Ascending cholangitis history and symptoms: Difference between revisions

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==Overview==
==Overview==
he majority of patients with [disease name] are asymptomatic.
Ascending Cholangitis, also known as acute cholangitis is a systemic disease caused by the inflammation and infection of the biliary tree most commonly following an obstruction in the biliary tract. It is characterized by a triad (Charcot's Triad) of fever, jaundice and right upper quadrant pain. A pentad (also known as Reynold's pentad) can also be seen in which altered mental status and sepsis are present in addition to usual findings
 
OR
 
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


==History and Symptoms==
==History and Symptoms==
The following symptoms may occur:
The following symptoms may occur:
*Abdominal pain which is in the right upper side or middle of the upper abdomen and may come and go. Pain is sharp, crampy, or dull and may move to the back or below the right shoulder blade.
*Abdominal pain which is in the right upper quadrant and is intermittent. Pain is sharp, crampy, or dull and may move to the back or below the right shoulder blade.
*Yellowing of the skin (jaundice) - 6- to 70 percent patients
*Fever - seen in 90 percent of patients
*Chills
*Chills
*Fever
*Clay-colored stools
*Clay-colored stools
*Dark urine
*Dark urine
*Nausea and vomiting
*Nausea and vomiting
*Yellowing of the skin (jaundice) -- may come and go
*Pruritis
*The clinical symptoms of ascending cholangitis are pain, [[jaundice]], and fever ('''[[Charcot's triad]]'''). In addition, the presence of hypotension and mental confusion ('''Reynold's pentad''') is suggestive of severe [[septicemia]].
*Fatigue
 
*The clinical triad of ascending cholangitis are pain, [[jaundice]], and fever ('''[[Charcot's triad]]'''). In addition, the presence of hypotension and mental confusion ('''Reynold's pentad''') is suggestive of severe [[septicemia]].
The typical clinical picture is present in only 50% of cases.
* The majority of patients with [disease name] are asymptomatic.
OR
* The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
* Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].  


The typical clinical picture with a triad is present in only 50 to 70 percent of cases<ref name="pmid1098507">{{cite journal| author=Saik RP, Greenburg AG, Farris JM, Peskin GW| title=Spectrum of cholangitis. | journal=Am J Surg | year= 1975 | volume= 130 | issue= 2 | pages= 143-50 | pmid=1098507 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1098507  }}</ref>.
=== History ===
=== History ===
Patients with [disease name]] may have a positive history of:
Patients with ascending cholangitis may have a positive history of:
* [History finding 1]
* Gallstones
* [History finding 2]
* Common bile duct stones
* [History finding 3]
* Cholecystectomy
 
* Cholangiogram
=== Common Symptoms ===
* ERCP
Common symptoms of [disease] include:
* Previous history of cholangitis
* [Symptom 1]
* HIV or AIDS<ref name="pmid21994858">{{cite journal| author=Gao Y, Chin K, Mishriki YY| title=AIDS Cholangiopathy in an Asymptomatic, Previously Undiagnosed Late-Stage HIV-Positive Patient from Kenya. | journal=Int J Hepatol | year= 2011 | volume= 2011 | issue= | pages= 465895 | pmid=21994858 | doi=10.4061/2011/465895 | pmc=3170813 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21994858  }}</ref> - [[AIDS]]-related cholangitis is characterized by extrahepatic biliary [[edema]], [[ulceration]], and obstruction
* [Symptom 2]
* [Symptom 3]
 
=== Less Common Symptoms ===
Less common symptoms of [disease name] include
* [Symptom 1]
* [Symptom 2]
* [Symptom 3]


==References==
==References==

Revision as of 14:42, 28 September 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Ascending Cholangitis, also known as acute cholangitis is a systemic disease caused by the inflammation and infection of the biliary tree most commonly following an obstruction in the biliary tract. It is characterized by a triad (Charcot's Triad) of fever, jaundice and right upper quadrant pain. A pentad (also known as Reynold's pentad) can also be seen in which altered mental status and sepsis are present in addition to usual findings

History and Symptoms

The following symptoms may occur:

  • Abdominal pain which is in the right upper quadrant and is intermittent. Pain is sharp, crampy, or dull and may move to the back or below the right shoulder blade.
  • Yellowing of the skin (jaundice) - 6- to 70 percent patients
  • Fever - seen in 90 percent of patients
  • Chills
  • Clay-colored stools
  • Dark urine
  • Nausea and vomiting
  • Pruritis
  • Fatigue
  • The clinical triad of ascending cholangitis are pain, jaundice, and fever (Charcot's triad). In addition, the presence of hypotension and mental confusion (Reynold's pentad) is suggestive of severe septicemia.

The typical clinical picture with a triad is present in only 50 to 70 percent of cases[1].

History

Patients with ascending cholangitis may have a positive history of:

  • Gallstones
  • Common bile duct stones
  • Cholecystectomy
  • Cholangiogram
  • ERCP
  • Previous history of cholangitis
  • HIV or AIDS[2] - AIDS-related cholangitis is characterized by extrahepatic biliary edema, ulceration, and obstruction

References

  1. Saik RP, Greenburg AG, Farris JM, Peskin GW (1975). "Spectrum of cholangitis". Am J Surg. 130 (2): 143–50. PMID 1098507.
  2. Gao Y, Chin K, Mishriki YY (2011). "AIDS Cholangiopathy in an Asymptomatic, Previously Undiagnosed Late-Stage HIV-Positive Patient from Kenya". Int J Hepatol. 2011: 465895. doi:10.4061/2011/465895. PMC 3170813. PMID 21994858.

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