Myxoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]Ahmad Al Maradni, M.D. [3]


Cardiac myxoma is a rare disease with a reported prevalence of 0.03% in general population. The incidence of cardiac myxoma is about 1/ 100,000 per year. The majority of patients with cardiac myxoma are diagnosed between 30 to 60 years; children are rarely affected. Females are more commonly affected with cardiac myxoma than men. The female-to-male ratio is approximately 1.8 to 1. Cardiac myxomas represent 78% of heart tumors.

Epidemiology and Demographics


  • The prevalence of cardiac myxoma is reported as 0.03% in general population.[1][2]


  • The incidence of benign cardiac tumor including cardiac myxoma is about 1/100,000 per year.[1]


  • The mean age of patients at diagnosis is 50 years, most patients are between 30-60 age range.[3]
  • Cardiac myxomas are rare in children. However, in the pediatric population cardiac myxomas are more likely to be related with familial forms such as the (Carney complex).[4]


  • Females are more commonly affected with cardiac myxoma than men. The female-to-male ratio is approximately 1.8 to 1.[5]
  • Patients with Carney complex, tend to be younger and male.[5]


  1. 1.0 1.1 Walpot J, Shivalkar B, Rodrigus I, Pasteuning WH, Hokken R (2010). "Atrial myxomas grow faster than we think". Echocardiography. 27 (10): E128–31. doi:10.1111/j.1540-8175.2010.01186.x. PMID 20545988.
  2. Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR (2000). "Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation". Radiographics. 20 (4): 1073–103, quiz 1110–1, 1112. doi:10.1148/radiographics.20.4.g00jl081073. PMID 10903697.
  3. Siminelakis S, Kakourou A, Kakourou A, Batistatou A, Batistatou A, Sismanidis S, Sismanidis S, Ntoulia A, Tsakiridis K, Syminelaki T, Syminelaki T, Apostolakis E, Apostolakis E, Zarogoulidis P, Tsiouda T, Katsikogiannis N, Kougioumtzi I, Dryllis G, Machairiotis N, Mpakas A, Beleveslis T, Zarogoulidis K (March 2014). "Thirteen years follow-up of heart myxoma operated patients: what is the appropriate surgical technique?". J Thorac Dis. 6 Suppl 1: S32–8. doi:10.3978/j.issn.2072-1439.2013.10.21. PMC 3966159. PMID 24672697.
  4. Arciniegas E, Hakimi M, Farooki ZQ, Truccone NJ, Green EW (1980). "Primary cardiac tumors in children". J. Thorac. Cardiovasc. Surg. 79 (4): 582–91. PMID 7359937.
  5. 5.0 5.1 Yoon DH, Roberts W (2002). "Sex distribution in cardiac myxomas". Am. J. Cardiol. 90 (5): 563–5. PMID 12208428.

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