Endometrial hyperplasia ultrasound

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Swathi Venkatesan, M.B.B.S.[2]

Overview

Pelvic ultrasound on days 5 to 10 of menstrual cycle reduce the variability in endometrial thickness and may be helpful in the diagnosis of endometrial hyperplasia. On pelvic ultrasound, endometrial hyperplasia is characterized by a homogeneous increase in the endometrial thickness in the majority of patients. However, endometrial hyperplasia may also cause asymmetric or focal thickening with surface irregularity which should raise a suspicion for malignancy.[1]

Ultrasound

Premenopausal

Postmenopausal

  • An endometrial thickness of >5 mm is considered abnormal

Tamoxifen associated endometrial changes

  • On pelvic ultrasound, tamoxifen induced endometrial hyperplasia is characterized by thickened, irregular, and cystic endometrium.
  • Changes tend to be subendometrial in location and may cause subendometrial cysts.[3]
  • The degree of endometrial thickening corresponds to the duration of tamoxifen therapy.[3]

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References

  1. 1.0 1.1 1.2 Endometrial hyperplasia. Radiopedia. http://radiopaedia.org/articles/endometrial-hyperplasia-1 Accessed on March 10, 2016.
  2. Jorizzo JR, Chen MY, Martin D, Dyer RB, Weber TM (2002). "Spectrum of endometrial hyperplasia and its mimics on saline hysterosonography". AJR Am J Roentgenol. 179 (2): 385–9. doi:10.2214/ajr.179.2.1790385. PMID 12130438.
  3. 3.0 3.1 Tamoxifen associated endometrial changes. Radiopedia. http://radiopaedia.org/articles/tamoxifen-associated-endometrial-changes Accessed on March 15, 2016.
  4. 4.0 4.1 4.2 4.3 Image courtesy of Dr Maulik S Patel. Radiopaedia (original file ‘’here’’). Creative Commons BY-SA-NC

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