Pott's disease differential diagnosis: Difference between revisions
| Line 10: | Line 10: | ||
==Differentiating Pott's Disease from other Diseases== | ==Differentiating Pott's Disease from other Diseases== | ||
Pott's disease resembles the following disorders and needs to be differentiated from them: | Pott's disease resembles the following disorders and needs to be differentiated from them: | ||
{| class="wikitable" | |||
!Disease | |||
!Age of Presentation | |||
!Common site involved | |||
!Risk Factors | |||
!Clinical Features | |||
!Laboratory Findings | |||
!Imaging Findings | |||
|- | |||
|Pyogenic Abscess | |||
of the spine | |||
|Any age | |||
|Lumbar | |||
|Systemic illnesses like diabetes mellitus | |||
|Fever and marked back pain, myelopathy | |||
|Elevated ESR | |||
Elevated WBC's | |||
Elevated CRP | |||
|Destruction of vertebral bodies and disc spaces, marked enhancement of the lesion, epidural abscess | |||
|- | |||
|Pott's Disease | |||
|Children and adults | |||
|Lumbo-thoracic | |||
|Exposure to tuberculous infection | |||
|Fever, malaise and weight loss, backache, myelopathy | |||
|Elevated ESR | |||
Normal WBC | |||
|Destruction of vertebral bodies and disc spaces, rim enhancement of the soft-tissue masses | |||
|- | |||
|Brucella abscess | |||
of the spine | |||
|Adults | |||
|Lumbar | |||
|Ingestion of unpasteurized milk | |||
|Fever, malaise, weight loss, backache | |||
|Elevated ESR | |||
Elevated WBC | |||
Elevated CRP | |||
|Intact vertebral architecture despite diffuse vertebral osteomyelitis | |||
|- | |||
|Vertebral Metastasis | |||
|Elderly | |||
|Thoracic | |||
|Presence of systemic malignancy | |||
|Bone pain at night, backache, back pain followed by radicular pain, myelopathy | |||
|Normal WBC, ESR and CRP | |||
|Low signal intensity on T1-weighted images, hypersignal on T2-weighted images and heterogeneous enhancement | |||
|} | |||
*[[Spinal tumor]]s | *[[Spinal tumor]]s | ||
*Spinal cord [[abscess]] | *Spinal cord [[abscess]] | ||
Revision as of 18:17, 28 March 2017
|
Pott's disease Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Pott's disease differential diagnosis On the Web |
|
American Roentgen Ray Society Images of Pott's disease differential diagnosis |
|
Risk calculators and risk factors for Pott's disease differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hardik Patel, M.D.
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
Pott's disease resembles spinal tumors, spinal cord abscess, Mycobacterium kansasii, nocardiosis, septic arthritis, metastatic cancer, multiple myeloma, miliary tuberculosis, spinal fungal infections, and Mycobacterium avium-intracellulare and needs to be differentiated from them.
Differentiating Pott's Disease from other Diseases
Pott's disease resembles the following disorders and needs to be differentiated from them:
| Disease | Age of Presentation | Common site involved | Risk Factors | Clinical Features | Laboratory Findings | Imaging Findings |
|---|---|---|---|---|---|---|
| Pyogenic Abscess
of the spine |
Any age | Lumbar | Systemic illnesses like diabetes mellitus | Fever and marked back pain, myelopathy | Elevated ESR
Elevated WBC's Elevated CRP |
Destruction of vertebral bodies and disc spaces, marked enhancement of the lesion, epidural abscess |
| Pott's Disease | Children and adults | Lumbo-thoracic | Exposure to tuberculous infection | Fever, malaise and weight loss, backache, myelopathy | Elevated ESR
Normal WBC |
Destruction of vertebral bodies and disc spaces, rim enhancement of the soft-tissue masses |
| Brucella abscess
of the spine |
Adults | Lumbar | Ingestion of unpasteurized milk | Fever, malaise, weight loss, backache | Elevated ESR
Elevated WBC Elevated CRP |
Intact vertebral architecture despite diffuse vertebral osteomyelitis |
| Vertebral Metastasis | Elderly | Thoracic | Presence of systemic malignancy | Bone pain at night, backache, back pain followed by radicular pain, myelopathy | Normal WBC, ESR and CRP | Low signal intensity on T1-weighted images, hypersignal on T2-weighted images and heterogeneous enhancement |
- Spinal tumors
- Spinal cord abscess
- Mycobacterium kansasii
- Nocardiosis
- Paracoccidioidomycosis
- Septic arthritis
- Metastatic cancer[1]
- Multiple myeloma
- Miliary tuberculosis
- Actinomycosis
- Blastomycosis
- Brucellosis
- Candidiasis
- Cryptococcosis
- Histoplasmosis
- Mycobacterium avium-intracellulare
References
- ↑ Mittal S, Khalid M, Sabir AB, Khalid S (2016). "Comparison of Magnetic Resonance Imaging Findings between Pathologically Proven Cases of Atypical Tubercular Spine and Tumour Metastasis: A Retrospective Study in 40 Patients". Asian Spine J. 10 (4): 734–43. doi:10.4184/asj.2016.10.4.734. PMC 4995258. PMID 27559455.