Sjögren's syndrome history and symptoms: Difference between revisions

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===Common Symptoms===
===Common Symptoms===
Common symptoms of Sjögren's syndrome include:<ref name="pmid21291650">{{cite journal |vauthors=Kittridge A, Routhouska SB, Korman NJ |title=Dermatologic manifestations of Sjögren syndrome |journal=J Cutan Med Surg |volume=15 |issue=1 |pages=8–14 |date=2011 |pmid=21291650 |doi=10.2310/7750.2010.09033 |url=}}</ref><ref name="pmid15485020">{{cite journal |vauthors=Roguedas AM, Misery L, Sassolas B, Le Masson G, Pennec YL, Youinou P |title=Cutaneous manifestations of primary Sjögren's syndrome are underestimated |journal=Clin. Exp. Rheumatol. |volume=22 |issue=5 |pages=632–6 |date=2004 |pmid=15485020 |doi= |url=}}</ref><ref name="pmid19745687">{{cite journal |vauthors=Baimpa E, Dahabreh IJ, Voulgarelis M, Moutsopoulos HM |title=Hematologic manifestations and predictors of lymphoma development in primary Sjögren syndrome: clinical and pathophysiologic aspects |journal=Medicine (Baltimore) |volume=88 |issue=5 |pages=284–93 |date=September 2009 |pmid=19745687 |doi=10.1097/MD.0b013e3181b76ab5 |url=}}</ref><ref name="pmid16284097">{{cite journal |vauthors=Theander E, Henriksson G, Ljungberg O, Mandl T, Manthorpe R, Jacobsson LT |title=Lymphoma and other malignancies in primary Sjögren's syndrome: a cohort study on cancer incidence and lymphoma predictors |journal=Ann. Rheum. Dis. |volume=65 |issue=6 |pages=796–803 |date=June 2006 |pmid=16284097 |pmc=1798187 |doi=10.1136/ard.2005.041186 |url=}}</ref><ref name="pmid21291650">{{cite journal |vauthors=Kittridge A, Routhouska SB, Korman NJ |title=Dermatologic manifestations of Sjögren syndrome |journal=J Cutan Med Surg |volume=15 |issue=1 |pages=8–14 |date=2011 |pmid=21291650 |doi=10.2310/7750.2010.09033 |url=}}</ref><ref name="pmid23936829">{{cite journal |vauthors=Amezcua-Guerra LM, Hofmann F, Vargas A, Rodriguez-Henriquez P, Solano C, Hernández-Díaz C, Castillo-Martinez D, Ventura-Ríos L, Gutiérrez M, Pineda C |title=Joint involvement in primary Sjögren's syndrome: an ultrasound "target area approach to arthritis" |journal=Biomed Res Int |volume=2013 |issue= |pages=640265 |date=2013 |pmid=23936829 |pmc=3722787 |doi=10.1155/2013/640265 |url=}}</ref><ref name="pmid11961175">{{cite journal |vauthors=Kanellopoulos P, Baltoyiannis C, Tzioufas AG |title=Primary Sjögren's syndrome associated with inclusion body myositis |journal=Rheumatology (Oxford) |volume=41 |issue=4 |pages=440–4 |date=April 2002 |pmid=11961175 |doi= |url=}}</ref><ref name="pmid7485204">{{cite journal |vauthors=Pérez B, Kraus A, López G, Cifuentes M, Alarcón-Segovia D |title=Autoimmune thyroid disease in primary Sjögren's syndrome |journal=Am. J. Med. |volume=99 |issue=5 |pages=480–4 |date=November 1995 |pmid=7485204 |doi= |url=}}</ref><ref name="pmid1271390">{{cite journal |vauthors=Ramirez-Mata M, Pena Ancira FF, Alarcon-Segovia D |title=Abnormal esophageal motility in primary Sjögren's syndrome |journal=J. Rheumatol. |volume=3 |issue=1 |pages=63–9 |date=March 1976 |pmid=1271390 |doi= |url=}}</ref><ref name="pmid8141212">{{cite journal |vauthors=Lehrer S, Bogursky E, Yemini M, Kase NG, Birkenfeld A |title=Gynecologic manifestations of Sjögren's syndrome |journal=Am. J. Obstet. Gynecol. |volume=170 |issue=3 |pages=835–7 |date=March 1994 |pmid=8141212 |doi= |url=}}</ref><ref name="pmid3261608">{{cite journal |vauthors=Binder A, Snaith ML, Isenberg D |title=Sjögren's syndrome: a study of its neurological complications |journal=Br. J. Rheumatol. |volume=27 |issue=4 |pages=275–80 |date=August 1988 |pmid=3261608 |doi= |url=}}</ref><ref name="pmid12169883">{{cite journal |vauthors=Ramos-Casals M, Font J, Garcia-Carrasco M, Brito MP, Rosas J, Calvo-Alen J, Pallares L, Cervera R, Ingelmo M |title=Primary Sjögren syndrome: hematologic patterns of disease expression |journal=Medicine (Baltimore) |volume=81 |issue=4 |pages=281–92 |date=July 2002 |pmid=12169883 |doi= |url=}}</ref>
