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==Overview==
==Overview==
In the medical field, leishmaniasis is one of the famous causes of a markedly enlarged spleen, which may become larger even than the liver. There are four main forms of leishmaniasis:
Leishmaniasis is classified according to the clinical manifestation. The most common forms are cutaneous leishmaniasis, which causes skin sores, and visceral leishmaniasis, which affects several internal organs (usually spleen, liver, and bone marrow).  Mucosal leishmaniasis is a form of the disease that affects the mucous membranes of the mouth, nose and throat.
*[[Visceral leishmaniasis]] - the most serious form and potentially fatal if untreated.
 
*[[Cutaneous leishmaniasis]] - the most common form which causes a sore at the bite site, which heal in a few months to a year, leaving an unpleasant looking scar. This form can progress to any of the other three forms.
==Classification==
*Diffuse cutaneous leishmaniasis - this form produces widespread skin lesions which resemble leprosy and is particularly difficult to treat.
Leishmaniasis is classified in 3 different presentation forms: cutaneous, mucosal, and visceral leishmaniasis. <ref> {{cite web|url=http://www.cdc.gov/parasites/leishmaniasis/disease.html| title=CDC Parasites Leishmaniasis- Disease}}</ref>
*Mucocutaneous leishmaniasis - commences with skin ulcers which spread causing tissue damage to (particularly) nose and mouth
===Cutaneous Leishmaniasis===
* The most common form is cutaneous leishmaniasis, which causes skin lesions.
*The lesions typically develop within a few weeks or months of the sand fly bite.
*These lesions can change in size and appearance over time.
*They may start out as [[papules]] (bumps) or [[nodules]] (lumps) and may end up as [[ulcers]]; [[skin ulcer]]s might be covered by scab or crust.
*The sores usually are painless but can be painful.
* Some people have swollen glands near the sores.
 
===Mucosal Leishmaniasis===
*Mucosal or mucocutaneous leishmaniasis is an example of one of the less common forms of leishmaniasis.
*This form can be a [[sequela]] of infection with some of the species (types) of the parasite that cause cutaneous leishmaniasis in parts of Latin America.
* Certain types of the parasite might spread from the skin and cause sores in the mucous membranes of the [[nose]] (most common location), [[mouth]], or throat.
 
===Visceral Leishmaniasis===
Visceral leishmaniasis affects several internal organs (usually [[spleen]], [[liver]], and [[bone marrow]]) and can be life threatening.
*The illness typically develops within months (sometimes as long as years) of the sand fly bite.  
*Affected people usually have [[fever]], [[weight loss]], [[hepatosplenomegaly]], and low blood counts ([[anemia]], [[leukopenia]], and [[thrombocytopenia]]).


==References==
==References==
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Infectious disease]]


[[Category:Zoonoses]]
[[Category:Parasitic diseases]]
[[Category:Parasitic diseases]]
[[Category:Tropical disease]]
[[Category:Tropical disease]]

Latest revision as of 18:09, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Leishmaniasis is classified according to the clinical manifestation. The most common forms are cutaneous leishmaniasis, which causes skin sores, and visceral leishmaniasis, which affects several internal organs (usually spleen, liver, and bone marrow). Mucosal leishmaniasis is a form of the disease that affects the mucous membranes of the mouth, nose and throat.

Classification

Leishmaniasis is classified in 3 different presentation forms: cutaneous, mucosal, and visceral leishmaniasis. [1]

Cutaneous Leishmaniasis

  • The most common form is cutaneous leishmaniasis, which causes skin lesions.
  • The lesions typically develop within a few weeks or months of the sand fly bite.
  • These lesions can change in size and appearance over time.
  • They may start out as papules (bumps) or nodules (lumps) and may end up as ulcers; skin ulcers might be covered by scab or crust.
  • The sores usually are painless but can be painful.
  • Some people have swollen glands near the sores.

Mucosal Leishmaniasis

  • Mucosal or mucocutaneous leishmaniasis is an example of one of the less common forms of leishmaniasis.
  • This form can be a sequela of infection with some of the species (types) of the parasite that cause cutaneous leishmaniasis in parts of Latin America.
  • Certain types of the parasite might spread from the skin and cause sores in the mucous membranes of the nose (most common location), mouth, or throat.

Visceral Leishmaniasis

Visceral leishmaniasis affects several internal organs (usually spleen, liver, and bone marrow) and can be life threatening.

References

  1. "CDC Parasites Leishmaniasis- Disease".


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