Intussusception causes: Difference between revisions

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==Overview==
==Overview==
Common causes of Intussusception in children can be idiopathic and pathologic. Idiopathic causes include seasonal [[viral gastroenteritis]], [[Rotavirus vaccine (patient information)|rotavirus vaccine]], [[adenovirus infection]], and [[bacterial enteritis]]. Pathologic causes of intussusception in children include [https://www.wikidoc.org/index.php/Henoch-Schönlein_purpura henoch-schonlein purpura], [[cystic fibrosis]], [[celiac disease]], [[crohn's disease]], [[meckel's diverticulum]], [[Polyp|polyps]], duplication cysts, and [[lymphoma]]. Intussusception is adults is mostly due to a pathologic lead point. Non-idiopathic adult intestinal causes for intussusception can further be divided into [[benign]] and [[malignant]] enteric causes, and [[benign]] and [[malignant]] colonic causes.  
Common causes of intussusception in children can be divided into idiopathic and pathologic. Idiopathic causes include seasonal [[viral gastroenteritis]], [[Rotavirus vaccine (patient information)|rotavirus vaccine]], [[adenovirus infection]], and [[bacterial enteritis]]. Pathologic causes of intussusception in children include [[Henoch-Schönlein purpura|Henoch-Schonlein purpura]], [[cystic fibrosis]], [[Celiac disease]], [[Crohn's disease]], [[Meckel's diverticulum]], [[Polyp|polyps]], duplication cysts, and [[lymphoma]]. Intussusception in adults is mostly due to a pathologic lead point. Non-idiopathic intestinal causes for intussusception in adults can further be divided into [[benign]] and [[malignant]] [[enteric]] causes, and [[benign]] and [[malignant]] [[Colon|colonic]] causes.  


