Multi-drug-resistant tuberculosis classification: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 6: Line 6:
Based on the drug susceptibility testing of cinical isolates confirmed to be Mycobacterium tuberculosis,
Based on the drug susceptibility testing of cinical isolates confirmed to be Mycobacterium tuberculosis,
The strains are classified as follows. <ref name=WHO>{{cite web | title =Drug resistance Classification| url =http://apps.who.int/iris/bitstream/10665/79199/1/9789241505345_eng.pdf }}</ref>
The strains are classified as follows. <ref name=WHO>{{cite web | title =Drug resistance Classification| url =http://apps.who.int/iris/bitstream/10665/79199/1/9789241505345_eng.pdf }}</ref>
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
|valign=top|
|+
! style="background: #4479BA; width: 250px;" | {{fontcolor|#FFF|Classification}}
! style="background: #4479BA; width: 350px;" | {{fontcolor|#FFF|Description}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Monoresistance
| style="padding: 5px 5px; background: #F5F5F5;" |Strain resistant to any one of the first line anti tubercular drugs
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Polydrug resistance
| style="padding: 5px 5px; background: #F5F5F5;" |Strain resistant to more than one first line anti tubercular drugs. (Other than both rifampicin and isoniazid)
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Multidrug resistance
| style="padding: 5px 5px; background: #F5F5F5;" |Strain resistant to both rifampicin and isoniazid
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Extensive drug resistance
| style="padding: 5px 5px; background: #F5F5F5;" |In addition to the multi drug resistance, strain is resistant to any fluroquinolone and to atleast one of the three second line anti injectable drugs like amikacin, capreomycin and kanamycin.
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Rifampicin resistance
| style="padding: 5px 5px; background: #F5F5F5;" | Using genotypic or phenotypic method, strain has been detected to have resistance to rifampicin with or without resistance to other anti TB drugs. It can include monoresistance, multi drug resistance, poly drug resistance or extensive drug resistance.
|}





Revision as of 15:54, 26 September 2014

Multi-drug-resistant tuberculosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Multi-drug-resistant tuberculosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Multi-drug-resistant tuberculosis classification On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Multi-drug-resistant tuberculosis classification

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Multi-drug-resistant tuberculosis classification

CDC on Multi-drug-resistant tuberculosis classification

Multi-drug-resistant tuberculosis classification in the news

Blogs on Multi-drug-resistant tuberculosis classification

Directions to Hospitals Treating Multi-drug-resistant tuberculosis

Risk calculators and risk factors for Multi-drug-resistant tuberculosis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Classification

Based on the drug susceptibility testing of cinical isolates confirmed to be Mycobacterium tuberculosis, The strains are classified as follows. [1]

Classification Description
Monoresistance Strain resistant to any one of the first line anti tubercular drugs
Polydrug resistance Strain resistant to more than one first line anti tubercular drugs. (Other than both rifampicin and isoniazid)
Multidrug resistance Strain resistant to both rifampicin and isoniazid
Extensive drug resistance In addition to the multi drug resistance, strain is resistant to any fluroquinolone and to atleast one of the three second line anti injectable drugs like amikacin, capreomycin and kanamycin.
Rifampicin resistance Using genotypic or phenotypic method, strain has been detected to have resistance to rifampicin with or without resistance to other anti TB drugs. It can include monoresistance, multi drug resistance, poly drug resistance or extensive drug resistance.


References

  1. "Drug resistance Classification" (PDF).

Template:WH Template:WS