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For patient information page on this topic click [[Loefflers syndrome (patient information)|here]]
For patient information page on this topic click [[Loefflers syndrome (patient information)|here]]
{{Infobox disease
{{Loefflers syndrome}}
| Name            = Loeffler's syndrome
{{CMG}}; {{AE}} {{Soroush}}
| Image          =
| Caption        =
| DiseasesDB      = 7580
| ICD10          = {{ICD10|J|82||j|80}}
| ICD9            = {{ICD9|518.3}}
| ICDO            =
| OMIM            =
| MedlinePlus    = 000105
| MeshID          = D011657


}}
{{SK}} Loeffler's syndrome; Löffler disease; Löffler pneumonia; Löffler syndrome; Löffler's syndrome; Simple pulmonary eosinophilia; Tropical eosinophilic pneumonia
{{Loefflers syndrome}}
 
{{CMG}} {{AE}} {{RT}}
==[[Loefflers syndrome overview|Overview]]==


{{SK}} Löffler's syndrome; pulmonary infiltrates with eosinophilia; simple pulmonary eosinophilia; cryptogenic eosinophilic pneumonia;
==[[Loefflers syndrome historical perspective|Historical Perspective]]==


Löffler disease; Loffler pneumonia
==[[Loefflers syndrome pathophysiology|Pathophysiology]]==


== Overview ==
==[[Loefflers syndrome causes|Causes]]==


'''Loeffler's syndrome''' is a [[disease]] in which [[eosinophil]]s accumulate in the [[lung]] in response to a [[parasite|parasitic]] infection.
==[[Loefflers syndrome differential diagnosis|Differentiating Loefflers syndrome from other Diseases]]==


== Historical perspective ==
==[[Loefflers syndrome epidemiology and demographics|Epidemiology and Demographics]]==


It was first described in 1932 by [[Wilhelm Löffler (doctor)|Wilhelm Löffler]]<ref>{{cite journal |author=Löffler, W. |title=Zur Differential-Diagnose der Lungenifiltrierungen. I. Frühfiltrate unter besonerer Berücksichtigung der Rückbildungszeiten |journal=Beiträge zum Klinik der Tuberkulose |volume=79 |issue= |pages=338–367 |year=1932 }}<br/>{{cite journal |author=Löffler, W. |title=Zur Differential-Diagnose der Lungenifiltrierungen. II. Über flüchtige Succedan-Infiltrate (mit Eosinophilie) |journal=Beiträge zum Klinik der Tuberkulose |volume=79 |pages=368–382 |year=1932 }}<br/>{{cite journal |author=Löffler, W. |title=Flüchtige Lungeninfiltrate mit Eosinophilia |journal=Klinische Wochjenschrift |volume=14 |pages=297–9 |year=1935 |publisher=Berlin |doi=10.1007/BF01782394 |issue=9 }}</ref> in cases of [[eosinophilic pneumonia]] caused by the parasites ''[[Ascaris lumbricoides]]'',<ref>{{GPnotebook|463077386}}</ref> ''[[Strongyloides stercoralis]]'' and the [[hookworm]]s ''[[Ancylostoma duodenale]]'' and ''[[Necator americanus]]''.
==[[Loefflers syndrome risk factors|Risk Factors]]==


== Pathophysiology ==
==[[Loefflers syndrome natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


Infecting larvae reach the lungs via the bloodstream, penetrate into alveoli, and ascend the airways before descending the alimentary tract into the small bowel. Alveolar penetration triggers off an allergic reaction leading to pulmonary eosinophilia.
==Diagnosis==
[[Loefflers syndrome history and symptoms|History and Symptoms]] | [[ Loefflers syndrome physical examination|Physical Examination]] | [[Loefflers syndrome laboratory findings|Laboratory Findings]] | [[Loefflers syndrome electrocardiogram|Electrocardiogram]] | [[Loefflers syndrome chest x ray|Chest X Ray]] | [[Loefflers syndrome CT|CT]] | [[Loefflers syndrome echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Loefflers syndrome other imaging findings|Other Imaging Findings]] | [[Loefflers syndrome other diagnostic studies|Other Diagnostic Studies]]


== Causes ==
==Treatment==
[[Loefflers syndrome medical therapy|Medical Therapy]] | [[Loefflers syndrome primary prevention|Primary Prevention]] | [[Loefflers syndrome secondary prevention|Secondary Prevention]] | [[Loefflers syndrome cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Loefflers syndrome future or investigational therapies|Future or Investigational Therapies]]


* [[Ascaris lumbricoides]]
==Case Studies==
* [[Strongyloides stercoralis]]
[[Loefflers syndrome case study one|Case #1]]
* [[Ancylostoma duodenale]]
* [[Necator americanus]]


== References ==
==Related Pages==
{{reflist|2}}
*[[Eosinophilic pneumonia]]
*[[Parasitic pneumonia]]
*[[Pneumonia]]


[[Category:Immunology]]
[[Category:Infectious diseases]]
[[Category:Pulmonology]]
[[Category:Pulmonology]]
[[Category:Infectious diseases]]
[[Category:Immunology]]
[[Category:Grammar]]

Latest revision as of 15:40, 19 July 2019


For patient information page on this topic click here

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Laboratory Findings

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CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Synonyms and keywords: Loeffler's syndrome; Löffler disease; Löffler pneumonia; Löffler syndrome; Löffler's syndrome; Simple pulmonary eosinophilia; Tropical eosinophilic pneumonia

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Loefflers syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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