CENPI: Difference between revisions

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Revision as of 09:33, 30 August 2017

Centromere protein I is a protein that in humans is encoded by the CENPI gene.^[1]^[2]

The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.^[2]

References

↑ Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nat Cell Biol. 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.
↑ ^2.0 ^2.1 "Entrez Gene: CENPI centromere protein I".

External links

Human CENPI genome location and CENPI gene details page in the UCSC Genome Browser.

Izuta H, Ikeno M, Suzuki N, et al. (2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells". Genes Cells. 11 (6): 673–84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197.
Foltz DR, Jansen LE, Black BE, et al. (2006). "The human CENP-A centromeric nucleosome-associated complex". Nat. Cell Biol. 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Obuse C, Yang H, Nozaki N, et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase". Genes Cells. 9 (2): 105–20. doi:10.1111/j.1365-2443.2004.00705.x. PMID 15009096.
Liu ST, Hittle JC, Jablonski SA, et al. (2003). "Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis". Nat. Cell Biol. 5 (4): 341–5. doi:10.1038/ncb953. PMID 12640463.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Roberts RG, Kendall E, Vetrie D, Bobrow M (1997). "Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene". Genomics. 37 (1): 122–4. doi:10.1006/geno.1996.0528. PMID 8921378.
Slegtenhorst-Eegdeman KE, Post M, Baarends WM, et al. (1995). "Regulation of gene expression in Sertoli cells by follicle-stimulating hormone (FSH): cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein". Mol. Cell. Endocrinol. 108 (1–2): 115–24. doi:10.1016/0303-7207(94)03468-9. PMID 7758824.
Adams MD, Dubnick M, Kerlavage AR, et al. (1992). "Sequence identification of 2,375 human brain genes". Nature. 355 (6361): 632–4. doi:10.1038/355632a0. PMID 1538749.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

[pmid16622420-1] Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nat Cell Biol. 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.

[entrez-2] 2.0 ^2.1 "Entrez Gene: CENPI centromere protein I".

[1]

[2]

