De Quervain's thyroiditis natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
De Quervain's thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease. Complications include [[hypothyroidism]] and rarely, [[tracheal compression|tracheal | De Quervain's thyroiditis develops after a [[viral]] [[prodrome]] and presents as [[painful]] [[thyroid gland]] with symptoms of [[thyrotoxicosis]]. It further leads to a [[euthyroid]] phase and eventually [[Hypothyroidism|hypothyroid]] phase before the complete resolution of the disease. Complications include [[hypothyroidism]] and rarely, [[esophageal]] or [[tracheal compression|tracheal compression]]. | ||
==Natural | ==Natural history, complications, and prognosis== | ||
== | === Natural history === | ||
De Quervain's thyroiditis develops after a [[viral]] [[prodrome]] and presents as [[painful]] [[thyroid gland]] with symptoms of [[thyrotoxicosis]]. It further leads to a [[euthyroid]] phase and eventually [[Hypothyroidism|hypothyroid]] phase before the complete resolution of the [[disease]].<ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref><ref name="pmid20886353">{{cite journal |vauthors=Engkakul P, Mahachoklertwattana P, Poomthavorn P |title=Eponym : de Quervain thyroiditis |journal=Eur. J. Pediatr. |volume=170 |issue=4 |pages=427–31 |year=2011 |pmid=20886353 |doi=10.1007/s00431-010-1306-4 |url=}}</ref><ref name="pmid2571803">{{cite journal |vauthors=Leibovitch G, Maaravi Y, Shalev O |title=Severe facial oedema and glossitis associated with mianserin |journal=Lancet |volume=2 |issue=8667 |pages=871–2 |year=1989 |pmid=2571803 |doi= |url=}}</ref> | |||
*[[ | ====1. Prodromal stage==== | ||
*[[ | It includes: | ||
*[[Low-grade fever]] and viral flu-like symptoms, such as [[sore throat]], [[myalgia]], [[arthralgia]], and [[malaise]]. | |||
*[[Fever|High-grade fever]] and [[neck pain]] with a tender and diffuse thyroid gland enlargement follow flu-like symptoms. | |||
====2. Hyperthyroid stage==== | |||
It follows the prodromal stage and includes the symptoms of [[thyrotoxicosis]] such as: | |||
*[[Tachycardia]] and [[Tremor|tremors]] | |||
*[[Irritability]] and [[nervousness]] | |||
====3. Euthyroid stage==== | |||
Thyrotoxic stage is followed by a 1–3-week period of [[Euthyroid|euthyroid phase]]. | |||
====4. Hypothyroid stage==== | |||
The transient hypothyroid stage lasts for 6-12 months. | |||
*Rarely, the [[hypothyroid]] stage may persist for a longer duration. | |||
===Complications=== | |||
Complications that can develop as a result of de Quervain's thyroiditis are:<ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref><ref name="pmid20886353">{{cite journal |vauthors=Engkakul P, Mahachoklertwattana P, Poomthavorn P |title=Eponym : de Quervain thyroiditis |journal=Eur. J. Pediatr. |volume=170 |issue=4 |pages=427–31 |year=2011 |pmid=20886353 |doi=10.1007/s00431-010-1306-4 |url=}}</ref><ref name="pmid2571803">{{cite journal |vauthors=Leibovitch G, Maaravi Y, Shalev O |title=Severe facial oedema and glossitis associated with mianserin |journal=Lancet |volume=2 |issue=8667 |pages=871–2 |year=1989 |pmid=2571803 |doi= |url=}}</ref> | |||
*[[Hypothyroidism]] | |||
*[[Tracheal compression]] | |||
*Esophageal compression | |||
===Prognosis=== | |||
Prognosis of de Quervain's thyroiditis is usually good. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Latest revision as of 18:20, 18 August 2017
De Quervain's thyroiditis Microchapters |
Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
De Quervain's thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease. Complications include hypothyroidism and rarely, esophageal or tracheal compression.
Natural history, complications, and prognosis
Natural history
De Quervain's thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease.[1][2][3]
1. Prodromal stage
It includes:
- Low-grade fever and viral flu-like symptoms, such as sore throat, myalgia, arthralgia, and malaise.
- High-grade fever and neck pain with a tender and diffuse thyroid gland enlargement follow flu-like symptoms.
2. Hyperthyroid stage
It follows the prodromal stage and includes the symptoms of thyrotoxicosis such as:
- Tachycardia and tremors
- Irritability and nervousness
3. Euthyroid stage
Thyrotoxic stage is followed by a 1–3-week period of euthyroid phase.
4. Hypothyroid stage
The transient hypothyroid stage lasts for 6-12 months.
- Rarely, the hypothyroid stage may persist for a longer duration.
Complications
Complications that can develop as a result of de Quervain's thyroiditis are:[1][2][3]
- Hypothyroidism
- Tracheal compression
- Esophageal compression
Prognosis
Prognosis of de Quervain's thyroiditis is usually good.
References
- ↑ 1.0 1.1 "Thyroiditis — NEJM".
- ↑ 2.0 2.1 Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
- ↑ 3.0 3.1 Leibovitch G, Maaravi Y, Shalev O (1989). "Severe facial oedema and glossitis associated with mianserin". Lancet. 2 (8667): 871–2. PMID 2571803.