Differentiating Hirschsprung's Disease from other Diseases: Difference between revisions
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|Meconium plug syndrome | |Meconium plug syndrome | ||
|Transient intestinal obstruction for 1-2 days after birth. | | | ||
Obstruction is functional due to dilated colon and delayed passage of faeces. | * Transient intestinal obstruction for 1-2 days after birth. | ||
Usually seen in premature infants. | * Obstruction is functional due to dilated colon and delayed passage of faeces. | ||
* Usually seen in premature infants. | |||
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|Small left colon syndrome | |Small left colon syndrome | ||
|Reduced caliber of the colon starting from splenic flexure and going down causing intestinal obstruction. | | | ||
Characterized by sudden change of the diameter of the colon. | * Reduced caliber of the colon starting from splenic flexure and going down causing intestinal obstruction. | ||
Usually associated with gestational diabetes. | * Characterized by sudden change of the diameter of the colon. | ||
* Usually associated with gestational diabetes. | |||
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|Distal small bowel /colonic atresia | |Distal small bowel /colonic atresia | ||
|Failure to pass meconium due to failure of recanalization of the intestine. | | | ||
Proximal lesions has earlier earlier onset of symptoms than distal lesions. | * Failure to pass meconium due to failure of recanalization of the intestine. | ||
Colonic atresia may affect normal children or may be associated with other abnormalities as Hirschsprung disease or gastroschisis. | * Proximal lesions has earlier earlier onset of symptoms than distal lesions. | ||
* Colonic atresia may affect normal children or may be associated with other abnormalities as Hirschsprung disease or gastroschisis. | |||
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|Meconium ileus | |Meconium ileus | ||
|Intestinal obstruction due to inspissation of meconium in the distal ileum. | | | ||
Most cases of meconium ileus are secondary to cystic fibrosis. | * Intestinal obstruction due to inspissation of meconium in the distal ileum. | ||
Typically presents with failure to pass meconium, abdominal distension with or without vomiting. | * Most cases of meconium ileus are secondary to cystic fibrosis. | ||
Meconium ileus may first present with complications perforation and volvolus. | * Typically presents with failure to pass meconium, abdominal distension with or without vomiting. | ||
* Meconium ileus may first present with complications perforation and volvolus. | |||
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|Congenital hypothyroidism | |Congenital hypothyroidism | ||
|Most infants are born asymptomatic. | |*Most infants are born asymptomatic. | ||
Macroglossia | *Macroglossia | ||
Hoarse cry | *Hoarse cry | ||
Umbilical hernia | *Umbilical hernia | ||
Puffy facies | *Puffy facies | ||
Increased head circumference | *Increased head circumference | ||
Hypothermia | *Hypothermia | ||
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Revision as of 16:09, 15 June 2017
Hirschsprung's disease Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Hirschsprung disease must be differentiated from other diseases that cause failure to pass meconium and abdominal distension in infants, such as meconium plug syndrome, small left colon syndrome and congenital hypothyroidism.
Differential Diagnosis
Hirschprung's disease must be differentiated from other diseases in infancy presenting with similar features such as failure to pass meconium, abdominal distention and non-bilious vomiting.
- Meconium plug syndrome
- Small left colon syndrome
- Distal small bowel /colonic atresia
- Meconium ileus and cystic fibrosis complex
- Congenital hypothyroidism
Disease | Prominent clinical features | Radiologiacal findings |
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Meconium plug syndrome |
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Small left colon syndrome |
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Distal small bowel /colonic atresia |
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Meconium ileus |
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Congenital hypothyroidism | *Most infants are born asymptomatic.
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