Endometrial hyperplasia differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Endometrial hyperplasia must be differentiated from conditions that have similar ultrasound appearances such as normal thickening during the secretory phase, sessile endometrial polyp, submucosal uterine | Endometrial hyperplasia must be differentiated from conditions that have similar [[ultrasound]] appearances such as normal thickening during the secretory phase, [[sessile]] [[endometrial polyp]], [[submucosal uterine fibroid]]s, [[endometrial cancer]], adherent intrauterine blood clot,and [[pregnancy]].<ref name="pmid8184058">{{cite journal| author=Hulka CA, Hall DA, McCarthy K, Simeone JF| title=Endometrial polyps, hyperplasia, and carcinoma in postmenopausal women: differentiation with endovaginal sonography. | journal=Radiology | year= 1994 | volume= 191 | issue= 3 | pages= 755-8 | pmid=8184058 | doi=10.1148/radiology.191.3.8184058 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8184058 }} </ref><ref name=wp>Endometrial hyperplasia. Radiopedia. http://radiopaedia.org/articles/endometrial-hyperplasia-1 Accessed on March 3, 2016.</ref><ref name=ol>Abnormally thickened endometrium: differential diagnosis. Radiopedia. http://radiopaedia.org/articles/abnormally-thickened-endometrium-differential-diagnosis Accessed on March 3, 2016.</ref> | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
*Endometrial hyperplasia must be differentiated from the following conditions that have abnormal thickening of the uterus:<ref name="pmid8184058">{{cite journal| author=Hulka CA, Hall DA, McCarthy K, Simeone JF| title=Endometrial polyps, hyperplasia, and carcinoma in postmenopausal women: differentiation with endovaginal sonography. | journal=Radiology | year= 1994 | volume= 191 | issue= 3 | pages= 755-8 | pmid=8184058 | doi=10.1148/radiology.191.3.8184058 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8184058 }} </ref><ref name=wp>Endometrial hyperplasia. Radiopedia. http://radiopaedia.org/articles/endometrial-hyperplasia-1 Accessed on March 3, 2016.</ref><ref name=ol>Abnormally thickened endometrium: differential diagnosis. Radiopedia. http://radiopaedia.org/articles/abnormally-thickened-endometrium-differential-diagnosis Accessed on March 3, 2016.</ref> | *Endometrial hyperplasia must be differentiated from the following conditions that have abnormal thickening of the [[uterus]]:<ref name="pmid8184058">{{cite journal| author=Hulka CA, Hall DA, McCarthy K, Simeone JF| title=Endometrial polyps, hyperplasia, and carcinoma in postmenopausal women: differentiation with endovaginal sonography. | journal=Radiology | year= 1994 | volume= 191 | issue= 3 | pages= 755-8 | pmid=8184058 | doi=10.1148/radiology.191.3.8184058 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8184058 }} </ref><ref name=wp>Endometrial hyperplasia. Radiopedia. http://radiopaedia.org/articles/endometrial-hyperplasia-1 Accessed on March 3, 2016.</ref><ref name=ol>Abnormally thickened endometrium: differential diagnosis. Radiopedia. http://radiopaedia.org/articles/abnormally-thickened-endometrium-differential-diagnosis Accessed on March 3, 2016.</ref> | ||
===Pregnancy related=== | ===Pregnancy related=== | ||
*Early pregnancy prior to sac being visualized (<5 weeks of gestation) | *Early [[pregnancy]] prior to sac being visualized (<5 weeks of gestation) | ||
*Ectopic pregnancy (thickened endometrium and sometimes fluid collection or | *[[Ectopic pregnancy]] (thickened [[endometrium]] and sometimes fluid collection or pseudo[[gestational sac]] can be associated) | ||
*Retained products of conception (heterogeneously thickened endometrium with increased vascularity) | *[[Retained products of conception]] (heterogeneously thickened [[endometrium]] with increased [[vascularity]]) | ||
*Adherent intra-uterine blood clot (heterogeneous endometrium with no vascularity) | *Adherent intra-uterine blood clot (heterogeneous [[endometrium]] with no vascularity) | ||
*Molar pregnancy thickened with multiple small cystic spaces | *[[Molar pregnancy]] thickened with multiple small cystic spaces | ||
*Endometritis (prominent hyperechoic endometrium with of without fluid and debris) | *[[Endometritis]] (prominent hyperechoic [[endometrium]] with of without fluid and debris) | ||
===Non-pregnancy related=== | ===Non-pregnancy related=== | ||
*Endometrial carcinoma (variable appearance) | *[[Endometrial carcinoma]] (variable appearance) | ||
*Endometrial polyp or polyps (usually hyperechoic, often focal, look for vascular stalk) | *Endometrial [[polyp]] or polyps (usually hyperechoic, often focal, look for vascular stalk) | ||
*Submucosal uterine | *[[Submucosal uterine fibroid]]s | ||
*Intrauterine adhesions (irregular echogenic areas with focal thickening) | *Intrauterine adhesions (irregular echogenic areas with focal thickening) | ||
Revision as of 19:21, 16 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Endometrial hyperplasia must be differentiated from conditions that have similar ultrasound appearances such as normal thickening during the secretory phase, sessile endometrial polyp, submucosal uterine fibroids, endometrial cancer, adherent intrauterine blood clot,and pregnancy.[1][2][3]
Differential Diagnosis
- Endometrial hyperplasia must be differentiated from the following conditions that have abnormal thickening of the uterus:[1][2][3]
- Early pregnancy prior to sac being visualized (<5 weeks of gestation)
- Ectopic pregnancy (thickened endometrium and sometimes fluid collection or pseudogestational sac can be associated)
- Retained products of conception (heterogeneously thickened endometrium with increased vascularity)
- Adherent intra-uterine blood clot (heterogeneous endometrium with no vascularity)
- Molar pregnancy thickened with multiple small cystic spaces
- Endometritis (prominent hyperechoic endometrium with of without fluid and debris)
- Endometrial carcinoma (variable appearance)
- Endometrial polyp or polyps (usually hyperechoic, often focal, look for vascular stalk)
- Submucosal uterine fibroids
- Intrauterine adhesions (irregular echogenic areas with focal thickening)
References
- ↑ 1.0 1.1 Hulka CA, Hall DA, McCarthy K, Simeone JF (1994). "Endometrial polyps, hyperplasia, and carcinoma in postmenopausal women: differentiation with endovaginal sonography". Radiology. 191 (3): 755–8. doi:10.1148/radiology.191.3.8184058. PMID 8184058.
- ↑ 2.0 2.1 Endometrial hyperplasia. Radiopedia. http://radiopaedia.org/articles/endometrial-hyperplasia-1 Accessed on March 3, 2016.
- ↑ 3.0 3.1 Abnormally thickened endometrium: differential diagnosis. Radiopedia. http://radiopaedia.org/articles/abnormally-thickened-endometrium-differential-diagnosis Accessed on March 3, 2016.