==Causes==
==Causes==
* Causes in children
* Causes in children
** Idiopathic:
** Idiopathic:
*** Seasonal viral gastroenteritis<ref name="pmid17766518">{{cite journal |vauthors=Buettcher M, Baer G, Bonhoeffer J, Schaad UB, Heininger U |title=Three-year surveillance of intussusception in children in Switzerland |journal=Pediatrics |volume=120 |issue=3 |pages=473–80 |year=2007 |pmid=17766518 |doi=10.1542/peds.2007-0035 |url=}}</ref>
*** Seasonal [[viral gastroenteritis]]<ref name="pmid17766518">{{cite journal |vauthors=Buettcher M, Baer G, Bonhoeffer J, Schaad UB, Heininger U |title=Three-year surveillance of intussusception in children in Switzerland |journal=Pediatrics |volume=120 |issue=3 |pages=473–80 |year=2007 |pmid=17766518 |doi=10.1542/peds.2007-0035 |url=}}</ref>
*** [[Rotavirus vaccine (patient information)|Rotavirus vaccine]] <ref name="pmid26209838">{{cite journal |vauthors=Shimabukuro TT, Nguyen M, Martin D, DeStefano F |title=Safety monitoring in the Vaccine Adverse Event Reporting System (VAERS) |journal=Vaccine |volume=33 |issue=36 |pages=4398–405 |year=2015 |pmid=26209838 |pmc=4632204 |doi=10.1016/j.vaccine.2015.07.035 |url=}}</ref>
*** [[Rotavirus vaccine (patient information)|Rotavirus vaccine]] <ref name="pmid26209838">{{cite journal |vauthors=Shimabukuro TT, Nguyen M, Martin D, DeStefano F |title=Safety monitoring in the Vaccine Adverse Event Reporting System (VAERS) |journal=Vaccine |volume=33 |issue=36 |pages=4398–405 |year=2015 |pmid=26209838 |pmc=4632204 |doi=10.1016/j.vaccine.2015.07.035 |url=}}</ref>
*** [[Adenovirus infection|Adenovirus]] <ref name="pmid17011313">{{cite journal |vauthors=Bines JE, Liem NT, Justice FA, Son TN, Kirkwood CD, de Campo M, Barnett P, Bishop RF, Robins-Browne R, Carlin JB |title=Risk factors for intussusception in infants in Vietnam and Australia: adenovirus implicated, but not rotavirus |journal=J. Pediatr. |volume=149 |issue=4 |pages=452–60 |year=2006 |pmid=17011313 |doi=10.1016/j.jpeds.2006.04.010 |url=}}</ref>
*** [[Adenovirus infection|Adenovirus]] <ref name="pmid17011313">{{cite journal |vauthors=Bines JE, Liem NT, Justice FA, Son TN, Kirkwood CD, de Campo M, Barnett P, Bishop RF, Robins-Browne R, Carlin JB |title=Risk factors for intussusception in infants in Vietnam and Australia: adenovirus implicated, but not rotavirus |journal=J. Pediatr. |volume=149 |issue=4 |pages=452–60 |year=2006 |pmid=17011313 |doi=10.1016/j.jpeds.2006.04.010 |url=}}</ref>
*** Bacterial enteritis
*** [[Bacterial]] enteritis
** Pathologic
** Pathologic
*** [[Henoch-Schönlein purpura]] <ref name="pmid18351468">{{cite journal |vauthors=Ebert EC |title=Gastrointestinal manifestations of Henoch-Schonlein Purpura |journal=Dig. Dis. Sci. |volume=53 |issue=8 |pages=2011–9 |year=2008 |pmid=18351468 |doi=10.1007/s10620-007-0147-0 |url=}}</ref>
*** [[Henoch-Schönlein purpura]] <ref name="pmid18351468">{{cite journal |vauthors=Ebert EC |title=Gastrointestinal manifestations of Henoch-Schonlein Purpura |journal=Dig. Dis. Sci. |volume=53 |issue=8 |pages=2011–9 |year=2008 |pmid=18351468 |doi=10.1007/s10620-007-0147-0 |url=}}</ref>
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{| class="wikitable sortable"
{| class="wikitable sortable"
! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" + ||<big>Causes of nonidiopathic adult intestinal intussusception*</big>
! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" + |<big>Causes of nonidiopathic adult intestinal intussusception*</big>
|-
|-
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Enteric (benign)
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Enteric (benign)
Line 38: Line 38:
! align="center" style="background:#4479BA; color: #FFFFFF;" + |'''Colonic (malignant)'''
! align="center" style="background:#4479BA; color: #FFFFFF;" + |'''Colonic (malignant)'''
|-
|-
|Adhesions
|
 
* Adhesions
Adenoma
* [[Adenoma]]
 
* [[Celiac disease]]
Celiac disease
* [[Crohn's disease]]
 
* [[Endometriosis]]
Crohn disease
* Malignant stromal ([[Gastrointestinal stromal tumor|GIST]]) tumor
 
* [[Hamartoma]]
Endometriosis
* [[Hemangioma]]
 
* Inflammatory polyp
Malignant stromal (GIST) tumor
* [[Kaposi's sarcoma]]
 
* [[Lipoma]]
Hamartoma
* [[Meckel's diverticulum]]
 
* [[Neurofibroma]]
Hemangioma
* [[Peutz–Jeghers syndrome|Peutz–Jegher polyp]]
 
* [[Tuberculosis]]
Inflammatory polyp
* [[Submucosal]] [[hemorrhages]] from unregulated [[anticoagulation]]
 
|
Kaposi sarcoma
* [[Adenocarcinoma]]
 
* [[Carcinoid tumor]]
Lipoma
* [[Leiomyosarcoma]]
 
* [[Lymphoma]]
Meckel diverticulum
* [[Metastatic carcinomas|Metastatic carcinoma]] ([[melanoma]] most common)
 
* [[Malignant]] [[Gastrointestinal stromal tumor|GIST]]
Neurofibroma
* [[Neuroendocrine tumors|Neuroendocrine tumor]]
 
|
Peutz–Jegher polyp
* [[Adenoma]]
 
* Inflammatory pseudopolyp
Tuberculosis
* [[Lipoma]]
 
|
Submucosal hemorrhages from unregulated anticoagulation
* [[Adenocarcinoma]]
|Adenocarcinoma
* [[Lymphoma]]
Carcinoid tumor
* [[Sarcoma]]
 
