Myxoma laboratory tests: Difference between revisions

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{{Myxoma}}
{{Myxoma}}
{{CMG}} {{AE}} {{AAM}}
{{CMG}} {{AE}} {{AAM}}{{MV}}
==Overview==
==Overview==
Complete blood count in patient with Myxoma may show [[anemia]] and elevated [[white blood cell]]s. The [[erythrocyte sedimentation rate]] may be increased.
 
[[Laboratory]] findings consistent with cardiac myxoma include [[anemia]], [[leukocytosis]], and elevated [[erythrocyte sedimentation rate]]. However, these results are generally non-diagnostic.
 
==Laboratory Findings==
==Laboratory Findings==
The [[clinical]] utility of laboratory tests in the [[diagnosis]] of cardiac myxoma remains nonspecific. [[Laboratory]] findings consistent with cardiac myxoma include [[anemia]], [[leukocytosis]] and elevated [[erythrocyte sedimentation rate]].<ref name="pmid7477198">{{cite journal |vauthors=Reynen K |title=Cardiac myxomas |journal=N. Engl. J. Med. |volume=333 |issue=24 |pages=1610–7 |year=1995 |pmid=7477198 |doi=10.1056/NEJM199512143332407 |url=}}</ref>
===Blood tests===
===Blood tests===
A complete blood count may show:
 
*[[Anemia]].
There is no specific blood test for the diagnosis of cardiac myxoma. However, constitutional [[Symptom|symptoms]] are associated with the following [[Cell (biology)|cell blood count]] ([[Complete blood count|CBC]]) findings:<ref name="pmid24599357">{{cite journal |vauthors=Hartig I, Kraatz EG, Beurich HW, Moosig F |title=[Atrial myxoma with clinical signs of systemic inflammatory disease.] |journal=Z Rheumatol |volume= |issue= |pages= |year=2014 |pmid=24599357 |doi=10.1007/s00393-013-1347-y |url=}}</ref>
*Elevated [[white blood cell]]s.
 
*Elevated [[ESR]].
*[[Anemia]] - [[Normochromic anemia|Normochromic]] or [[Hypochromic anemia|hypochromic]]
*[[Leukocytosis]]
*Elevated [[erythrocyte sedimentation rate]] (ESR)
*Elevated [[C-reactive protein]]
*Serum globulin level ([[hypergammaglobulinemia]]):
**A1-globulin [[serum]] levels can be found in [[patients]] with cardiac myxoma, and have been proposed as predictive markers of [[embolic]] accidents. <ref name="pmid10064362">{{cite journal |vauthors=Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I |title=Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience |journal=J Cardiovasc Surg (Torino) |volume=37 |issue=6 Suppl 1 |pages=113–7 |year=1996 |pmid=10064362 |doi= |url=}}</ref>
*Serum [[IL-6]]:
**Atrial myxoma cells are capable of producing [[Interleukin 6|Interleukin-6]] [[IL-6|(IL-6]]). Consequently, [[IL-6]] is used as a marker of recurrence in cardiac myxomas.<ref name="pmid26351445">{{cite journal |vauthors=Ezerioha N, Feng W |title=Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6 |journal=Case Rep Neurol |volume=7 |issue=2 |pages=152–5 |year=2015 |pmid=26351445 |pmc=4560324 |doi=10.1159/000437256 |url=}}</ref>
 
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Disease]]
[[Category:Disease]]
[[Category:Cardiology]]
[[Category:Cardiology]]
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Latest revision as of 14:56, 16 April 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]Maria Fernanda Villarreal, M.D. [3]

Overview

Laboratory findings consistent with cardiac myxoma include anemia, leukocytosis, and elevated erythrocyte sedimentation rate. However, these results are generally non-diagnostic.

Laboratory Findings

The clinical utility of laboratory tests in the diagnosis of cardiac myxoma remains nonspecific. Laboratory findings consistent with cardiac myxoma include anemia, leukocytosis and elevated erythrocyte sedimentation rate.[1]

Blood tests

There is no specific blood test for the diagnosis of cardiac myxoma. However, constitutional symptoms are associated with the following cell blood count (CBC) findings:[2]

References

  1. Reynen K (1995). "Cardiac myxomas". N. Engl. J. Med. 333 (24): 1610–7. doi:10.1056/NEJM199512143332407. PMID 7477198.
  2. Hartig I, Kraatz EG, Beurich HW, Moosig F (2014). "[Atrial myxoma with clinical signs of systemic inflammatory disease.]". Z Rheumatol. doi:10.1007/s00393-013-1347-y. PMID 24599357.
  3. Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I (1996). "Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience". J Cardiovasc Surg (Torino). 37 (6 Suppl 1): 113–7. PMID 10064362.
  4. Ezerioha N, Feng W (2015). "Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6". Case Rep Neurol. 7 (2): 152–5. doi:10.1159/000437256. PMC 4560324. PMID 26351445.


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