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==Classification==
==Classification==
==Trilateral Retinoblastoma==
*Trilateral retinoblastoma<ref name="pmid7900586">{{cite journal |author=Provenzale JM, Weber AL, Klintworth GK, McLendon RE |title=Radiologic-pathologic correlation. Bilateral retinoblastoma with coexistent pinealoblastoma (trilateral retinoblastoma) |journal=[[AJNR. American Journal of Neuroradiology]] |volume=16 |issue=1 |pages=157–65 |year=1995 |month=January |pmid=7900586 |doi= |url=http://www.ajnr.org/cgi/pmidlookup?view=long&pmid=7900586 |accessdate=2012-05-02}}</ref> is the term that refers to bilateral retinoblastoma associated with an intracranial [[primitive neuroectodermal tumor]] in the [[pineal]] or [[suprasellar region]]. It has a poor [[prognosis]] especially when there is [[leptomeningeal]] involvement and when the tumor spreads in to [[subarachnoid space]]. For dissemination of tumor cells into the sub-arachnoid space, [[Optic nerve]] involvement is an important portal.
*The mean length of survival is 9.7 months in patients who undergo treatment and 1.3 months in those who do not after a pineal or sellar mass is detected.<ref name="pmid1985763">{{cite journal |author=Holladay DA, Holladay A, Montebello JF, Redmond KP |title=Clinical presentation, treatment, and outcome of trilateral retinoblastoma |journal=[[Cancer]] |volume=67 |issue=3 |pages=710–5 |year=1991 |month=February |pmid=1985763 |doi= |url= |accessdate=2012-05-02}}</ref>





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Overview

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Trilateral Retinoblastoma

  • Trilateral retinoblastoma[1] is the term that refers to bilateral retinoblastoma associated with an intracranial primitive neuroectodermal tumor in the pineal or suprasellar region. It has a poor prognosis especially when there is leptomeningeal involvement and when the tumor spreads in to subarachnoid space. For dissemination of tumor cells into the sub-arachnoid space, Optic nerve involvement is an important portal.
  • The mean length of survival is 9.7 months in patients who undergo treatment and 1.3 months in those who do not after a pineal or sellar mass is detected.[2]


References

  1. Provenzale JM, Weber AL, Klintworth GK, McLendon RE (1995). "Radiologic-pathologic correlation. Bilateral retinoblastoma with coexistent pinealoblastoma (trilateral retinoblastoma)". AJNR. American Journal of Neuroradiology. 16 (1): 157–65. PMID 7900586. Retrieved 2012-05-02. Unknown parameter |month= ignored (help)
  2. Holladay DA, Holladay A, Montebello JF, Redmond KP (1991). "Clinical presentation, treatment, and outcome of trilateral retinoblastoma". Cancer. 67 (3): 710–5. PMID 1985763. Unknown parameter |month= ignored (help); |access-date= requires |url= (help)

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