Fibroma pathophysiology: Difference between revisions

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==Pathogenesis==
==Pathogenesis==
 
===Ovarian Fibroma===
* The tumour belongs to the same histopathologic spectrum as an ovarian thecoma / ovarian fibrothecoma. Fibromas have no (or very few) thecal cells and no (or minimal) estrogen activity.
* It is composed of spindle cells forming variable amounts of collagen. Sectioning of a fibroma typically reveals a chalky-white surface that has a whorled appearance, similar to that of a uterine fibroid. Areas of oedema, occasionally with cyst formation, are also relatively common.
==Genetics==
==Genetics==



Revision as of 16:02, 23 February 2016

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Overview

Pathogenesis

Ovarian Fibroma

  • The tumour belongs to the same histopathologic spectrum as an ovarian thecoma / ovarian fibrothecoma. Fibromas have no (or very few) thecal cells and no (or minimal) estrogen activity.
  • It is composed of spindle cells forming variable amounts of collagen. Sectioning of a fibroma typically reveals a chalky-white surface that has a whorled appearance, similar to that of a uterine fibroid. Areas of oedema, occasionally with cyst formation, are also relatively common.

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