Multi-drug-resistant tuberculosis historical perspective: Difference between revisions
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*The rod-shaped bacteria ''[[Mycobacterium tuberculosis]]'' was only identified in 1882 by [[Robert Koch]]. | *The rod-shaped bacteria ''[[Mycobacterium tuberculosis]]'' was only identified in 1882 by [[Robert Koch]]. | ||
*In the 19th and early 20th centuries, [[tuberculosis]] caused the most widespread public concern, being considered an endemic disease of the urban poor. In 1946, the development of [[streptomycin]] made possible the treatment and cure for tuberculosis. | *In the 19th and early 20th centuries, [[tuberculosis]] caused the most widespread public concern, being considered an endemic disease of the urban poor. In 1946, the development of [[streptomycin]] made possible the treatment and cure for tuberculosis. | ||
*During the 1970s, multi-drug resistant mycobacterium tuberculosis was first described. | *During the 1970s, a multi-drug resistant mycobacterium tuberculosis was first described. | ||
*In 1990, the DOTS strategy was first introduced by | *In 1990, the DOTS strategy was first introduced by WHO to prevent patient's drop-out from the medical regimen. | ||
*In 2012, an estimated of 450 000 cases of MDR-TB were reported and there were an estimated 170 000 deaths from MDR-TB.<ref name="WHO report">{{cite web|url=http://www.who.int/tb/publications/global_report/en/ | title= WHO Global Tuberculosis Report 2013}}</ref> | *In 2012, an estimated of 450 000 cases of MDR-TB were reported and there were an estimated 170 000 deaths from MDR-TB.<ref name="WHO report">{{cite web|url=http://www.who.int/tb/publications/global_report/en/ | title= WHO Global Tuberculosis Report 2013}}</ref> | ||
*Also, the WHO reported that 3.6% of newly diagnosed TB cases were drug resistant and 20% of previously treated patients developed multi-drug resistant TB. | *Also, the WHO reported that 3.6% of newly diagnosed TB cases were drug resistant and 20% of previously treated patients developed multi-drug resistant TB. | ||
Revision as of 14:22, 30 September 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Historical Perspective
Images from the History of Medicine (NLM) (http://ihm.nlm.nih.gov/images/B16691)
- Tuberculosis has been present in humans since antiquity. The earliest unambiguous detection of Mycobacterium tuberculosis was in the remains of bison, dated 18,000 BC.[1]
- However, whether tuberculosis originated in cattle and then transferred to humans, or diverged from a common ancestor, is currently unclear.[2]
- Through history tuberculosis had many names, such as phthisis and Wasting disease, which were mostly derived from its symptoms.
- The rod-shaped bacteria Mycobacterium tuberculosis was only identified in 1882 by Robert Koch.
- In the 19th and early 20th centuries, tuberculosis caused the most widespread public concern, being considered an endemic disease of the urban poor. In 1946, the development of streptomycin made possible the treatment and cure for tuberculosis.
- During the 1970s, a multi-drug resistant mycobacterium tuberculosis was first described.
- In 1990, the DOTS strategy was first introduced by WHO to prevent patient's drop-out from the medical regimen.
- In 2012, an estimated of 450 000 cases of MDR-TB were reported and there were an estimated 170 000 deaths from MDR-TB.[3]
- Also, the WHO reported that 3.6% of newly diagnosed TB cases were drug resistant and 20% of previously treated patients developed multi-drug resistant TB.
References
- ↑ Rothschild B, Martin L, Lev G, Bercovier H, Bar-Gal G, Greenblatt C, Donoghue H, Spigelman M, Brittain D (2001). "Mycobacterium tuberculosis complex DNA from an extinct bison dated 17,000 years before the present". Clin Infect Dis. 33 (3): 305–11. PMID 11438894.
- ↑ Pearce-Duvet J (2006). "The origin of human pathogens: evaluating the role of agriculture and domestic animals in the evolution of human disease". Biol Rev Camb Philos Soc. 81 (3): 369–82. PMID 16672105.
- ↑ "WHO Global Tuberculosis Report 2013".