Common symptoms of Sjögren's syndrome include:<ref name="pmid21291650">{{cite journal |vauthors=Kittridge A, Routhouska SB, Korman NJ |title=Dermatologic manifestations of Sjögren syndrome |journal=J Cutan Med Surg |volume=15 |issue=1 |pages=8–14 |date=2011 |pmid=21291650 |doi=10.2310/7750.2010.09033 |url=}}</ref><ref name="pmid15485020">{{cite journal |vauthors=Roguedas AM, Misery L, Sassolas B, Le Masson G, Pennec YL, Youinou P |title=Cutaneous manifestations of primary Sjögren's syndrome are underestimated |journal=Clin. Exp. Rheumatol. |volume=22 |issue=5 |pages=632–6 |date=2004 |pmid=15485020 |doi= |url=}}</ref><ref name="pmid19745687">{{cite journal |vauthors=Baimpa E, Dahabreh IJ, Voulgarelis M, Moutsopoulos HM |title=Hematologic manifestations and predictors of lymphoma development in primary Sjögren syndrome: clinical and pathophysiologic aspects |journal=Medicine (Baltimore) |volume=88 |issue=5 |pages=284–93 |date=September 2009 |pmid=19745687 |doi=10.1097/MD.0b013e3181b76ab5 |url=}}</ref><ref name="pmid21291650">{{cite journal |vauthors=Kittridge A, Routhouska SB, Korman NJ |title=Dermatologic manifestations of Sjögren syndrome |journal=J Cutan Med Surg |volume=15 |issue=1 |pages=8–14 |date=2011 |pmid=21291650 |doi=10.2310/7750.2010.09033 |url=}}</ref><ref name="pmid23936829">{{cite journal |vauthors=Amezcua-Guerra LM, Hofmann F, Vargas A, Rodriguez-Henriquez P, Solano C, Hernández-Díaz C, Castillo-Martinez D, Ventura-Ríos L, Gutiérrez M, Pineda C |title=Joint involvement in primary Sjögren's syndrome: an ultrasound "target area approach to arthritis" |journal=Biomed Res Int |volume=2013 |issue= |pages=640265 |date=2013 |pmid=23936829 |pmc=3722787 |doi=10.1155/2013/640265 |url=}}</ref><ref name="pmid11961175">{{cite journal |vauthors=Kanellopoulos P, Baltoyiannis C, Tzioufas AG |title=Primary Sjögren's syndrome associated with inclusion body myositis |journal=Rheumatology (Oxford) |volume=41 |issue=4 |pages=440–4 |date=April 2002 |pmid=11961175 |doi= |url=}}</ref><ref name="pmid7485204">{{cite journal |vauthors=Pérez B, Kraus A, López G, Cifuentes M, Alarcón-Segovia D |title=Autoimmune thyroid disease in primary Sjögren's syndrome |journal=Am. J. Med. |volume=99 |issue=5 |pages=480–4 |date=November 1995 |pmid=7485204 |doi= |url=}}</ref><ref name="pmid1271390">{{cite journal |vauthors=Ramirez-Mata M, Pena Ancira FF, Alarcon-Segovia D |title=Abnormal esophageal motility in primary Sjögren's syndrome |journal=J. Rheumatol. |volume=3 |issue=1 |pages=63–9 |date=March 1976 |pmid=1271390 |doi= |url=}}</ref><ref name="pmid8141212">{{cite journal |vauthors=Lehrer S, Bogursky E, Yemini M, Kase NG, Birkenfeld A |title=Gynecologic manifestations of Sjögren's syndrome |journal=Am. J. Obstet. Gynecol. |volume=170 |issue=3 |pages=835–7 |date=March 1994 |pmid=8141212 |doi= |url=}}</ref><ref name="pmid3261608">{{cite journal |vauthors=Binder A, Snaith ML, Isenberg D |title=Sjögren's syndrome: a study of its neurological complications |journal=Br. J. Rheumatol. |volume=27 |issue=4 |pages=275–80 |date=August 1988 |pmid=3261608 |doi= |url=}}</ref><ref name="pmid12169883">{{cite journal |vauthors=Ramos-Casals M, Font J, Garcia-Carrasco M, Brito MP, Rosas J, Calvo-Alen J, Pallares L, Cervera R, Ingelmo M |title=Primary Sjögren syndrome: hematologic patterns of disease expression |journal=Medicine (Baltimore) |volume=81 |issue=4 |pages=281–92 |date=July 2002 |pmid=12169883 |doi= |url=}}</ref>
*'''Skin manifestations'''
*'''Skin manifestations'''
**Xerosis  
**Xerosis  