Leiomyosarcoma
 
Lymphoma
 
Metastatic carcinoma (melanoma most common)
 
Malignant GIST
 
Neuroendocrine tumor
| Adenoma
 
 Inflammatory pseudopolyp
 
 Lipoma
|Adenocarcinoma
 
Lymphoma
 
Sarcoma
|}
|}
<nowiki>*</nowiki>adopted from Clinics in Colon and Rectal Surgery 2017;<ref name="urlThieme E-Journals - Clinics in Colon and Rectal Surgery / Abstract">{{cite web |url=http://dx.doi.org/+10.1055/s-0036-1593429 |title=Thieme E-Journals - Clinics in Colon and Rectal Surgery / Abstract |format= |work= |accessdate=}}</ref>
<nowiki>*</nowiki>Adopted from Clinics in Colon and Rectal Surgery 2017<ref name="urlThieme E-Journals - Clinics in Colon and Rectal Surgery / Abstract">{{cite web |url=http://dx.doi.org/+10.1055/s-0036-1593429 |title=Thieme E-Journals - Clinics in Colon and Rectal Surgery / Abstract |format= |work= |accessdate=}}</ref>


==References==
==References==

Latest revision as of 04:21, 8 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[2]

Overview

Common causes of intussusception in children can be divided into idiopathic and pathologic. Idiopathic causes include seasonal viral gastroenteritis, rotavirus vaccine, adenovirus infection, and bacterial enteritis. Pathologic causes of intussusception in children include Henoch-Schonlein purpura, cystic fibrosis, Celiac disease, Crohn's disease, Meckel's diverticulum, polyps, duplication cysts, and lymphoma. Intussusception in adults is mostly due to a pathologic lead point. Non-idiopathic intestinal causes for intussusception in adults can further be divided into benign and malignant enteric causes, and benign and malignant colonic causes.

Causes


 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Children
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Idiopathic- no lead point
 
 
 
Pathologic- Lead point
Causes of nonidiopathic adult intestinal intussusception*
Enteric (benign) Enteric (malignant) Colonic (benign) Colonic (malignant)

*Adopted from Clinics in Colon and Rectal Surgery 2017[7]

References

  1. Buettcher M, Baer G, Bonhoeffer J, Schaad UB, Heininger U (2007). "Three-year surveillance of intussusception in children in Switzerland". Pediatrics. 120 (3): 473–80. doi:10.1542/peds.2007-0035. PMID 17766518.
  2. Shimabukuro TT, Nguyen M, Martin D, DeStefano F (2015). "Safety monitoring in the Vaccine Adverse Event Reporting System (VAERS)". Vaccine. 33 (36): 4398–405. doi:10.1016/j.vaccine.2015.07.035. PMC 4632204. PMID 26209838.
  3. Bines JE, Liem NT, Justice FA, Son TN, Kirkwood CD, de Campo M, Barnett P, Bishop RF, Robins-Browne R, Carlin JB (2006). "Risk factors for intussusception in infants in Vietnam and Australia: adenovirus implicated, but not rotavirus". J. Pediatr. 149 (4): 452–60. doi:10.1016/j.jpeds.2006.04.010. PMID 17011313.
  4. Ebert EC (2008). "Gastrointestinal manifestations of Henoch-Schonlein Purpura". Dig. Dis. Sci. 53 (8): 2011–9. doi:10.1007/s10620-007-0147-0. PMID 18351468.
  5. Cohen DM, Conard FU, Treem WR, Hyams JS (1992). "Jejunojejunal intussusception in Crohn's disease". J. Pediatr. Gastroenterol. Nutr. 14 (1): 101–3. PMID 1573498.
  6. López-Tomassetti Fernández EM, Lorenzo Rocha N, Arteaga González I, Carrillo Pallarés A (2006). "Ileoileal intussusception as initial manifestation of Crohn's disease". Mcgill J Med. 9 (1): 34–7. PMC 2687895. PMID 19529808.
  7. "Thieme E-Journals - Clinics in Colon and Rectal Surgery / Abstract".

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