscopy, however, the high [[Sensitivity (tests)|sensitivity]] of tranabdominal [[Medical ultrasonography|ultrasonography]] has made the need for microscopy rare. <ref name="pmid7366692">{{cite journal |vauthors=Sedaghat A, Grundy SM |title=Cholesterol crystals and the formation of cholesterol gallstones |journal=N. Engl. J. Med. |volume=302 |issue=23 |pages=1274–7 |year=1980 |pmid=7366692 |doi=10.1056/NEJM198006053022302 |url=}}</ref><ref name="pmid6884818">{{cite journal |vauthors=Gollish SH, Burnstein MJ, Ilson RG, Petrunka CN, Strasberg SM |title=Nucleation of cholesterol monohydrate crystals from hepatic and gall-bladder bile of patients with cholesterol gall stones |journal=Gut |volume=24 |issue=9 |pages=836–44 |year=1983 |pmid=6884818 |pmc=1420078 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
Revision as of 18:31, 1 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Bile microscopy has been largely replaced by transabdominal ultrasound, however it may be helpful in evaluating obese patients.
Other Imaging Findings
Bile microscopy
Patients whom exhibit symptoms of biliary colic where ultrasound fails to detect stones often turn to microscopic analysis of their bile as proof of microlithiasis. It has an overall sensitivity of 65 to 90 percent for identifying patients with gallstones.[1][2] The test detects traces of cholesterol crystals or bilirubinate granules. A high number of patients whom had clear ultrasounds had positive results on microscopy, however, the high sensitivity of tranabdominal ultrasonography has made the need for microscopy rare. [3][4]
References
- ↑ Delchier JC, Benfredj P, Preaux AM, Metreau JM, Dhumeaux D (1986). "The usefulness of microscopic bile examination in patients with suspected microlithiasis: a prospective evaluation". Hepatology. 6 (1): 118–22. PMID 3943777.
- ↑ Moskovitz M, Min TC, Gavaler JS (1986). "The microscopic examination of bile in patients with biliary pain and negative imaging tests". Am. J. Gastroenterol. 81 (5): 329–33. PMID 3706246.
- ↑ Sedaghat A, Grundy SM (1980). "Cholesterol crystals and the formation of cholesterol gallstones". N. Engl. J. Med. 302 (23): 1274–7. doi:10.1056/NEJM198006053022302. PMID 7366692.
- ↑ Gollish SH, Burnstein MJ, Ilson RG, Petrunka CN, Strasberg SM (1983). "Nucleation of cholesterol monohydrate crystals from hepatic and gall-bladder bile of patients with cholesterol gall stones". Gut. 24 (9): 836–44. PMC 1420078. PMID 6884818.