@@ Line 1: / Line 1: @@
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+{{Underlinked|date=May 2014}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''Centromere protein I''' is a [[protein]] that in humans is encoded by the ''CENPI'' [[gene]].<ref name="pmid16622420">{{cite journal | vauthors = Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T | title = The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres | journal = Nat Cell Biol | volume = 8 | issue = 5 | pages = 446–57 |date=May 2006 | pmid = 16622420 | pmc =  | doi = 10.1038/ncb1396 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CENPI centromere protein I| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2491| accessdate = }}</ref>
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-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Centromere protein I
- | HGNCid = 3968
- | Symbol = CENPI
- | AltSymbols =; CENP-I; FSHPRH1; LRPR1; Mis6
- | OMIM = 300065
- | ECnumber =
- | Homologene = 4899
- | MGIid = 2147897
- | GeneAtlas_image1 = PBB_GE_CENPI_214804_at_tn.png
- | GeneAtlas_image2 = PBB_GE_CENPI_207590_s_at_tn.png
- | Function =
- | Component = {{GNF_GO|id=GO:0000775 |text = chromosome, pericentric region}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005694 |text = chromosome}}
- | Process = {{GNF_GO|id=GO:0007283 |text = spermatogenesis}} {{GNF_GO|id=GO:0007292 |text = female gamete generation}} {{GNF_GO|id=GO:0007548 |text = sex differentiation}}
-  | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 2491
-    | Hs_Ensembl = ENSG00000102384
-    | Hs_RefseqProtein = NP_006724
-    | Hs_RefseqmRNA = NM_006733
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = X
-    | Hs_GenLoc_start = 100242082
-    | Hs_GenLoc_end = 100305326
-    | Hs_Uniprot = Q92674
-    | Mm_EntrezGene = 102920
-    | Mm_Ensembl = ENSMUSG00000031262
-    | Mm_RefseqmRNA = XM_975916
-    | Mm_RefseqProtein = XP_981010
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = X
-    | Mm_GenLoc_start = 129654505
-    | Mm_GenLoc_end = 129708989
-    | Mm_Uniprot = Q3TLU9
-  }}
-}}
-'''Centromere protein I''', also known as '''CENPI''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CENPI centromere protein I| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2491| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.<ref name="entrez">{{cite web | title = Entrez Gene: CENPI centromere protein I| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2491| accessdate = }}</ref>
+| summary_text = The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.<ref name="entrez"/>
 }}
 ==References==
-{{reflist|2}}
+{{reflist}}
+==External links==
+* {{UCSC gene info|CENPI}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Izuta H, Ikeno M, Suzuki N, ''et al.'' |title=Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. |journal=Genes Cells |volume=11 |issue= 6 |pages= 673-84 |year= 2006 |pmid= 16716197 |doi= 10.1111/j.1365-2443.2006.00969.x }}
+*{{cite journal  | vauthors=Izuta H, Ikeno M, Suzuki N |title=Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. |journal=Genes Cells |volume=11 |issue= 6 |pages= 673–84 |year= 2006 |pmid= 16716197 |doi= 10.1111/j.1365-2443.2006.00969.x |display-authors=etal}}
-*{{cite journal  | author=Okada M, Cheeseman IM, Hori T, ''et al.'' |title=The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. |journal=Nat. Cell Biol. |volume=8 |issue= 5 |pages= 446-57 |year= 2006 |pmid= 16622420 |doi= 10.1038/ncb1396 }}
+*{{cite journal  | vauthors=Foltz DR, Jansen LE, Black BE |title=The human CENP-A centromeric nucleosome-associated complex. |journal=Nat. Cell Biol. |volume=8 |issue= 5 |pages= 458–69 |year= 2006 |pmid= 16622419 |doi= 10.1038/ncb1397 |display-authors=etal}}
-*{{cite journal  | author=Foltz DR, Jansen LE, Black BE, ''et al.'' |title=The human CENP-A centromeric nucleosome-associated complex. |journal=Nat. Cell Biol. |volume=8 |issue= 5 |pages= 458-69 |year= 2006 |pmid= 16622419 |doi= 10.1038/ncb1397 }}
+*{{cite journal  | vauthors=Nousiainen M, Silljé HH, Sauer G |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103  | pmc=1459365 |display-authors=etal}}
-*{{cite journal  | author=Nousiainen M, Silljé HH, Sauer G, ''et al.'' |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391-6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 }}
+*{{cite journal  | vauthors=Ross MT, Grafham DV, Coffey AJ |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440  | pmc=2665286 |display-authors=etal}}
-*{{cite journal  | author=Ross MT, Grafham DV, Coffey AJ, ''et al.'' |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 }}
+*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | vauthors=Obuse C, Yang H, Nozaki N |title=Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase. |journal=Genes Cells |volume=9 |issue= 2 |pages= 105–20 |year= 2004 |pmid= 15009096 |doi=10.1111/j.1365-2443.2004.00705.x  |display-authors=etal}}
-*{{cite journal  | author=Obuse C, Yang H, Nozaki N, ''et al.'' |title=Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase. |journal=Genes Cells |volume=9 |issue= 2 |pages= 105-20 |year= 2004 |pmid= 15009096 |doi=  }}
+*{{cite journal  | vauthors=Liu ST, Hittle JC, Jablonski SA |title=Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. |journal=Nat. Cell Biol. |volume=5 |issue= 4 |pages= 341–5 |year= 2003 |pmid= 12640463 |doi= 10.1038/ncb953 |display-authors=etal}}
-*{{cite journal  | author=Liu ST, Hittle JC, Jablonski SA, ''et al.'' |title=Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. |journal=Nat. Cell Biol. |volume=5 |issue= 4 |pages= 341-5 |year= 2003 |pmid= 12640463 |doi= 10.1038/ncb953 }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Roberts RG, Kendall E, Vetrie D, Bobrow M |title=Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene. |journal=Genomics |volume=37 |issue= 1 |pages= 122–4 |year= 1997 |pmid= 8921378 |doi= 10.1006/geno.1996.0528 }}
-*{{cite journal  | author=Roberts RG, Kendall E, Vetrie D, Bobrow M |title=Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene. |journal=Genomics |volume=37 |issue= 1 |pages= 122-4 |year= 1997 |pmid= 8921378 |doi= 10.1006/geno.1996.0528 }}
+*{{cite journal  | vauthors=Slegtenhorst-Eegdeman KE, Post M, Baarends WM |title=Regulation of gene expression in Sertoli cells by follicle-stimulating hormone (FSH): cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein. |journal=Mol. Cell. Endocrinol. |volume=108 |issue= 1-2 |pages= 115–24 |year= 1995 |pmid= 7758824 |doi=10.1016/0303-7207(94)03468-9  |display-authors=etal}}
-*{{cite journal  | author=Slegtenhorst-Eegdeman KE, Post M, Baarends WM, ''et al.'' |title=Regulation of gene expression in Sertoli cells by follicle-stimulating hormone (FSH): cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein. |journal=Mol. Cell. Endocrinol. |volume=108 |issue= 1-2 |pages= 115-24 |year= 1995 |pmid= 7758824 |doi=  }}
+*{{cite journal  | vauthors=Adams MD, Dubnick M, Kerlavage AR |title=Sequence identification of 2,375 human brain genes. |journal=Nature |volume=355 |issue= 6361 |pages= 632–4 |year= 1992 |pmid= 1538749 |doi= 10.1038/355632a0 |display-authors=etal}}
-*{{cite journal  | author=Adams MD, Dubnick M, Kerlavage AR, ''et al.'' |title=Sequence identification of 2,375 human brain genes. |journal=Nature |volume=355 |issue= 6361 |pages= 632-4 |year= 1992 |pmid= 1538749 |doi= 10.1038/355632a0 }}
 }}
 {{refend}}
-{{protein-stub}}
 {{Chromosome genetics}}
-{{WikiDoc Sources}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+{{gene-X-stub}}

CENPI: Difference between revisions

Revision as of 09:33, 30 August 2017

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