Revision as of 18:51, 9 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]


Overview

History and Symptoms

  • The most common symptoms of Sjögren's syndrome include ocular and oral symptoms.

History

Patients with Sjögren's syndrome may have a positive history of:

  • Rheumatoid arthritis (RA)
  • Systemic lupus erythematous (SLE)
  • Non-Hodgkin B-cell lymphoma

Common Symptoms

Common symptoms of Sjögren's syndrome include:[1][2][3][1][4][5][6][7][8][9][10]

  • Skin manifestations
    • Xerosis
    • Purpura, associated with vascular or hematologic abnormalities
    • Raynaud phenomenon
    • Cutaneous vasculitis
    • Annular erythema
    • Erythema nodosum
    • Livedo reticularis
    • Lichen planus
    • Vitiligo
    • Cutaneous amyloidosis
    • Granuloma annulare
    • Angular cheilitis
    • Eyelid dermatitis
  • Musculoskeletal manifestations
    • Arthralgia
    • Arthritis
    • Myopathy
  • Fatigue and fibromyalgia
  • Pulmonary symptoms
    • Dryness of the tracheobronchial mucosa(xerotrachea)
    • Dry cough
    • Recurrent bronchitis
    • Pneumonitis (infectious or noninfectious)
  • Gastrointestinal manifestations
    • Dysphagia
    • Nausea
    • Dyspepsia and gastritis
    • Celiac disease
    • Hepatic abnormalities
    • subclinical pancreatic disease
    • Dyspnea from interstitial lung disease
  • Cardiac involvement
    • Pericarditis
    • Pulmonary hypertension
    • Dysfunction of autonomic control of blood pressure
    • Myocardial disease
  • Neurologic and psychiatric symptoms
    • Myelopathy
    • Optic neuropathy
    • Seizures
    • Cognitive dysfunction
    • Encephalopathy
    • Painful sensory neuropathy
    • Sensory ataxic neuropathy
    • Pure sensory trigeminal neuropathy
    • Axonal sensorimotor polyneuropathy
    • Mononeuritis multiplex
    • Multiple cranial neuropathies
    • Radiculoneuropathy
    • Autonomic neuropathy
    • Depression
  • Urogenital manifestations
    • Interstitial nephritis
    • Interstitial cystitis
    • Vulvovaginal dryness, pruritus, and dyspareunia
  • Parotitis
  • Cutaneous vasculitis

References

  1. ↑ 1.0 1.1 Kittridge A, Routhouska SB, Korman NJ (2011). "Dermatologic manifestations of Sjögren syndrome". J Cutan Med Surg. 15 (1): 8–14. doi:10.2310/7750.2010.09033. PMID 21291650.
  2. ↑ Roguedas AM, Misery L, Sassolas B, Le Masson G, Pennec YL, Youinou P (2004). "Cutaneous manifestations of primary Sjögren's syndrome are underestimated". Clin. Exp. Rheumatol. 22 (5): 632–6. PMID 15485020.
  3. ↑ Baimpa E, Dahabreh IJ, Voulgarelis M, Moutsopoulos HM (September 2009). "Hematologic manifestations and predictors of lymphoma development in primary Sjögren syndrome: clinical and pathophysiologic aspects". Medicine (Baltimore). 88 (5): 284–93. doi:10.1097/MD.0b013e3181b76ab5. PMID 19745687.
  4. ↑ Amezcua-Guerra LM, Hofmann F, Vargas A, Rodriguez-Henriquez P, Solano C, Hernández-Díaz C, Castillo-Martinez D, Ventura-Ríos L, Gutiérrez M, Pineda C (2013). "Joint involvement in primary Sjögren's syndrome: an ultrasound "target area approach to arthritis"". Biomed Res Int. 2013: 640265. doi:10.1155/2013/640265. PMC 3722787. PMID 23936829.
  5. ↑ Kanellopoulos P, Baltoyiannis C, Tzioufas AG (April 2002). "Primary Sjögren's syndrome associated with inclusion body myositis". Rheumatology (Oxford). 41 (4): 440–4. PMID 11961175.
  6. ↑ Pérez B, Kraus A, López G, Cifuentes M, Alarcón-Segovia D (November 1995). "Autoimmune thyroid disease in primary Sjögren's syndrome". Am. J. Med. 99 (5): 480–4. PMID 7485204.
  7. ↑ Ramirez-Mata M, Pena Ancira FF, Alarcon-Segovia D (March 1976). "Abnormal esophageal motility in primary Sjögren's syndrome". J. Rheumatol. 3 (1): 63–9. PMID 1271390.
  8. ↑ Lehrer S, Bogursky E, Yemini M, Kase NG, Birkenfeld A (March 1994). "Gynecologic manifestations of Sjögren's syndrome". Am. J. Obstet. Gynecol. 170 (3): 835–7. PMID 8141212.
  9. ↑ Binder A, Snaith ML, Isenberg D (August 1988). "Sjögren's syndrome: a study of its neurological complications". Br. J. Rheumatol. 27 (4): 275–80. PMID 3261608.
  10. ↑ Ramos-Casals M, Font J, Garcia-Carrasco M, Brito MP, Rosas J, Calvo-Alen J, Pallares L, Cervera R, Ingelmo M (July 2002). "Primary Sjögren syndrome: hematologic patterns of disease expression". Medicine (Baltimore). 81 (4): 281–92. PMID 12169883.

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